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Search Results for " m6 "

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T37645	Dasatinib metabolite M6
	Dasatinib metabolite M6 (Dasatinib carboxylic acid) is an oxidative metabolite of Dasatinib, a potent and orally active inhibitor of both Bcr-Abl and Src family tyrosine kinases[1].
T25225	Cephabacin M6	Cephabacin M(sub 6)
	Cephabacin M6 is a new cephem antibiotic isolated from bacterial.
T31055	CP-457493	OSI-493,Erlotinib metabolite M6,CP457493,UNII-X0JH558S7E
	CP-457493 is a bio-active chemical.
T29303	1M6	1M-6,1M 6,1-Methyl-6-nitroisatoic anhydride
	1M6 (1-Methyl-6-nitroisatoic anhydride) is a SHAPE reagent for the detection of RNA chemical structures.
T37292	M62812		TLR
	TLR4 inhibitor. Inhibits LPS-induced NF-κB activation in HEK293 cells (IC50 = 2.4 μg/mL). Also inhibits LPS-induced cytokine production and procoagulant effects in PBMCs and HUVECs. Prolongs survival in a mouse septic sh...		TLR
TP1993L	M617 acetate		Neuropeptide Y Receptor
	M617 acetate is a selective agonist of galanin receptor 1 (GAL1). M617 acetate acts through central GAL1, promotes GLUT4 expression, and enhances GLUT4 content in the cardiac muscle of type 2 diabetic rats. The Ki values...		Neuropeptide Y Receptor
T8649	TMBIM6 antagonist-1	BAX-inhibitor-1,BIA	mTOR
	TMBIM6 antagonist-1 (BAX-inhibitor-1) is a bax inhibitor		mTOR
T17105	TM6089		HIF/HIF Prolyl-Hydroxylase
	TM6089 is an inhibitor of Prolyl Hydroxylase that stimulates HIF activity without iron chelation, induces angiogenesis, and protects organ against ischemia.		HIF/HIF Prolyl-Hydroxylase
T26629	Angstrom6	A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide	PAI-1
	Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascade and abrogates the downstream effects.Angstrom6 has antitumor a...		PAI-1
T10896L	CSRM617 hydrochloride	CSRM617 hydrochloride(787504-88-5 Free base)	Apoptosis , Others , Androgen Receptor
	CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 ( OC2, a master regulator of androgen receptor) with a K d of 7.43 uM in SPR assays, directly binds to OC2-HOX domain. CSR...		Apoptosis , Others , Androgen Receptor
T62358	BM635 hydrochloride
	BM635 hydrochloride is an MmpL3 inhibitor that exhibits significant anti-Divergent bacteriophage effects, inhibiting the binding of Divergent bacteriophage H37Rv (MIC50: 0.08 μM). Exposure to BM635 hydrochloride was doub...
T63263	BM635 mesylate
	BM635 mesylate, an inhibitor of MmpL3, exhibited significant anti-Divergent bacterium effects, inhibiting and binding Divergent bacterium H37Rv with an MIC50 value of 0.6 μM. BM635 mesylate was able to significantly incr...
T10563L	BM635 hydrochloride (1493762-74-5 free base)	BM635 hydrochloride	Others
	BM635 hydrochloride is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).		Others
T10563	BM635		Others
	BM635 is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).		Others
T26281	TM6008	TM 6008,TM-6008
	TM6008 is an inhibitor of prolyl hydroxylase that protects against cell death after hypoxia.
T74474	M7Gpppm6AmpG ammonium
	M7Gpppm6AmpG ammonium, a trinucleotide mRNA 5’ cap analog, facilitates in vitro RNA synthesis [1].
T75817	M617 TFA
	M617 TFA, a selective galanin receptor 1 (GAL1) agonist, exhibits dissociation constants (Kis) of 0.23 nM for GAL1 and 5.71 nM for GAL2. Through activation of GAL1, M617 TFA enhances GLUT4 expression and content in the c...
TP1993	M617
	Selective galanin GAL1 receptor agonist (Ki values are 0.23 and 5.71 nM for GAL1 and GAL2 receptors respectively). Enhances food consumption in rats following i.c.v. administration and reduces CAP-induced inflammatory pa...
T22563	AM6545		Others
	CB1 selective neutral antagonist		Others
T71493	AM6580
	AM6580 is an irreversible monoacylglycerol lipase (MGL) inhibitor.
T63613	JM6
	JM6 is a weak kynurenine 3-monooxygenase (KMO) inhibitor that acts on mouse KMO (IC50: 19.85 μM). JM6 can be used to study Alzheimer's disease.
T28805	SLM6	NSC-107517,NSC 107517,Sangivamycin-Like Molecule 6,SLM 6,SLM-6
	SLM6, an inhibitor of cyclin-dependent kinase-9 (CDK9), exhibits potent anti-multiple myeloma activity.
T10896	CSRM617		Others
	CSRM617 is a selective small molecule inhibitor of the transcription factor ONECUT2 (OC2, the main regulator of androgen receptor). The Kd in SPR analysis is 7.43 uM, which can directly bind to the OC2-HOX domain. CSRM61...		Others
T10563L2	BM635 mesylate (1493762-74-5 free base)	BM635 mesylate	Others
	BM635 mesylate is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).		Others
T78561	M62812 free base
	M62812 (free base), a Toll-like receptor 4 (TLR4) signal transduction inhibitor, suppresses activation of endothelial cells and leukocytes and prevents lethal septic shock in mice. It is utilized in sepsis research [1].
T72020	AM6701
	AM6701 is a novel highly potent inhibitor of human alpha/beta hydrolase domain 6 (habhd6)
T28806	SLM6031434 HCl	SLM 6031434,SLM6031434,SLM-6031434
	SLM6031434 is selective inhibitor of SphK2.
T23826	BSBM6	BSBM 6,BSBM-6
	BSBM6 is an inhibitor of Aβ aggregation and neuronal toxicity that acts by reversing the aggregation and toxicity of amyloid-β peptides.
T73511	SZM679		RIP kinase
	SZM679 is an orally active, selective RIPK1 inhibitor displaying potent affinity with a dissociation constant (Kd) of 8.6 nM for RIPK1, while exhibiting minimal activity towards RIPK3, with a Kd of >5000 nM. It effective...		RIP kinase
T28545	RM65
	RM65 is an arginine methyltransferase inhibitor.
T19405	LOM612		Others
	LOM612 is a potent FOXO relocator, with an EC50 value of 1.5 μM in U2fox RELOC cells.		Others
T33138	M6407
	M6407 is a bioactive chemical.
T34892	TM608	TM-608,TM 608
	TM608 is a potent selective c-Met inhibitor that targets mitochondria and kills erlotinib-resistant lung cancer cells, rapidly accumulates in mitochondria, and inhibits MET activation in high MET expression, erlotinib-re...
T74473	M7Gpppm6AmpG
	m7Gpppm6AmpG, a trinucleotide mRNA 5’ cap analog, facilitates RNA synthesis in vitro [1].
T80396	Im6
	Im6, an antimicrobial peptide, exhibits activity against Gram-positive bacteria, specifically S. aureus and B. subtilis [1].
T81891	M65
	M65 is a PAC1 receptor-specific antagonist that inhibits the secretion of atrial natriuretic peptide (ANP) [1].
T14205	AM679		Others
	AM679 is a potent and selective FLAP inhibitor with IC50s of 2.2 nM/0.6 nM/154 nM for FLAP binding/hLA/hWB respectively. IC50 value: 2.2 nM/0.6 nM/154 nM(FLAP binding/hLA/hWB) [1] AM679 showed an improved CYP inhibition ...		Others
T70071	SLM6031434 (free base)
	SLM6031434 (free base) is an inhibitor of sphingosine kinase type 2 (SphK2). It consists of pedant 1-guanidino-2-phenyloxadiazolylpyrrolidine group.

Compounds

Dasatinib metabolite M6

Synonym: Cephabacin M(sub 6)

Target:

CP-457493

T31055

Synonym: OSI-493,Erlotinib metabolite M6,CP457493,UNII-X0JH558S7E

Target:

1M6

T29303

Synonym: 1M-6,1M 6,1-Methyl-6-nitroisatoic anhydride

Target: Neuropeptide Y Receptor

TMBIM6 antagonist-1

T8649

Synonym: BAX-inhibitor-1,BIA

Target: HIF/HIF Prolyl-Hydroxylase

Angstrom6

T26629

Synonym: A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide

Target: PAI-1

CSRM617 hydrochloride

T10896L

Synonym: CSRM617 hydrochloride(787504-88-5 Free base)

Target: Apoptosis, Others, Androgen Receptor

BM635 hydrochloride (1493762-74-5 free base)

T10563L

Synonym: BM635 hydrochloride

Synonym: TM 6008,TM-6008

Target:

m7Gpppm6AmpG ammonium

Synonym: NSC-107517,NSC 107517,Sangivamycin-Like Molecule 6,SLM 6,SLM-6

BM635 mesylate (1493762-74-5 free base)

T10563L2

Synonym: BM635 mesylate

Synonym: SLM 6031434,SLM6031434,SLM-6031434

Target:

BSBM6

T23826

Synonym: BSBM 6,BSBM-6

Synonym: TM-608,TM 608

SLM6031434 (free base)

T70071

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
T8878	Urolithin M6	3,8,9,10-tetrahydroxy urolithin	Others
	urolithin M6 (3,8,9,10-tetrahydroxy urolithin) (UM6) is an ellagitannin metabolite produced by gut microbiota, was identified as a putative galloflavin mimetic		Others

Natural Products

urolithin M6

T8878

Synonym: 3,8,9,10-tetrahydroxy urolithin

Target: Others

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPK-01334	EMMPRIN/CD147 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation of extracellular matrix (ECM) remodeling during physiolo...
TMPH-00797	HopQ Protein, Helicobacter pylori Hp M6, Recombinant (His & Myc)	Helicobacter pylori Hp M6	E. coli
	HopQ Protein, Helicobacter pylori Hp M6, Recombinant (His & Myc) is expressed in E. coli.
TMPY-00684	EMMPRIN/CD147 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	EMMPRIN/CD147 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is P35613-2.
TMPY-00685	EMMPRIN/CD147 Protein, Human, Recombinant	Human	HEK293 Cells
	EMMPRIN/CD147 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.7 kDa and the accession number is P35613-2.
TMPH-00998	CD147 Protein, Human, Recombinant (aa 138-323, hFc)	Human	HEK293 Cells
	CD147 Protein, Human, Recombinant (aa 138-323, hFc) is expressed in HEK293.
TMPJ-00160	EMMPRIN/CD147 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane ...
TMPY-05850	CEACAM6 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	CEACAM6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.3 kDa and the accession number is XP_005589488.1.
TMPY-00971	CEACAM6 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CEACAM6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.6 kDa and the accession number is P40199.
TMPY-06758	CEACAM6 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	CEACAM6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 34.47 kDa and the accession number is NP_002474.3.
TMPY-06760	CEACAM6 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CEACAM6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.94 kDa and the accession number is NP_002474.3.
TMPK-00232	CEACAM6 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) belongs to the human carcino-embryonic antigen (CEA) family. Numerous lines of studies have indicated that altered expression of CEACAM6 may have a role...
TMPK-01311	CEACAM6 Protein, Cynomolgus, Recombinant (aa 35-320, His)	Cynomolgus	HEK293 Cells
	Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) belongs to the human carcino-embryonic antigen (CEA) family. Numerous lines of studies have indicated that altered expression of CEACAM6 may have a role...
TMPH-02634	TRIM63 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein...
TMPY-05460	CEACAM6 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	CEACAM6 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.6 kDa and the accession number is P40199.
TMPK-00233	CEACAM6 Protein, Human, Recombinant (aa 35-320, His & Avi), Biotinylated	Human	HEK293 Cells
	Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) belongs to the human carcino-embryonic antigen (CEA) family. Numerous lines of studies have indicated that altered expression of CEACAM6 may have a role...
TMPH-03282	TRIM63 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein...
TMPH-01271	TRIM63 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein...
TMPY-00150	IGF2/IGF-II Protein, Human, Recombinant	Human	P. pastoris (Yeast)
	Insulin-like growth factor 2 (IGF-2/IGF-II) is a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele,...