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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T30935 | Ci-IP3/PM | ||
CI-IP3 /PM is a cell-permeable caged inositol triphosphate that promotes the release of Ca2+ from internal storage under UV photolysis. | |||
T19266 | Ins(1,4,5)-P3 hexapotassium salt | 1,4,5-IP3 hexapotassium salt,D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt | Others |
D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt is promotes endoplasmic The second messenger of net calcium ions. | |||
T8867 | RO2959 Hydrochloride | RO2959 HCl | IL Receptor , Calcium Channel , Interleukin |
RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2. | |||
T41181 | iP300v | ||
iP300v is a negative control for iP300w | |||
T83733 | TIP39 (human, bovine) TFA | Tuberoinfundibular Peptide of 39 Residues | |
TIP39, a neuropeptide and an agonist for the parathyroid hormone receptor type 2 (PTH2R), effectively increases cAMP levels in COS-7 cells featuring recombinant PTH2R from humans or rats (EC50s = 0.5 and 0.8 nM, respecti... | |||
T68759 | OSIP339391 | ||
OSIP339391 is a A2BAR antagonist. | |||
T4693 | 2-Aminoethyl diphenylborinate | 2-Aminoethoxydiphenyl borate,2-APB | Calcium Channel , TRP/TRPV Channel |
2-Aminoethyl diphenylborinate (2-APB) is a chemical that acts to inhibit both IP3 receptors and TRP channels (although it activates TRPV1, TRPV2, & TRPV3 at higher concentrations). | |||
T11137 | (E)-GABAB receptor antagonist 1 | GABA Receptor | |
(E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM. GABAB receptor antagonist 1 is ... | |||
T9031 | MCU-i4 | Others , Mitochondrial Metabolism | |
MCU-i4 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth. | |||
T7190 | Actein | Apoptosis , Akt , JNK , Autophagy | |
Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein's ability to pathways in... | |||
T23538 | Xestospongin C | (-)-Xestospongin C | Others |
IP3-dependent Ca2+ release inhibitor | |||
TP1710 | Calmodulin Binding Peptide 1 | ||
Calmodulin Binding Peptide 1, a potent CaM-binding peptide with picomolar (pM) affinity, originates from smooth muscle myosin light-chain kinase (MLCK peptide). It effectively blocks inositol trisphosphate (IP3)-induced ... | |||
T14202 | AM-4668 | GPR | |
AM-4668 is a type 2 diabetes GPR40 agonist. For GPR40, in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), the EC50s are 3.6 nM and 36 nM, respectively. | |||
T83950 | ARN 11391 | ||
ARN 11391 enhances the function of the IP3-gated calcium channel ITPR1 (Inositol 1,4,5-trisphosphate (IP3) receptor type 1), boosting intracellular calcium ion signaling by directly targeting ITPR1. Furthermore, ARN 1139... | |||
T11350 | GABAB receptor antagonist 1 | GABA Receptor | |
(E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric ac... | |||
T37030 | PtdIns-(4)-P1 (1,2-dioctanoyl) (ammonium salt) | PtdIns-(4)-P1 (1,2-dioctanoyl) (ammonium salt) | |
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4)-P1 (1,2-dio... | |||
T14553 | BHPI | Others | |
BHPI is a potent ERα inhibitor that blocks nuclear estrogen–ERα-regulated gene expression effectively. It triggers sustained ERα-dependent activation of the endoplasmic reticulum (EnR) stress sensor, notably the unfolded... | |||
T36937 | PtdIns-(1,2-dioctanoyl) (sodium salt) | ||
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(1,2-dioctanoyl... |