s-isomer — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3700	SCH900776 (S-isomer)	MK-8776 S-isomer,SCH900776 S-isomer	Chk , CDK
	SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM). It also inhibitors Chk2 (IC50: 1500 nM) and cyclin-dependent kinase CDK2 (IC50: 16...		Chk , CDK
T60196	IHMT-PI3Kδ-372 S-isomer		PI3K
	IHMT-PI3Kδ-372 S-isomer is a potent and selective PI3Kδ inhibitor with an IC50 of 14 nM. IHMT-PI3Kδ-372 S-isomer shows high selectivity over other class I PI3Ks (56∼83 fold) and other protein kinases. IHMT-PI3Kδ-372 can ...		PI3K
T19572	T4-ATA (S-isomer)		Others
	T4-ATA S-isomer, the active form of the thyroid hormone, represents the S-isomer of T4-ATA.		Others
T19571	T3-ATA (S-isomer)		Others
	T3-ATA S-isomer, the S-isomer of T3-ATA, represents the active form of the thyroid hormone.		Others
T30261	AZD6482 (S-isomer)	AZD-6482,AZD 6482,AZD6482 (S),AZD6482
	AZD6482 (S-isomer) is a potent, selective, ATP-competitive PI3Kβ inhibitor (IC(50) 0.01 μm), which can inhibit insulin-induced in vitro glucose uptake by human adipocytes (IC(50) is 4.4 μm).
T63166L	(S, R)-LSN 3318839	(S, R)-LSN 3318839(Isomer-2764704-18-7)	Glucagon Receptor
	(S, R)-LSN 3318839 is an allosteric modulator of the glucagon-like peptide-3318839 receptor (GLP-1R) that has demonstrated powerful hypoglycemic effects in animal models alone or in combination with sitagliptin.		Glucagon Receptor
T29007	Trichostatin A S-isomer	(-)-Trichostatin A
	Trichostatin A S-isomer is the s-isomer of Trichostatin A. Trichostatin A is a histone deacetylase inhibitors (HDIs or HDACIs) that have a broad spectrum of epigenetic activities. Trichostatin A inhibits HDACs 1, 3, 4, 6...
T27933	LY243246	LY249543 disodium,LY249543 sodium,LY 249543,LY-249543,S-isomer of lometrexol,DB04322,LY249543
	LY249543, the S-isomer of lometrexol, is an inhibitor of Methylenetetrahydrofolate Dehydrogenase/Cycl.
T10545	BIO-32546		PDE
	BIO-32546 (S-isomer) is a highly potent regulator of autotaxin (ATX) with an IC50 value of 1 nM.		PDE
T12644L	(S)-Thalidomide	(S)-(-)-Thalidomide	Apoptosis
	(S)-Thalidomide ((S)-(-)-Thalidomide) is the S-isomer of Thalidomide with immunomodulatory, anti-inflammatory, anticancer, anti-angiogenic and pro-apoptotic activities, and is used in the study of leprosy erythema nodosu...		Apoptosis
T22420	(S)-Viloxazine Hydrochloride	(S)-Viloxazine HCl	Norepinephrine
	(S)-Viloxazine Hydrochloride, the S-isomer of Viloxazine. Viloxazine is a selective norepinephrine reuptake inhibitor (NRI) that can be used as an antidepressant.		Norepinephrine
T4765	L-Norleucine	(S)-Norleucine,alpha-Aminocaproic acid,(S)-2-Aminohexanoic acid	Influenza Virus , Endogenous Metabolite
	L-Norleucine ((S)-Norleucine) is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.		Influenza Virus , Endogenous Metabolite
T50052	1,2-diphenylpropan-2-amine		Others
	1,2-Diphenylpropan-2-amine is the monohydrochloride metabolite of the (S,R)-isomer of Remacemide.1,2-Diphenylpropan-2-amine has anticonvulsant properties.		Others
T20626	Esomeprazole		Proton pump , Cysteine Protease
	Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Esomeprazole is a proton pump inhibitors (PPI).		Proton pump , Cysteine Protease
T0785	Dexchlorpheniramine Maleate	S-(+)-Chlorpheniramine maleate salt	Dopamine Receptor , 5-HT Receptor , Norepinephrine , Histamine Receptor
	Dexchlorpheniramine Maleate (S-(+)-Chlorpheniramine maleate salt) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It is the pharmacologically active d...
T0493	L-Tyrosine	Tyrosine,P-Tyrosine,L-p-Tyrosine,(S)-Tyrosine	Amino Acids and Derivatives , Endogenous Metabolite
	L-Tyrosine ((S)-Tyrosine) is a naturally occurring tyrosine and is synthesized in vivo from L-phenylalanine, considered a non-essential amino acid. L-Tyrosine(L-p-Tyrosine) is the levorotatory isomer of the aromatic amin...		Amino Acids and Derivatives , Endogenous Metabolite
T60224	1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-		GluR
	1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986. S 18986 is a AMPA receptor positive modulator with EC2 (Concentration that doubles the intensity of...		GluR
T2686L	Esomeprazole Sodium	(S)-Omeprazole sodium	ATPase , Proton pump
	Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Esomeprazole acts as an exosome inhibitor by blocking the exosome release via the i...		ATPase , Proton pump
T2686	Esomeprazole Magnesium	(S)-Omeprazole magnesium,NEXIUM,(-)-Omeprazole magnesium	ATPase , Proton pump
	Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.Esomeprazole magnesium acts as an exosome inhibitor by block...		ATPase , Proton pump
T13252	(S)-Rasagiline	TVP1022,S-PAI	Others
	(S)-Rasagiline is rasagiline S-isomer, and is an agent of anti-Parkinson.		Others