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Search Results for " nst "

Targets

27

Compounds

3

Natural Products

15

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T15549 Icosabutate NST-4016,PRC-4016 Others
Icosabutate (NST-4016) is an orally active derivative of eicosapentaenoic acid that inhibits hepatic inflammation and fibrosis in NASH, improves cardiovascular risk profiles in statin-treated patients with residual hyper...
T27643 Izonsteride LY-320236,LY320236,UNII-A5E8C36F34 Reductase
Izonsteride (LY320236) is a selective and potent 5alpha reductase inhibitor with dual action on the type I and type II isoforms of the enzyme.Izonsteride is used in the treatment of oncology and genitourinary disorders, ...
T8883 Pizuglanstat Others , Prostaglandin Receptor
Pizuglanstat is a hematopoietic prostaglandin synthase inhibitor.
T71812 Protonstatin-1
Protonstatin-1 is used as a hypoglycemic agent and as a compound for the treatment of Alzheimer's disease, inhibits IGFIR kinase activity and can be used in cancer research.
T38889 Thailanstatin A
Thailanstatin A is an ultra-potent inhibitor of eukaryotic RNA splicing (IC50 =650 nM). Thailanstatin A inhibits multiple cancer cell lines via non-covalent binding to the SF3b subunit of the U2 snRNA subcomplex of the s...
T26955 Cavosonstat N91115,N 91115,N-91115 GSNOR , CFTR
Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor that promotes cystic fibrosis transmembrane conductance regulator (CFTR) maturation and plasma membrane stabilization.Cavosonstat ...
T15271 Denifanstat FASN-IN-2,TVB2640,TVB-2640 Fatty Acid Synthase
Denifanstat (FASN-IN-2) is a Fatty Acid Synthase (FASN) inhibitor(IC50 of 0.052 μM and an EC50 of 0.072 μM),with potential antineoplastic activity.
T32310 Johnstonol
Johnstonol is an specifically halogenated epoxide obtained from the red alga.
T34916 Transtinib
Transtinib is an effective and irreversible EGFR tyrosine kinase inhibitor (EGFR-TKI) that is active against L858R/T790M mutated NSCLC cell lines and xenografts.
T25127 Azalanstat RS-21607,RS 21607,RS21607
Azalanstat is a lanosterol 14 alpha-demethylase inhibitor. The enzyme catalyzes the first step in the conversion of lanosterol to cholesterol in mammals.
T61444 Nonsteroidal aromatase inhibitor 1
Nonsteroidal aromatase inhibitor 1 (Compound 13h) effectively inhibits the enzyme CYP19A1 with an IC50 value of 0.09 nM. Due to its potent inhibitory activity, Nonsteroidal aromatase inhibitor 1 holds promise for researc...
T34759 Synstab A Synstab-A
Synstab A is a microtubule stabilizer.
T79846 Friluglanstat PGE Synthase
Friluglanstat is an inhibitor of the enzyme prostaglandin E synthase (mPGES-1) and exhibits anti-inflammatory activity [1].
T79085 MC-VC-PAB-Cyclohexanediamine-Thailanstatin A DNA/RNA Synthesis
MC-VC-PAB-Cyclohexanediamine-Thailanstatin A is a spliceostatin analog and a drug-linker conjugate for antibody-drug conjugates (ADC), comprising the cytotoxic component Thailanstatin A and the cleavable linker (MC-vc-PA...
T62174 Protein deglycase DJ-1 against-1
Protein deglycase DJ-1 against-1 is a DJ-1-binding compound that crosses the blood-brain barrier and targets DJ1 in a dependent manner. protein deglycase DJ-1 against-1 is a neuroprotective agent with potential for Parki...
T70660 Azalanstat HCl
Azalanstat HCl is an anti-obesity drug acting as a lanosterol 14α-demethylase inhibitor. Azalanstat HCl has been shown to inhibit cholesterol synthesis in HepG2 cells, human fibroblasts, hamster hepatocytes and hamster l...
T70661 Azalanstat mesylate
Azalanstat mesylate is an anti-obesity drug acting as a lanosterol 14α-demethylase inhibitor. Azalanstat mesylate has been shown to inhibit cholesterol synthesis in HepG2 cells, human fibroblasts, hamster hepatocytes and...
T61423 Transthyretin-IN-1
Transthyretin-IN-1 (Compound 1d) is a potent inhibitor of transthyretin (TTR) fibril formation, making it a valuable tool for investigating Alzheimer’s disease [1].
T124035 Cajaninstilbene acid
Cajaninstilbene acid is a useful organic compound for research related to life sciences. The catalog number is T124035 and the CAS number is 87402-84-4.
T82465 Enlonstobart
Enlonstobart is a humanized IgG4-κ monoclonal antibody targeting PDCD1, functioning as both an immunostimulant and antineoplastic agent [1].
T78064 Synstatin (92-119) SSTN92-119 Integrin
Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 and attenuation of angiogenic growth factor activation, specific...
T39000 Zaloglanstat GRC-27864,ISC-27864
Zaloglanstat (ISC-27864) is a potent inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1). It is utilized in the research of various conditions, including asthma, osteoarthritis, rheumatoid arthritis, acute or ch...
T31763 Fenaminstrobin SYP 1620,SYP-1620,SYP1620
Fenaminstrobin is a biochemical.
T69233 Ganstigmine
Ganstigmine is an acetylcholinesterase inhibitor for Alzheimer's disease.
T69792 Atuzaginstat
Atuzaginstat is a bacterial protease lysine gingipain inhibitor.
T70874 Vipoglanstat
Vipoglanstat is a prostaglandin E synthase inhibitor and an anti-inflammatory. Vipoglanstat ameliorates leukocyte infiltration and lung injury resulting from both endotoxin-induced and sepsis-induced lung injury.
T37585 Ensartinib
Ensartinib (X-396) is a potent and dual ALK/MET inhibitor with IC50s of <0.4 nM and 0.74 nM, respectively. The ability of Ensartinib (X-396) to inhibit the growth of different cancer cell lines harboring ALK fusions or ...
Cat No. Product Name Synonyms Targets
T8626 Transtorine 1,4-DIHYDRO-4-OXOQUINOLINE-2-CARBOXYLIC ACID GluR , NMDAR
Transtorine (1,4-DIHYDRO-4-OXOQUINOLINE-2-CARBOXYLIC ACID) is a GluR and NMDA inhibitor.
T39071 Thailanstatin D
Thailanstatin D, an analogue of Thailanstatin A, inhibits AR-V7 gene splicing by disrupting the interaction between U2AF65 and SAP155, hindering their binding to the polypyrimidine tract situated between the branch point...
T38890 Thailanstatin C
Thailanstatin C, an antiproliferative agent derived from Burkholderia thailandensis MSMB43, functions as a potent inhibitor of pre-mRNA splicing (IC50 = 6.84 μM).

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-01296 SULT4A1 Protein, Human, Recombinant Human E. coli
Sulfotransferase 4A1 (ST4A1) is a member of the Sulfotransferase 1 family. ST4A1 is highly expressed in the cerebral cortex and frontal lobe, but no expression is detected in the pancreas. ST4A1 is a brain-specific sulfo...
TMPY-01756 Transthyretin Protein, Human, Recombinant (His) Human HEK293 Cells
Transthyretin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is E9KL36.
TMPK-01090 Transthyretin/Prealbumin Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Transthyretin is a highly conserved homotetrameric protein, mainly synthetized by the liver and the choroid plexus of brain. The carrier role of TTR is well-known; however, many other functions have emerged, namely in th...
TMPY-04919 Transthyretin Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Transthyretin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.6 kDa and the accession number is P07309.
TMPH-02454 Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (E. coli, His) MeV E. coli
Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 49.9 kDa and the accession num...
TMPY-05071 IgE Fc Protein, Human, Recombinant (Constant Domain 3 & 4, His) Human HEK293 Cells
IgE Fc Protein, Human, Recombinant (Constant Domain 3 & 4, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is AAB59395.1.
TMPH-02947 Transthyretin Protein, Mouse, Recombinant Mouse E. coli
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Transthyretin Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13....
TMPH-02453 Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (His) MeV Baculovirus Insect Cells
Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 46.9 kDa and the accession number is B8P...
TMPH-02946 Transthyretin Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Transthyretin Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. Th...
TMPY-00279 Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His) DENV E. coli
Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35.5 kDa and the ac...
TMPY-03352 Influenza A H7N2 (A/ruddy turnstone/New Jersey/563/2006) Hemagglutinin/HA Protein (His) H7N2 Baculovirus Insect Cells
Influenza A H7N2 (A/ruddy turnstone/New Jersey/563/2006) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is C6KLK6...
TMPJ-00824 Ig lambda constant 2 Protein, Human, Recombinant (His) Human HEK293 Cells
Immunoglobulin lambda constant region is constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recogniti...
TMPH-02115 KNSTRN Protein, Human, Recombinant (His) Human E. coli
N/A. KNSTRN Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 39.5 kDa and the accession number is Q9Y448?.
TMPY-00422 Influenza A H7N2 (A/ruddy turnstone/New Jersey/563/2006) Hemagglutinin/HA1 Protein (His) H7N2 HEK293 Cells
Influenza A H7N2 (A/ruddy turnstone/New Jersey/563/2006) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is C6KLK6.
TMPH-02242 Transthyretin Protein, Human, Recombinant (hFc & Myc) Human HEK293 Cells
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
SULT4A1 Protein, Human, Recombinant
TMPJ-01296
Species: Human
Expression System: E. coli
Transthyretin Protein, Human, Recombinant (His)
TMPY-01756
Species: Human
Expression System: HEK293 Cells
Transthyretin/Prealbumin Protein, Cynomolgus, Recombinant (His)
TMPK-01090
Species: Cynomolgus
Expression System: HEK293 Cells
Transthyretin Protein, Mouse, Recombinant (His)
TMPY-04919
Species: Mouse
Expression System: HEK293 Cells
Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (E. coli, His)
TMPH-02454
Species: MeV
Expression System: E. coli
IgE Fc Protein, Human, Recombinant (Constant Domain 3 & 4, His)
TMPY-05071
Species: Human
Expression System: HEK293 Cells
Transthyretin Protein, Mouse, Recombinant
TMPH-02947
Species: Mouse
Expression System: E. coli
Measles virus (MeV) (strain Edmonston-Schwarz vaccine) Nucleoprotein/NP Protein (His)
TMPH-02453
Species: MeV
Expression System: Baculovirus Insect Cells
Transthyretin Protein, Mouse, Recombinant (His & SUMO)
TMPH-02946
Species: Mouse
Expression System: E. coli
Dengue virus DENV-2 (strain New Guinea C) NS5 (methyltransferase domain)/Nonstructural protein 5 Protein (His)
TMPY-00279
Species: DENV
Expression System: E. coli
Influenza A H7N2 (A/ruddy turnstone/New Jersey/563/2006) Hemagglutinin/HA Protein (His)
TMPY-03352
Species: H7N2
Expression System: Baculovirus Insect Cells
Ig lambda constant 2 Protein, Human, Recombinant (His)
TMPJ-00824
Species: Human
Expression System: HEK293 Cells
KNSTRN Protein, Human, Recombinant (His)
TMPH-02115
Species: Human
Expression System: E. coli
Influenza A H7N2 (A/ruddy turnstone/New Jersey/563/2006) Hemagglutinin/HA1 Protein (His)
TMPY-00422
Species: H7N2
Expression System: HEK293 Cells
Transthyretin Protein, Human, Recombinant (hFc & Myc)
TMPH-02242
Species: Human
Expression System: HEK293 Cells
Cat No. Product Name
L4710 Nonsteroidal Anti-Inflammatory Compound Library

530 compounds
530 non-steroidal anti-inflammatory compounds for high-throughput and high-content screening.
TargetMol