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Catalog No. T9199   CAS 2130996-00-6
Synonyms: 1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea

GLPG2938 is a potent and selective antagonist of S1P2.

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GLPG2938, CAS 2130996-00-6
Pack Size Availability Price/USD Quantity
1 mg In stock $ 76.00
5 mg In stock $ 163.00
10 mg In stock $ 289.00
25 mg In stock $ 578.00
50 mg In stock $ 833.00
100 mg In stock $ 1,150.00
1 mL * 10 mM (in DMSO) In stock $ 179.00
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Purity: 98.1%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description GLPG2938 is a potent and selective antagonist of S1P2.
In vitro GLPG2938 significantly prevents the S1P-mediated contraction at all tested concentrations[1].
In vivo In all species ,GLPG2938 shows good pharmacokinetics, with long half-life,low clearance,and good bioavailability.
Synonyms 1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea
Molecular Weight 503.4
Formula C20H19F6N7O2
CAS No. 2130996-00-6


Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

DMSO: 60 mg/ml (119.19 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Discovery of the S1P2 Antagonist GLPG2938 (1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a Preclinical Candidate for the Treatment of Idiopathic Pulmonary Fibrosis[J]. Journal of Medicinal Chemistry, 2021, 64(9):6037-6058.

Related compound libraries

This product is contained In the following compound libraries:
Inhibitor Library Bioactive Compound Library Bioactive Compounds Library Max GPCR Compound Library NO PAINS Compound Library

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GLPG2938 2130996-00-6 GPCR/G Protein S1P Receptor LPL Receptor GLPG 2938 Lysophospholipid Receptor fibrosis inhibit 1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea GLPG-2938 selective pulmonary Inhibitor potent idiopathic inhibitor