rab — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8473	MLS000532223		Rho , Ras
	MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).		Rho , Ras
T5642	Tegatrabetan	BC2059	Wnt/beta-catenin
	Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.		Wnt/beta-catenin
T34249	Rabeximod	ROB-803	TLR
	Rabeximod is a potent immunomodulator that reduces the severity of autoimmune diseases in rat models. Rabeximod inhibits arthritis in a time-dependent manner by stimulating TLR2 and TLR4 downstream to block the activatio...		TLR
T17155	Trabectedin	Ecteinascidin 743,ET-743	Apoptosis , Reactive Oxygen Species
	Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research. Trabectedin inhibits cell growth of MX-1, MCF7 and MCF7/DXR cells with IC50 values of 0...		Apoptosis , Reactive Oxygen Species
T5670	Isobutylparaben		Others , Antibacterial
	Isobutylparaben is a preservative and preservative insecticide.		Others , Antibacterial
T30677L	C15AlkOPP Tetrabutylamine salt(946615-44-7 Free base)	C15AlkOPP Tetrabutylamine salt(946615-44-7 Free base)	Others
	C15AlkOPP Tetrabutylamine salt is a “clickable” alkyne-modified analogs of the lipid substrates farnesyl diphosphate (FPP).		Others
TNU0187	2',5-Difluoro-2'-deoxy-1-arabinosyluracil	2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine	Nucleoside Antimetabolite/Analog
	2',5-Difluoro-2'-deoxy-1-arabinosyluracil (2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine) is a urinary pyrimidine nucleoside analogue with potential antiepileptic and antihypertensive activity, which can be used to study an...		Nucleoside Antimetabolite/Analog
T5268	D-Arabitol	D-Lyxitol	Others , Endogenous Metabolite
	D-Arabitol (D-Lyxitol) is a polyol. Polyols are sugar alcohols linked to the pentose phosphate pathway (PPP). Polyols occur in body fluids. It is thought that D-arabitol is a metabolic end-product in humans.		Others , Endogenous Metabolite
T2S0461	D-Arabinose		Others , Endogenous Metabolite
	Inexpensive starting material for chiral synthesis.		Others , Endogenous Metabolite
T3153	Serabelisib	TAK-117,INK1117,MLN1117	PI3K , mTOR
	Serabelisib (INK1117) is a p110α/β/γ/δ inhibitor (IC50: 15/4.5/1.9/13.39 μM).		PI3K , mTOR
T6603	Nelarabine	GW 506U78,Nelzarabine,506U78	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.
T34914	Trabodenoson	INNO-8875,INO-8875,PJ875,PJ-875,INNO 8875,INNO8875,PJ 875	Adenosine Receptor
	Trabodenoson (INO-8875) is a selective and potent adenosine A1 receptor agonist, an adenosine analog, for the study of primary open-angle glaucoma.		Adenosine Receptor
T6501	Fludarabine Phosphate	NSC 312887 Phosphate,fludara Phosphate,F-ara-A (NSC 312887) Phosphate,F-ara-AMP	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Fludarabine Phosphate (NSC 312887 Phosphate) is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Fludarabine phosphate is rapidl...
T0588	D-(-)-Arabinose	D(-)-Arabinose,D-arabinose	Others
	D-(-)-Arabinose is a reducing sugar useful as a substrate in analysis of arabinose isomerases and synthesis of D-erythroascorbic acid in yeast. It shows strong growth inhibition against the Caenorhabditis elegans with an...		Others
T0927	Butylparaben	Butyl 4-hydroxybenzoate,Butyl parahydroxybenzoate	Endogenous Metabolite , Antibacterial , Antibiotic
	Butylparaben (Butyl 4-hydroxybenzoate) is a standardized chemical allergen, increasing histamine release, and cell-mediated immunity.		Endogenous Metabolite , Antibacterial , Antibiotic
TNU0014	1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil		Apoptosis
	1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is a Nucleoside, fluoro-modified nucleoside; Arabino-nucleosidde.		Apoptosis
T16747	Riboflavin Tetrabutyrate		Reactive Oxygen Species
	Riboflavin Tetrabutyrate is a lipophilic flavin derivative. Riboflavin Tetrabutyrate has antioxidative and lipid peroxide-removing activity.		Reactive Oxygen Species
T0297	Clofarabine	Clofarex,Evoltra,Clolar	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Autophagy
	Clofarabine (Clofarex)m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.
TQ0236	Tirabrutinib	ONO-4059,GS-4059,Velexbru	BTK
	Tirabrutinib (GS-4059) (ONO-4059) is an orally active Bruton’s Tyrosine Kinase (Btk) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib irreversibly and covalently binds to Btk and ...		BTK
T12311	Tirabrutinib hydrochloride	ONO-4059 (hydrochloride),GS-4059 (hydrochloride)	BTK
	Tirabrutinib hydrochloride (GS-4059 (hydrochloride)) is a selective and novelBTK with IC50 2.2 nm inhibitor.		BTK