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Search Results for " ip3 "

18

Compounds

Cat No. Product Name Synonyms Targets
T30935 Ci-IP3/PM
CI-IP3 /PM is a cell-permeable caged inositol triphosphate that promotes the release of Ca2+ from internal storage under UV photolysis.
T19266 Ins(1,4,5)-P3 hexapotassium salt 1,4,5-IP3 hexapotassium salt,D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt Others
D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt is promotes endoplasmic The second messenger of net calcium ions.
T8867 RO2959 Hydrochloride RO2959 HCl IL Receptor , Calcium Channel , Interleukin
RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
T41181 iP300v
iP300v is a negative control for iP300w
T83733 TIP39 (human, bovine) TFA Tuberoinfundibular Peptide of 39 Residues
TIP39, a neuropeptide and an agonist for the parathyroid hormone receptor type 2 (PTH2R), effectively increases cAMP levels in COS-7 cells featuring recombinant PTH2R from humans or rats (EC50s = 0.5 and 0.8 nM, respecti...
T68759 OSIP339391
OSIP339391 is a A2BAR antagonist.
T4693 2-Aminoethyl diphenylborinate 2-Aminoethoxydiphenyl borate,2-APB Calcium Channel , TRP/TRPV Channel
2-Aminoethyl diphenylborinate (2-APB) is a chemical that acts to inhibit both IP3 receptors and TRP channels (although it activates TRPV1, TRPV2, & TRPV3 at higher concentrations).
T11137 (E)-GABAB receptor antagonist 1 GABA Receptor
(E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM. GABAB receptor antagonist 1 is ...
T9031 MCU-i4 Others , Mitochondrial Metabolism
MCU-i4 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth.
T7190 Actein Apoptosis , Akt , JNK , Autophagy
Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein's ability to pathways in...
T23538 Xestospongin C (-)-Xestospongin C Others
IP3-dependent Ca2+ release inhibitor
TP1710 Calmodulin Binding Peptide 1
Calmodulin Binding Peptide 1, a potent CaM-binding peptide with picomolar (pM) affinity, originates from smooth muscle myosin light-chain kinase (MLCK peptide). It effectively blocks inositol trisphosphate (IP3)-induced ...
T14202 AM-4668 GPR
AM-4668 is a type 2 diabetes GPR40 agonist. For GPR40, in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), the EC50s are 3.6 nM and 36 nM, respectively.
T83950 ARN 11391
ARN 11391 enhances the function of the IP3-gated calcium channel ITPR1 (Inositol 1,4,5-trisphosphate (IP3) receptor type 1), boosting intracellular calcium ion signaling by directly targeting ITPR1. Furthermore, ARN 1139...
T11350 GABAB receptor antagonist 1 GABA Receptor
(E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric ac...
T37030 PtdIns-(4)-P1 (1,2-dioctanoyl) (ammonium salt) PtdIns-(4)-P1 (1,2-dioctanoyl) (ammonium salt)
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4)-P1 (1,2-dio...
T14553 BHPI Others
BHPI is a potent ERα inhibitor that blocks nuclear estrogen–ERα-regulated gene expression effectively. It triggers sustained ERα-dependent activation of the endoplasmic reticulum (EnR) stress sensor, notably the unfolded...
T36937 PtdIns-(1,2-dioctanoyl) (sodium salt)
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(1,2-dioctanoyl...
TargetMol