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Search Result

Search Results for " lpg "

Targets

Androgen Receptor

14

Compounds

8

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T11410L GLPG0492 Androgen Receptor
GLPG0492 is a novel selective androgen receptor modulator. After oral dosing, it showed anabolic activity on muscle, strongly dissociated from the androgenic activity on the prostate.
T4259 GLPG0187 Integrin
GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).
T11411 GLPG1205 GPR , Others
GLPG1205 is a potent, orally active GPR84 (G protein-coupled receptor) antagonist with anti-inflammatory activity. GLPG1205 shows good PK/PD characteristics and can be used to study pulmonary fibrosis.
T7083 GLPG1837 ABBV-974 CFTR , Autophagy
GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.
T3076 GLPG0634 analog GLPG0634 analogue Tyrosine Kinases , JAK
GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.
T15388 GLPG0974 GLPG-0974 GPR
GLPG0974 is an antagonist of FFA2/GPR43 with IC50 of 9 nM.
T9199 GLPG2938 1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea S1P Receptor , LPL Receptor
GLPG2938 (1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea) is a potent and selective antagonist of S1P2.
T75113 GLPG2534 GLPG-2534 IRAK
GLPG2534 is an orally active, selective and potent IRAK4 inhibitor with anti-inflammatory activity. GLPG2534 inhibits human and mouse IRAK4 and could be used to study psoriasis and atopic dermatitis.
T11410 GLPG0492 (R enantiomer) GLPG0492 R enantiomer Others
GLPG0492 R enantiomer is the R enantiomer of GLPG-0492, a novel selective androgen receptor modulator.
T13704 GLPG-3221 Others
GLPG-3221 can be uesd for the treatment of cystic fibrosis.GLPG-3221 is a potent, orally active corrector of CFTR (cystic fibrosis transmembrane conductance regulator), with an EC50 of 105 nM.
T27416 GLPG0259 GLPG-0259,GLPG 0259
GLPG-0259 is an inhibitor of mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5).
T13705 GLPG2451 Cysteine Protease
GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. It effectively potentiates low temperature rescued F508del CFTR (EC50: 11.1 nM).
T71274 GLPG0259 A
GLPG0259 A is a small-molecule inhibitor of mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), a kinase enzyme that plays a role in important inflammatory pathways.
T73384 GLPG3970
GLPG3970, a pioneering inhibitor of SIK2/SIK3, is utilized in the investigation of inflammation and autoimmune diseases.

Recombinant Proteins

Species：
Human (6)
Mouse (1)
Rat (1)
Expression System：
HEK293 (6)
E. coli (2)
Tag：
C-His (3)
His,Trx (2)
C-His-Avi (1)
C-hFc (1)
C-mFc (1)
Cat No. Product Name Species Expression System
TMPY-05297 Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx) Human E. coli
Apolipoprotein E (ApoE) is a 34.2 kDa glycosylated protein with 299 amino acid residues. There are three isoforms in human (apoE2, apoE3, and apoE4) due to different amino acid residues at positions 112 and 158. ApoE is ...
TMPY-05528 Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated Human E. coli
Apolipoprotein E (ApoE) is a 34.2 kDa glycosylated protein with 299 amino acid residues. There are three isoforms in human (apoE2, apoE3, and apoE4) due to different amino acid residues at positions 112 and 158. ApoE is ...
TMPK-00639 Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His) Rat HEK293
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ...
TMPK-00803 Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His) Human HEK293
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ...
TMPK-00802 Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (hFc) Human HEK293
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ...
TMPK-00801 Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ...
TMPK-00804 Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (mFc) Human HEK293
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ...
TMPK-00855 Alkaline Phosphatase (Germ type) /ALPG Protein, Mouse, Recombinant (His) Mouse HEK293
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ...
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