13
3
41
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4403 | AX-024 hydrochloride | AX-024 HCl | IL Receptor , TNF , COX , IFNAR , Interleukin |
AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A. | |||
T76742 | Emapalumab | NI-0501 | COX |
Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab ha... | |||
T26895 | BRD0476 | BRD-0476,ML 187,ML187,ML-187,BRD 0476 | |
BRD0476 is a suppressor of pancreatic β-cell apoptosis. BRD0476 inhibits interferon-gamma (IFN-γ)-induced Janus kinase 2 (JAK2) and signal transducer and activation of transcription 1 (STAT1) signaling to promote β-cell ... | |||
T76637 | IFN-γ Antagonist 1 | ||
IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI), an interferon γ (IFN γ) antagonist, effectively inhibits IFN-γ induced HLR/DR antigen expression in Colon 205 cells, demonstrating an IC50 of approximately 35 μM. This compoun... | |||
T76638 | IFN-γ Antagonist 1 acetate | ||
IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) acetate, an interferon γ (IFN γ) antagonist, effectively inhibits the expression of HLR/DR antigen in Colon 205 cells induced by IFN-γ, with an inhibition concentration (IC 50)... | |||
T81331 | QL-1200186 | JAK | |
QL-1200186 is an orally active, selective TYK2 inhibitor that, upon dose-dependent oral administration, suppresses interferon-γ (IFNγ) production following interleukin-12 (IL-12) stimulation and markedly improves skin le... | |||
T70291 | PCC0208018 | ||
PCC0208018 is a novel activator of effector T cells, enhancing T cell proliferation and activation to release interferon gamma (IFN-γ) and interleukin-2 (IL-2) without blocking the programmed cell death 1 (PD-1)/programm... | |||
T77003 | Ezabenlimab | ||
Ezabenlimab (BI-754091) is an anti-PD-1 monoclonal antibody (mAb) that exhibits a binding constant (Kd) of 6 nM in CHO cells. It effectively inhibits the interaction between PD-1 and its ligands, PD-L1 and PD-L2, enhanci... | |||
T61574 | PD-L1-IN-1 | ||
PD-L1-IN-1, a powerful PD-L1 inhibitor, demonstrated an IC50 of 115 nM. By forming a robust bond with the PD-L1 protein, PD-L1-IN-1 effectively suppressed tumor growth by enhancing the antitumor immune activity of periph... | |||
T81697 | NBI-6024 | ||
NBI-6024, an altered peptide ligand (APL), serves as an epitope for interferon-gamma-producing T helper lymphocytes associated with inflammation in patients with type 1 diabetes [1] [2]. | |||
T83846 | HOXB7 (8-25) TFA | Homeobox B7 (8-25) | |
HOXB7 (8-25), a peptide fragment derived from homeobox B7 (HOXB7)—a key controller of cell growth and oncogene activator—facilitates antigen presentation when pulsed onto dendritic cells obtained from human peripheral bl... | |||
T61968 | PD-1/PD-L1-IN 6 | ||
PD-1/PD-L1-IN 6 (compound A13) is a potent inhibitor of PD-1/PD-L1 interaction (IC 50 = 132.8 nM). PD-1/PD-L1-IN 6 shows outstanding immunoregulatory activity. In a Hep3B/OS-8/hPD-L1 and CD3 T cell co-culture model, PD-1... | |||
T82071 | Influenza NP (311-325) | ||
Influenza NP (311-325) is a biologically active peptide composed of amino acids 311 to 325 derived from the influenza virus nucleoprotein (NP). As a bona fide MHC class II-restricted epitope, it is instrumental for study... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TQ0273 | Neopterin | D-(+)-Neopterin,2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one | Endogenous Metabolite |
D-(+)-Neopterin (D-(+)-Neopterin) is produced by human monocytes/macrophages upon stimulation with the cytokine interferon-γ. In humans, neopterin is involved in purine biosynthesis. | |||
T14854 | Caerulomycin A | Cerulomycin,Caerulomycin | Antifungal |
Caerulomycin A (Caerulomycin) (Cerulomycin; Caerulomycin) is an antifungal compound. Which induces generation of T cells, enhances TGF-β-Smad3 protein signaling via suppressing interferon-γ-induced STAT1 signaling. Antif... | |||
T5681 | ETHYL CAFFEATE | ETHYL 3,4-DIHYDROXYCINNAMATE | NF-κB , COX , PGE Synthase , NO Synthase |
Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro. Furthermore, Ethyl Caffeate intensely blocked the transcriptional expression in interferon-γ-related s... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00047 | IFN gamma Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experi... | |||
TMPY-02827 | IFN gamma Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
TMPY-01714 | IFN gamma Protein, Human, Recombinant | Human | CHO |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
TMPY-03356 | IFN gamma Protein, Mouse, Recombinant | Mouse | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
TMPY-06983 | IFN gamma Protein, Human, Recombinant (E. coli) | Human | E. coli |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
TMPY-01151 | IFNGR1 Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-02355 | IFNGR1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPK-00048 | IFN gamma Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experi... | |||
TMPY-04191 | IFN gamma Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
TMPY-03664 | IFN gamma Protein, Ferret, Recombinant (His) | Ferret | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
TMPY-00527 | IFN gamma Protein, Rhesus, Recombinant | Rhesus | E. coli |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
TMPY-02323 | IFN gamma Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
TMPY-02322 | IFN gamma Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
TMPY-03379 | IFNGR1 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-03346 | IFNGR1 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-03668 | IFNGR1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-02122 | IFNGR2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Interferon-gamma receptor beta chain (IFNgammaR2), also known as IFNGR2, belongs to the type II cytokine receptor family, whose deficiency is a cause of autosomal recessive mendelian susceptibility to mycobacterial disea... | |||
TMPY-05831 | IFNGR1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPJ-01056 | IL-18 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Interleukin-18 (IL-18)is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63... | |||
TMPJ-00884 | CXCL9 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family. CXCL9 functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor foun... | |||
TMPY-02354 | IFNGR1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPJ-01084 | CXCL9 Protein, Human, Recombinant (His) | Human | Human Cells |
Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages and endothelial cells, which elicits chemotactic functions b... | |||
TMPY-02887 | IFI30 Protein, Human, Recombinant (His) | Human | HEK293 |
IFI30 belongs to the GILT family. This family includes the two characterized human gamma-interferon-inducible lysosomal thiol reductase (GILT) sequences: P13284 and Q9UL08. It also contains several other eukaryotic putat... | |||
TMPJ-00070 | IL-18 Protein, Human, Recombinant (His) | Human | Human Cells |
Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The c... | |||
TMPJ-00008 | CXCL10 Protein, Human, Recombinant (hFc & His) | Human | Human Cells |
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CX... | |||
TMPJ-00072 | IL-18BPd Protein, Mouse, Recombinant (hFc) | Mouse | Human Cells |
Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF-γ, which then stimulates 18BP production via NF-κB. The interact... | |||
TMPY-03945 | Latent TGF beta 1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPY-04211 | Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPY-00608 | TGF beta 1 Protein, Rat/Mouse, Recombinant | Mouse,Rat | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPY-00500 | Latent TGF beta 1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPY-01133 | Latent TGF beta 1 Protein, Human, Recombinant (His) | Human | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPY-02638 | TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant | Human,Rhesus,Cynomolgus,Canine | CHO |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPK-00237 | 2B4/CD244 Protein, Human, Recombinant (aa 22-221, His & Avi), Biotinylated | Human | HEK293 |
2B4 (CD244) is expressed by memory-phenotype CD8() T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 is conserved in humans and mice, and a number of reports ha... | |||
TMPY-03667 | SLAM/CD150 Protein, Rat, Recombinant (His) | Rat | HEK293 |
CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is exp... | |||
TMPY-00627 | SLAM/CD150 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is exp... | |||
TMPY-01016 | SLAM/CD150 Protein, Human, Recombinant (His) | Human | HEK293 |
CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is exp... | |||
TMPY-05528 | Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated | Human | E. coli |
Apolipoprotein E (ApoE) is a 34.2 kDa glycosylated protein with 299 amino acid residues. There are three isoforms in human (apoE2, apoE3, and apoE4) due to different amino acid residues at positions 112 and 158. ApoE is ... | |||
TMPY-05297 | Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx) | Human | E. coli |
Apolipoprotein E (ApoE) is a 34.2 kDa glycosylated protein with 299 amino acid residues. There are three isoforms in human (apoE2, apoE3, and apoE4) due to different amino acid residues at positions 112 and 158. ApoE is ... | |||
TMPY-05521 | Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPY-05313 | Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated | Mouse | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPY-00229 | Latent TGF beta 1 Protein, Canine, Recombinant (His) | Canine | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... |