Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Riboflavin Tetrabutyrate is a lipophilic flavin derivative. Riboflavin Tetrabutyrate has antioxidative and lipid peroxide-removing activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 33.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Riboflavin Tetrabutyrate is a lipophilic flavin derivative. Riboflavin Tetrabutyrate has antioxidative and lipid peroxide-removing activity. |
In vitro | Riboflavin Tetrabutyrate effectively suppresses NADPH-coupled and ascorbate-induced microsomal lipid peroxidation, also inhibiting oxygen uptake during such peroxidation. It appears to exert its antioxidative effects during or after the enzymic oxidation-reduction process, specifically after the abstraction of a hydrogen atom as a free radical from the active methylene group in polyunsaturated fatty acids[1]. |
In vivo | Riboflavin Tetrabutyrate might improve the metabolism of lipids in patients suffering from atherosclerosis, diabetes, fatty liver, and so on through the inhibition of lipid peroxide, thereby resulting in a decrease of the elevated serum lipid. The increase in hepatic 3-ketoacyl-CoA thiolase activity indicates that prolonged Riboflavin Tetrabutyrate administration induces an increased beta-oxidation of fatty acid in the liver. Feeding of Riboflavin Tetrabutyrate causes an increase in the hepatic activity of 3-ketoacyl-CoA thiolase by 50% of the control level, while the activities of renal 3-ketoacyl-CoA thiolase and of hepatic and renal acyl-CoA synthetase and acyl-CoA dehydrogenase remain unaffected [1][2]. |
Molecular Weight | 656.72 |
Formula | C33H44N4O10 |
CAS No. | 752-56-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (152.27 mM)
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Riboflavin Tetrabutyrate 752-56-7 Immunology/Inflammation Metabolism NF-Κb Reactive Oxygen Species inhibit Inhibitor Riboflavin inhibitor