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Search Result

Search Results for " nne "

Targets

Annexin A Chloride channel Calcium Channel Sodium Channel Potassium Channel Piezo Channel TRP/TRPV Channel HCN Channel Calcium Channel CDK

30

Compounds

2

Natural Products

15

Recombinant Proteins

4

Libraries

Cat No. Product Name Synonyms Targets
T10659 Ca2+ channel agonist 1 Calcium Channel , CDK
Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor nerve terminal dysfunction.
T77711 Calcium Channel antagonist 4 Calcium Channel
Calcium Channel antagonist 4 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).
T77712 Calcium Channel antagonist 3 Calcium Channel
Calcium Channel antagonist 3 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).
T10101 Calcium channel-modulator-1 Others , Calcium Channel
Calcium channel-modulator-1 is a calcium channel-modulator (IC50:0.8 μM) with specialisation to block aortic constriction.
T77710 Calcium Channel antagonist 2 WAY-327363 Calcium Channel
Calcium Channel antagonist 2 is a calcium channel antagonist (IC50=5-20 μM) that can be used to study diseases due to Ca2+ channels like pain and diabetes.
T72170 NaV1.2/1.6 channel blocker-1 Sodium Channel
NaV1.2/1.6 channel blocker-1 is a potent NaV1.2/1.6 channel blocker with inhibitory effects on rNaV1.6 and hNaV1.2.NaV1.2 channel blocker-1 can be used in the study of generalised epilepsy and movement disorders.
T10674 Potassium Channel Activator 1 ZINC34634569 Potassium Channel
Potassium Channel Activator 1 can be used in studies about the treatment of disorders or conditions wherein the dopaminergic system is disrupted such as mood disorders ADHD, schizophrenia, and other psychotic states.
T64203 T-Type calcium channel inhibitor 2
T-Type calcium channel inhibitor 2 (compound 6g) is a potent inhibitor of the T-type calcium channel, acting on Cav3.1 (α1G) (IC50: 31.0 μM), Cav3.2 (α1H) (IC50: 83.1 μM), Cav3.3 (α1I) (α1H) ( T-Type calcium channel inhi...
T60986 KCa2 channel modulator 2
KCa2 channel modulator 2 (compound 2q) is an effective subtype-selective K/Ca 2 channel positive modulator which shows similar potency on the human K Ca 2.3 channel and rat K Ca 2.2a subtypes, with EC50 values of 0.60 μM...
T72194 KCa1.1 channel activator-1
KCa1.1 Channel Activator-1, a hybrid derivative of Quercetin, selectively stimulates the vascular KCa1.1 channels while also blocking CaV1.2 channels. Additionally, it demonstrates weak myorelaxant activity.
T80275 Lynronne-2
Lynronne-2, an antimicrobial peptide, exhibits activity against Gram-positive bacteria, including methicillin-resistant MRSA strains (MIC: 32-256 μg/mL), and demonstrates effectiveness in combating P. aeruginosa infectio...
T79280 Nav1.3 channel inhibitor 1 Sodium Channel
Nav1.3 Channel Inhibitor 1 (Compound 15b) is a state-dependent inhibitor of the voltage-gated sodium channel Na v 1.3, with an IC50 value of 20 nM. It has the ability to cross the blood-brain barrier, making it applicabl...
T12948 Sodium Channel inhibitor 1 Others
Sodium Channel inhibitor1 is a novel and selective voltage-gated sodium channel for pain treatment. (IC50 Value of 0.16 uM and 0.41 uM for Na v1.7, V hold-90mV and Na v1.7, V hold-90mV)
T61605 SK3 Channel-IN-1
SK3 Channel-IN-1 (compound 7a) is a powerful and selective modulator of the SK3 channel. It demonstrates significant efficacy in inhibiting breast cancer MDA-MB-435 cell migration while maintaining low cytotoxicity in ot...
T12951 Sodium Channel inhibitor 2 Sodium Channel
Sodium Channel inhibitor 2 is a blocker of sodium channel.
T72195 KCa1.1 channel activator-2
KCa1.1 channel activator-2, a hybrid derivative of Quercetin, selectively stimulates the vascular KCa1.1 channels. This compound demonstrates significant myorelaxant activity.
T39816 Ceftaroline fosamil inner salt TAK-599 free acid,PPI0903freeacid
Ceftaroline fosamil (TAK-599) inner salt, a cephalosporin derivative, is an N-phosphono prodrug of anti-methicillin-resistant Staphylococcus aureus (MRSA) T-91825. Ceftaroline fosamil inner salt can be used for the resea...
T80274 Lynronne-1
Lynronne-1, an antimicrobial peptide, exhibits activity against Gram-positive bacteria, including multi-drug resistant (MDR) strains, with a minimal inhibitory concentration (MIC) of 8-32 μg/mL for methicillin-resistant ...
T81134 Sodium Channel inhibitor 4 Sodium Channel
Sodium Channel Inhibitor 4 is a compound that functions as a sodium channel inhibitor [1].
T12042 Minnelide Others
Minnelide is a prodrug of triptolide,and shows potent antitumor activity in a number of tumor types.
T65053 (Methoxycarbonylsulfamoyl)triethylammonium hydroxide, inner salt
(Methoxycarbonylsulfamoyl)triethylammonium hydroxide, inner salt is a useful organic compound for research related to life sciences. The catalog number is T65053 and the CAS number is 29684-56-8.
T71113 Minnelide free acid
Minnelide is an effective therapy against pancreatic cancer. Minnelide Inhibits Androgen Dependent, Castration Resistant Prostate Cancer Growth by Decreasing Expression of Androgen Receptor Full Length and Splice Variant...
T82403 Fibronectin Type III Connecting Segment Fragment 1-25
Fibronectin Type III Connecting Segment Fragment 1-25 is a peptide implicated in melanoma cell adhesion and critical for the development of the chicken peripheral nervous system [1] [2].
T82683 Connexin mimetic peptide 40GAP27
Connexin mimetic peptide 40GAP27, corresponding to the GAP27 domain of the second extracellular loop of the dominant vascular connexin (Cx40), designated as 40Gap27, is a biologically active peptide utilized to study the...
T82684 Connexin mimetic peptide 40,37GAP26
Connexin mimetic peptide 40,37GAP26, a biologically active peptide, matches the GAP26 domain of the extracellular loop of major vascular connexins Cx37 and Cx40, referred to as 37,40Gap26 based on Cx homology. It has bee...
T80276 Lynronne-3
Lynronne-3, an antimicrobial peptide, demonstrates activity against Gram-positive bacteria, including multi-drug resistant (MDR) strains, with a minimum inhibitory concentration (MIC) ranging from 32-128 μg/mL for methic...
TP1491 Kv3, Channel Containing Protein 567-585
Kv3 channel protein is expressed by parvalbumin (PV)-containing pallidal neurons.Kv3, Channel Containing Protein (567-585) corresponds to amino acids 567 to 585 fragment of the Kv3.1b channel containing protein.
T12153 N-type calcium channel blocker-1 Calcium Channel
N-type calcium channel blocker-1 is an orally active analgesic agent,shows high affinity to functionally block N-type calcium channels.
T60985 KCa2 channel modulator 1
KCa2 channel modulator 1 (compound 2o) is an effective subtype-selective K/Ca2 channel positive modulator that potentiates rat K Ca 2.2 channel subtype with an EC 50 value of 0.99 μM and human K Ca 2.3 channels subtype w...
T11927 M2 ion channel blocker Others
M2 ion channel blocker ,Antiviral agent, is capable of inhibiting and blocking the activity of M2 ion channel.

Compounds

Ca2+ channel agonist 1
T10659
Synonym:
Target: Calcium Channel, CDK
Calcium Channel antagonist 4
T77711
Synonym:
Target: Calcium Channel
Calcium Channel antagonist 3
T77712
Synonym:
Target: Calcium Channel
Calcium channel-modulator-1
T10101
Synonym:
Target: Others, Calcium Channel
Calcium Channel antagonist 2
T77710
Synonym: WAY-327363
Target: Calcium Channel
NaV1.2/1.6 channel blocker-1
T72170
Synonym:
Target: Sodium Channel
Potassium Channel Activator 1
T10674
Synonym: ZINC34634569
Target: Potassium Channel
T-Type calcium channel inhibitor 2
T64203
Synonym:
Target:
KCa2 channel modulator 2
T60986
Synonym:
Target:
KCa1.1 channel activator-1
T72194
Synonym:
Target:
Lynronne-2
T80275
Synonym:
Target:
Nav1.3 channel inhibitor 1
T79280
Synonym:
Target: Sodium Channel
Sodium Channel inhibitor 1
T12948
Synonym:
Target: Others
SK3 Channel-IN-1
T61605
Synonym:
Target:
Sodium Channel inhibitor 2
T12951
Synonym:
Target: Sodium Channel
KCa1.1 channel activator-2
T72195
Synonym:
Target:
Ceftaroline fosamil inner salt
T39816
Synonym: TAK-599 free acid,PPI0903freeacid
Target:
Lynronne-1
T80274
Synonym:
Target:
Sodium Channel inhibitor 4
T81134
Synonym:
Target: Sodium Channel
Minnelide
T12042
Synonym:
Target: Others
(Methoxycarbonylsulfamoyl)triethylammonium hydroxide, inner salt
T65053
Synonym:
Target:
Minnelide free acid
T71113
Synonym:
Target:
Fibronectin Type III Connecting Segment Fragment 1-25
T82403
Synonym:
Target:
Connexin mimetic peptide 40GAP27
T82683
Synonym:
Target:
Connexin mimetic peptide 40,37GAP26
T82684
Synonym:
Target:
Lynronne-3
T80276
Synonym:
Target:
Kv3, Channel Containing Protein 567-585
TP1491
Synonym:
Target:
N-type calcium channel blocker-1
T12153
Synonym:
Target: Calcium Channel
KCa2 channel modulator 1
T60985
Synonym:
Target:
M2 ion channel blocker
T11927
Synonym:
Target: Others
Cat No. Product Name Synonyms Targets
TN2275 Tinnevellin glucoside Others
Tinnevellin glucoside is a natural product from Cassia angustifolia.
TN5426 Sonnerphenolic B (+)-Sonnerphenolic B
Sonnerphenolic B is a natural product for research related to life sciences. The catalog number is TN5426 and the CAS number is 1627516-10-2.

Natural Products

Tinnevellin glucoside
TN2275
Synonym:
Target: Others
Sonnerphenolic B
TN5426
Synonym: (+)-Sonnerphenolic B
Target:

Recombinant Proteins

Species：
Human (5)
H3N2 (3)
H10N3 (2)
Lolium perenne (2)
H1N1 (1)
H1N2 (1)
Mouse (1)
Expression System：
E. coli (8)
HEK293 Cells (5)
Baculovirus Insect Cells (2)
Tag：
C-His (7)
His (2)
Tag Free (2)
N-10xHis, C-Myc (1)
N-10xHis-SUMO, C-Myc (1)
N-6xHis (1)
N-His (1)
Cat No. Product Name Species Expression System
TMPY-02412 ENO1 Protein, Human, Recombinant (His) Human E. coli
ENO1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 49.3 kDa and the accession number is P06733-1.
TMPH-02505 ENO1 Protein, Mouse, Recombinant (His) Mouse E. coli
Glycolytic enzyme the catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May ...
TMPY-02592 Annexin VI/ANXA6 Protein, Human, Recombinant (His) Human E. coli
Annexin A6, also known as ANXA6 or ANXAⅥ, belongs to a family of Ca2+-dependent membrane and phospholipid binding proteins. Members of this family have been implicated in membrane-related events along exocytotic and endo...
TMPY-05759 Annexin V/ANXA5 Protein, Human, Recombinant, Biotinylated Human E. coli
Annexin V/ANXA5 Protein, Human, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 35.9 kDa and the accession number is P08758.
TMPY-02540 Annexin V/ANXA5 Protein, Human, Recombinant Human E. coli
Annexin V/ANXA5 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 35.9 kDa and the accession number is P08758.
TMPY-05883 Influenza A H1N2 (A/Minnesota/14/2012) Hemagglutinin/HA Protein (His) H1N2 HEK293 Cells
Influenza A H1N2 (A/Minnesota/14/2012) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is X5FSZ1.
TMPY-02416 Influenza A H10N3 (A/mallard/Minnesota/Sg-00194/2007) Hemagglutinin/HA Protein (His) H10N3 Baculovirus Insect Cells
Influenza A H10N3 (A/mallard/Minnesota/Sg-00194/2007) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.9 kDa and the accession number is C6Y4Y2.
TMPY-00585 Annexin A8 Protein, Human, Recombinant (His) Human E. coli
We have previously shown that Annexin A8 (ANXA8) is strongly associated with the basal-like subgroup of breast cancers, including BRCA1-associated breast cancers, and poor prognosis; while in the mouse mammary gland AnxA...
TMPY-06471 Influenza A H3N2 (A/Minnesota/41/2019) Hemagglutinin/HA Protein (His) H3N2 HEK293 Cells
Influenza A H3N2 (A/Minnesota/41/2019) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.50 kDa.
TMPY-05869 Influenza A H1N1 (A/Swine/Minnesota/55551/2000) Hemagglutinin/HA Protein (His) H1N1 HEK293 Cells
Influenza A H1N1 (A/Swine/Minnesota/55551/2000) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.4 kDa and the accession number is Q8QT91.
TMPH-02411 Lol p 1 Protein, Lolium perenne, Recombinant (His & Myc) Lolium perenne E. coli
Lol p 1 Protein, Lolium perenne, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.2 kDa and the accession number is P14946.
TMPH-02410 Lol p 5a Protein, Lolium perenne, Recombinant (His & Myc & SUMO) Lolium perenne E. coli
Lol p 5a Protein, Lolium perenne, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 48.4 kDa and the accession number is Q40240.
TMPY-04837 Influenza A H3N2 (A/Johannesburg/33/1994) Hemagglutinin/HA Protein (His) H3N2 Baculovirus Insect Cells
Influenza A H3N2 (A/Johannesburg/33/1994) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.4 kDa and the accession number is I6TFC9.
TMPY-04744 Influenza A H3N2 (A/Johannesburg/33/1994) Hemagglutinin/HA1 Protein (His) H3N2 HEK293 Cells
Influenza A H3N2 (A/Johannesburg/33/1994) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.1 kDa and the accession number is I6TFC9.
TMPY-04186 Influenza A H10N3 (A/mallard/Minnesota/Sg-00194/2007) Hemagglutinin/HA1 Protein (His) H10N3 HEK293 Cells
Influenza A H10N3 (A/mallard/Minnesota/Sg-00194/2007) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.7 kDa and the accession number is C6Y4Y2.
ENO1 Protein, Human, Recombinant (His)
TMPY-02412
Species: Human
Expression System: E. coli
ENO1 Protein, Mouse, Recombinant (His)
TMPH-02505
Species: Mouse
Expression System: E. coli
Annexin VI/ANXA6 Protein, Human, Recombinant (His)
TMPY-02592
Species: Human
Expression System: E. coli
Annexin V/ANXA5 Protein, Human, Recombinant, Biotinylated
TMPY-05759
Species: Human
Expression System: E. coli
Annexin V/ANXA5 Protein, Human, Recombinant
TMPY-02540
Species: Human
Expression System: E. coli
Influenza A H1N2 (A/Minnesota/14/2012) Hemagglutinin/HA Protein (His)
TMPY-05883
Species: H1N2
Expression System: HEK293 Cells
Influenza A H10N3 (A/mallard/Minnesota/Sg-00194/2007) Hemagglutinin/HA Protein (His)
TMPY-02416
Species: H10N3
Expression System: Baculovirus Insect Cells
Annexin A8 Protein, Human, Recombinant (His)
TMPY-00585
Species: Human
Expression System: E. coli
Influenza A H3N2 (A/Minnesota/41/2019) Hemagglutinin/HA Protein (His)
TMPY-06471
Species: H3N2
Expression System: HEK293 Cells
Influenza A H1N1 (A/Swine/Minnesota/55551/2000) Hemagglutinin/HA Protein (His)
TMPY-05869
Species: H1N1
Expression System: HEK293 Cells
Lol p 1 Protein, Lolium perenne, Recombinant (His & Myc)
TMPH-02411
Species: Lolium perenne
Expression System: E. coli
Lol p 5a Protein, Lolium perenne, Recombinant (His & Myc & SUMO)
TMPH-02410
Species: Lolium perenne
Expression System: E. coli
Influenza A H3N2 (A/Johannesburg/33/1994) Hemagglutinin/HA Protein (His)
TMPY-04837
Species: H3N2
Expression System: Baculovirus Insect Cells
Influenza A H3N2 (A/Johannesburg/33/1994) Hemagglutinin/HA1 Protein (His)
TMPY-04744
Species: H3N2
Expression System: HEK293 Cells
Influenza A H10N3 (A/mallard/Minnesota/Sg-00194/2007) Hemagglutinin/HA1 Protein (His)
TMPY-04186
Species: H10N3
Expression System: HEK293 Cells
Cat No. Product Name
L7200 Calcium Channel Compound Library

140 compounds
A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;
L7300 Potassium Channel Blocker Library

152 compounds
A unique collection of 152 potassium channel blockers and agonists for high throughput and high content screening;
L2300 Ion Channel Inhibitor Library

931 compounds
A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
L7400 Sodium Channel Blocker Library

118 compounds
A unique collection of 118 sodium channel blockers and agonists for high throughput and high content screening;

Libraries

Calcium Channel Compound Library
L7200
Compounds: 140
Potassium Channel Blocker Library
L7300
Compounds: 152
Ion Channel Inhibitor Library
L2300
Compounds: 931
Sodium Channel Blocker Library
L7400
Compounds: 118
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