pex — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T81527	Pegloxenatide	PEX 168
	Pegloxenatide, a glucagon-like peptide-1 receptor (GLP-1 RA) agonist, is utilized in type 2 diabetes research [1].
T8310	MMP-9-IN-1		MMP
	MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9).		MMP
TP1930L1	Spexin acetate(1370290-58-6 free base)		Neuropeptide Y Receptor
	Spexin acetate is a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galanin receptor 1. Endogenous satiety-inducing peptide; inhibits...		Neuropeptide Y Receptor
T16475	Pexacerfont	BMS-562086	CRFR
	Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor).		CRFR
T21787L	Azepexole hydrochloride	4H-Oxazolo[4,5-d]azepin-2-amine, 6-ethyl-5,6,7,8-tetrahydro-, hydrochloride (1:1)	Adrenergic Receptor
	Azepexole hydrochloride (4H-Oxazolo[4,5-d]azepin-2-amine, 6-ethyl-5,6,7,8-tetrahydro-, hydrochloride (1:1)) is a potent α2-Adrenoceptor agonist with anaesthetic effects.		Adrenergic Receptor
T6934	Pexmetinib	ARRY-614	Tie-2 , p38 MAPK , Autophagy
	Pexmetinib (ARRY-614) (ARRY-614) is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line. Phase 1.		Tie-2 , p38 MAPK , Autophagy
T1476	Pramipexole	SND 919	Dopamine Receptor
	Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of transient serum enzyme elevations during treatment but has not...		Dopamine Receptor
T11011	Dexpramipexole dihydrochloride	KNS-760704 dihydrochloride,R-(+)-Pramipexole dihydrochloride,(R)-Pramipexole dihydrochloride	Dopamine Receptor
	Dexpramipexole dihydrochloride (KNS-760704 dihydrochloride) ((R)-Pramipexole dihydrochloride) is a neuroprotective agent and is a weak non-ergoline dopamine agonist.		Dopamine Receptor
T14490	Talipexole dihydrochloride	Domnin,B-HT 920 dihydrochloride	Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
	Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal membrane fractions with Ki values of 0.35 μM and 0.22 μM, ...		Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
T0322	Fipexide		Dopamine Receptor , AChR
	Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983. It was served as a nootropic drug in France and Italy, mainly for the therapy of senile dementia, but is...		Dopamine Receptor , AChR
T2115	Pexidartinib	PLX-3397	Apoptosis , c-Fms , FLT , CSF-1R , c-Kit
	Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity.		Apoptosis , c-Fms , FLT , CSF-1R , c-Kit
T6951	Pramipexole dihydrochloride hydrate	Pramipexole 2HCl Monohydrate,Mirapex	Dopamine Receptor
	Pramipexole dihydrochloride hydrate (Mirapex) is the hydrochloride salt of pramipexole, a benzothiazole derivative. As a nonergot dopamine agonist, pramipexole binds to D2 and D3 dopamine receptors in the striatum and su...		Dopamine Receptor
T11318	Dopexamine hydrochloride	FPL60278AR	Adrenergic Receptor
	Dopexamine hydrochloride (FPL60278AR) is a β2-adrenergic receptor agonist. Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regi...		Adrenergic Receptor
T8653	DOPEXAMINE		Dopamine Receptor
	Dopexamine is a dopaminergic agonist		Dopamine Receptor
T81503	PEX5-PEX14 PPI-IN-2
	Compound 12, also known as PEX5-PEX14 PPI-IN-2, is a PEX14-PEX5 protein-protein interaction (PPI) inhibitor with half-maximal effective concentration (EC50) values of 5 µM in T. b. brucei and 17 µM in HepG2 cells. It is ...
T76002	Spexin TFA
	Spexin TFA, a potent agonist for galanin receptor 2/3 (GAL2/GAL3) with EC50 values of 45.7 and 112.2 nM respectively, shows no significant activity towards galanin receptor 1. As an endogenous peptide promoting satiety, ...
T83717	Cys-Pexiganan TFA
	Cys-pexiganan, a derivative of pexiganan with an added N-terminal cysteine, is an antimicrobial peptide effective against P. aeruginosa and S. aureus, with minimum inhibitory concentrations (MICs) of 64 and 16 µg/ml, res...
T20845	Kopexil	Mexoryl SAG,Aminexil
	Kopexil, an N-oxide, is used to treat hair loss.
T22332	Fipexide hydrochloride		Others
	Fipexide (hydrochloride) is a kind of psychoactive drug of the piperazine class.		Others
T6934L	Pexmetinib hydrochloride
	Pexmetinib hydrochloride is a biochemical.