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Riboflavin Tetrabutyrate

Riboflavin Tetrabutyrate
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Purity:98.34%
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Riboflavin Tetrabutyrate

Catalog No. T16747Cas No. 752-56-7
Riboflavin Tetrabutyrate is a lipophilic flavin derivative. Riboflavin Tetrabutyrate has antioxidative and lipid peroxide-removing activity.
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Pack SizePriceAvailabilityQuantity
50 mg$33In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Product Introduction

Bioactivity
Description
Riboflavin Tetrabutyrate is a lipophilic flavin derivative. Riboflavin Tetrabutyrate has antioxidative and lipid peroxide-removing activity.
In vitro
Riboflavin Tetrabutyrate effectively suppresses NADPH-coupled and ascorbate-induced microsomal lipid peroxidation, also inhibiting oxygen uptake during such peroxidation. It appears to exert its antioxidative effects during or after the enzymic oxidation-reduction process, specifically after the abstraction of a hydrogen atom as a free radical from the active methylene group in polyunsaturated fatty acids[1].
In vivo
Riboflavin Tetrabutyrate might improve the metabolism of lipids in patients suffering from atherosclerosis, diabetes, fatty liver, and so on through the inhibition of lipid peroxide, thereby resulting in a decrease of the elevated serum lipid. The increase in hepatic 3-ketoacyl-CoA thiolase activity indicates that prolonged Riboflavin Tetrabutyrate administration induces an increased beta-oxidation of fatty acid in the liver. Feeding of Riboflavin Tetrabutyrate causes an increase in the hepatic activity of 3-ketoacyl-CoA thiolase by 50% of the control level, while the activities of renal 3-ketoacyl-CoA thiolase and of hepatic and renal acyl-CoA synthetase and acyl-CoA dehydrogenase remain unaffected [1][2].
Chemical Properties
Molecular Weight656.72
FormulaC33H44N4O10
Cas No.752-56-7
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 100 mg/mL (152.27 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5227 mL7.6136 mL15.2272 mL76.1359 mL
5 mM0.3045 mL1.5227 mL3.0454 mL15.2272 mL
10 mM0.1523 mL0.7614 mL1.5227 mL7.6136 mL
20 mM0.0761 mL0.3807 mL0.7614 mL3.8068 mL
50 mM0.0305 mL0.1523 mL0.3045 mL1.5227 mL
100 mM0.0152 mL0.0761 mL0.1523 mL0.7614 mL

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