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Search Results for " interferon-γ "

Targets

13

Compounds

3

Natural Products

41

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T4403 AX-024 hydrochloride AX-024 HCl IL Receptor , TNF , COX , IFNAR , Interleukin
AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
T76742 Emapalumab NI-0501 COX
Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab ha...
T26895 BRD0476 BRD-0476,ML 187,ML187,ML-187,BRD 0476
BRD0476 is a suppressor of pancreatic β-cell apoptosis. BRD0476 inhibits interferon-gamma (IFN-γ)-induced Janus kinase 2 (JAK2) and signal transducer and activation of transcription 1 (STAT1) signaling to promote β-cell ...
T76637 IFN-γ Antagonist 1
IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI), an interferon γ (IFN γ) antagonist, effectively inhibits IFN-γ induced HLR/DR antigen expression in Colon 205 cells, demonstrating an IC50 of approximately 35 μM. This compoun...
T76638 IFN-γ Antagonist 1 acetate
IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) acetate, an interferon γ (IFN γ) antagonist, effectively inhibits the expression of HLR/DR antigen in Colon 205 cells induced by IFN-γ, with an inhibition concentration (IC 50)...
T81331 QL-1200186 JAK
QL-1200186 is an orally active, selective TYK2 inhibitor that, upon dose-dependent oral administration, suppresses interferon-γ (IFNγ) production following interleukin-12 (IL-12) stimulation and markedly improves skin le...
T70291 PCC0208018
PCC0208018 is a novel activator of effector T cells, enhancing T cell proliferation and activation to release interferon gamma (IFN-γ) and interleukin-2 (IL-2) without blocking the programmed cell death 1 (PD-1)/programm...
T77003 Ezabenlimab
Ezabenlimab (BI-754091) is an anti-PD-1 monoclonal antibody (mAb) that exhibits a binding constant (Kd) of 6 nM in CHO cells. It effectively inhibits the interaction between PD-1 and its ligands, PD-L1 and PD-L2, enhanci...
T61574 PD-L1-IN-1
PD-L1-IN-1, a powerful PD-L1 inhibitor, demonstrated an IC50 of 115 nM. By forming a robust bond with the PD-L1 protein, PD-L1-IN-1 effectively suppressed tumor growth by enhancing the antitumor immune activity of periph...
T81697 NBI-6024
NBI-6024, an altered peptide ligand (APL), serves as an epitope for interferon-gamma-producing T helper lymphocytes associated with inflammation in patients with type 1 diabetes [1] [2].
T83846 HOXB7 (8-25) TFA Homeobox B7 (8-25)
HOXB7 (8-25), a peptide fragment derived from homeobox B7 (HOXB7)—a key controller of cell growth and oncogene activator—facilitates antigen presentation when pulsed onto dendritic cells obtained from human peripheral bl...
T61968 PD-1/PD-L1-IN 6
PD-1/PD-L1-IN 6 (compound A13) is a potent inhibitor of PD-1/PD-L1 interaction (IC 50 = 132.8 nM). PD-1/PD-L1-IN 6 shows outstanding immunoregulatory activity. In a Hep3B/OS-8/hPD-L1 and CD3 T cell co-culture model, PD-1...
T82071 Influenza NP (311-325)
Influenza NP (311-325) is a biologically active peptide composed of amino acids 311 to 325 derived from the influenza virus nucleoprotein (NP). As a bona fide MHC class II-restricted epitope, it is instrumental for study...
Cat No. Product Name Synonyms Targets
TQ0273 Neopterin D-(+)-Neopterin,2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one Endogenous Metabolite
D-(+)-Neopterin (D-(+)-Neopterin) is produced by human monocytes/macrophages upon stimulation with the cytokine interferon-γ. In humans, neopterin is involved in purine biosynthesis.
T14854 Caerulomycin A Cerulomycin,Caerulomycin Antifungal
Caerulomycin A (Caerulomycin) (Cerulomycin; Caerulomycin) is an antifungal compound. Which induces generation of T cells, enhances TGF-β-Smad3 protein signaling via suppressing interferon-γ-induced STAT1 signaling. Antif...
T5681 ETHYL CAFFEATE ETHYL 3,4-DIHYDROXYCINNAMATE NF-κB , COX , PGE Synthase , NO Synthase
Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro. Furthermore, Ethyl Caffeate intensely blocked the transcriptional expression in interferon-γ-related s...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPK-00047 IFN gamma Protein, Human, Recombinant (His & Avi) Human HEK293
Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experi...
TMPY-02827 IFN gamma Protein, Rat, Recombinant (hFc) Rat HEK293
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-01714 IFN gamma Protein, Human, Recombinant Human CHO
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-03356 IFN gamma Protein, Mouse, Recombinant Mouse HEK293
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-06983 IFN gamma Protein, Human, Recombinant (E. coli) Human E. coli
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-01151 IFNGR1 Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-02355 IFNGR1 Protein, Mouse, Recombinant (His) Mouse HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPK-00048 IFN gamma Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experi...
TMPY-04191 IFN gamma Protein, Rhesus, Recombinant (His) Rhesus HEK293
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-03664 IFN gamma Protein, Ferret, Recombinant (His) Ferret HEK293
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-00527 IFN gamma Protein, Rhesus, Recombinant Rhesus E. coli
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-02323 IFN gamma Protein, Mouse, Recombinant (His) Mouse HEK293
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-02322 IFN gamma Protein, Mouse, Recombinant (hFc) Mouse HEK293
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-03379 IFNGR1 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03346 IFNGR1 Protein, Rat, Recombinant (hFc) Rat HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03668 IFNGR1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-02122 IFNGR2 Protein, Mouse, Recombinant (His) Mouse HEK293
Interferon-gamma receptor beta chain (IFNgammaR2), also known as IFNGR2, belongs to the type II cytokine receptor family, whose deficiency is a cause of autosomal recessive mendelian susceptibility to mycobacterial disea...
TMPY-05831 IFNGR1 Protein, Human, Recombinant (hFc) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPJ-01056 IL-18 Protein, Mouse, Recombinant (His) Mouse E. coli
Interleukin-18 (IL-18)is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63...
TMPJ-00884 CXCL9 Protein, Mouse, Recombinant (His) Mouse Human Cells
Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family. CXCL9 functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor foun...
TMPY-02354 IFNGR1 Protein, Mouse, Recombinant (hFc) Mouse HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPJ-01084 CXCL9 Protein, Human, Recombinant (His) Human Human Cells
Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages and endothelial cells, which elicits chemotactic functions b...
TMPY-02887 IFI30 Protein, Human, Recombinant (His) Human HEK293
IFI30 belongs to the GILT family. This family includes the two characterized human gamma-interferon-inducible lysosomal thiol reductase (GILT) sequences: P13284 and Q9UL08. It also contains several other eukaryotic putat...
TMPJ-00070 IL-18 Protein, Human, Recombinant (His) Human Human Cells
Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The c...
TMPJ-00008 CXCL10 Protein, Human, Recombinant (hFc & His) Human Human Cells
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CX...
TMPJ-00072 IL-18BPd Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF-γ, which then stimulates 18BP production via NF-κB. The interact...
TMPY-03945 Latent TGF beta 1 Protein, Rat, Recombinant (His) Rat HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-04211 Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00608 TGF beta 1 Protein, Rat/Mouse, Recombinant Mouse,Rat HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00500 Latent TGF beta 1 Protein, Mouse, Recombinant (His) Mouse HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-01133 Latent TGF beta 1 Protein, Human, Recombinant (His) Human HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-02638 TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant Human,Rhesus,Cynomolgus,Canine CHO
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPK-00237 2B4/CD244 Protein, Human, Recombinant (aa 22-221, His & Avi), Biotinylated Human HEK293
2B4 (CD244) is expressed by memory-phenotype CD8() T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 is conserved in humans and mice, and a number of reports ha...
TMPY-03667 SLAM/CD150 Protein, Rat, Recombinant (His) Rat HEK293
CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is exp...
TMPY-00627 SLAM/CD150 Protein, Rat, Recombinant (hFc) Rat HEK293
CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is exp...
TMPY-01016 SLAM/CD150 Protein, Human, Recombinant (His) Human HEK293
CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is exp...
TMPY-05528 Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated Human E. coli
Apolipoprotein E (ApoE) is a 34.2 kDa glycosylated protein with 299 amino acid residues. There are three isoforms in human (apoE2, apoE3, and apoE4) due to different amino acid residues at positions 112 and 158. ApoE is ...
TMPY-05297 Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx) Human E. coli
Apolipoprotein E (ApoE) is a 34.2 kDa glycosylated protein with 299 amino acid residues. There are three isoforms in human (apoE2, apoE3, and apoE4) due to different amino acid residues at positions 112 and 158. ApoE is ...
TMPY-05521 Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated Human HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-05313 Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00229 Latent TGF beta 1 Protein, Canine, Recombinant (His) Canine HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
IFN gamma Protein, Human, Recombinant (His & Avi)
TMPK-00047
Species: Human
Expression System: HEK293
IFN gamma Protein, Rat, Recombinant (hFc)
TMPY-02827
Species: Rat
Expression System: HEK293
IFN gamma Protein, Human, Recombinant
TMPY-01714
Species: Human
Expression System: CHO
IFN gamma Protein, Mouse, Recombinant
TMPY-03356
Species: Mouse
Expression System: HEK293
IFN gamma Protein, Human, Recombinant (E. coli)
TMPY-06983
Species: Human
Expression System: E. coli
IFNGR1 Protein, Human, Recombinant (His)
TMPY-01151
Species: Human
Expression System: HEK293
IFNGR1 Protein, Mouse, Recombinant (His)
TMPY-02355
Species: Mouse
Expression System: HEK293
IFN gamma Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00048
Species: Human
Expression System: HEK293
IFN gamma Protein, Rhesus, Recombinant (His)
TMPY-04191
Species: Rhesus
Expression System: HEK293
IFN gamma Protein, Ferret, Recombinant (His)
TMPY-03664
Species: Ferret
Expression System: HEK293
IFN gamma Protein, Rhesus, Recombinant
TMPY-00527
Species: Rhesus
Expression System: E. coli
IFN gamma Protein, Mouse, Recombinant (His)
TMPY-02323
Species: Mouse
Expression System: HEK293
IFN gamma Protein, Mouse, Recombinant (hFc)
TMPY-02322
Species: Mouse
Expression System: HEK293
IFNGR1 Protein, Cynomolgus, Recombinant (hFc)
TMPY-03379
Species: Cynomolgus
Expression System: HEK293
IFNGR1 Protein, Rat, Recombinant (hFc)
TMPY-03346
Species: Rat
Expression System: HEK293
IFNGR1 Protein, Cynomolgus, Recombinant (His)
TMPY-03668
Species: Cynomolgus
Expression System: HEK293
IFNGR2 Protein, Mouse, Recombinant (His)
TMPY-02122
Species: Mouse
Expression System: HEK293
IFNGR1 Protein, Human, Recombinant (hFc)
TMPY-05831
Species: Human
Expression System: HEK293
IL-18 Protein, Mouse, Recombinant (His)
TMPJ-01056
Species: Mouse
Expression System: E. coli
CXCL9 Protein, Mouse, Recombinant (His)
TMPJ-00884
Species: Mouse
Expression System: Human Cells
IFNGR1 Protein, Mouse, Recombinant (hFc)
TMPY-02354
Species: Mouse
Expression System: HEK293
CXCL9 Protein, Human, Recombinant (His)
TMPJ-01084
Species: Human
Expression System: Human Cells
IFI30 Protein, Human, Recombinant (His)
TMPY-02887
Species: Human
Expression System: HEK293
IL-18 Protein, Human, Recombinant (His)
TMPJ-00070
Species: Human
Expression System: Human Cells
CXCL10 Protein, Human, Recombinant (hFc & His)
TMPJ-00008
Species: Human
Expression System: Human Cells
IL-18BPd Protein, Mouse, Recombinant (hFc)
TMPJ-00072
Species: Mouse
Expression System: Human Cells
Latent TGF beta 1 Protein, Rat, Recombinant (His)
TMPY-03945
Species: Rat
Expression System: HEK293
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)
TMPY-04211
Species: Cynomolgus
Expression System: HEK293
TGF beta 1 Protein, Rat/Mouse, Recombinant
TMPY-00608
Species: Mouse,Rat
Expression System: HEK293
Latent TGF beta 1 Protein, Mouse, Recombinant (His)
TMPY-00500
Species: Mouse
Expression System: HEK293
Latent TGF beta 1 Protein, Human, Recombinant (His)
TMPY-01133
Species: Human
Expression System: HEK293
TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant
TMPY-02638
Species: Human,Rhesus,Cynomolgus,Canine
Expression System: CHO
2B4/CD244 Protein, Human, Recombinant (aa 22-221, His & Avi), Biotinylated
TMPK-00237
Species: Human
Expression System: HEK293
SLAM/CD150 Protein, Rat, Recombinant (His)
TMPY-03667
Species: Rat
Expression System: HEK293
SLAM/CD150 Protein, Rat, Recombinant (hFc)
TMPY-00627
Species: Rat
Expression System: HEK293
SLAM/CD150 Protein, Human, Recombinant (His)
TMPY-01016
Species: Human
Expression System: HEK293
Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated
TMPY-05528
Species: Human
Expression System: E. coli
Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx)
TMPY-05297
Species: Human
Expression System: E. coli
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated
TMPY-05521
Species: Human
Expression System: HEK293
Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated
TMPY-05313
Species: Mouse
Expression System: HEK293
Latent TGF beta 1 Protein, Canine, Recombinant (His)
TMPY-00229
Species: Canine
Expression System: HEK293
TargetMol