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AM-4668

Catalog No. T14202 CAS 1011531-27-3

AM-4668 is a type 2 diabetes GPR40 agonist. For GPR40, in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), the EC50s are 3.6 nM and 36 nM, respectively.

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AM-4668, CAS 1011531-27-3

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	AM-4668 is a type 2 diabetes GPR40 agonist. For GPR40, in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), the EC50s are 3.6 nM and 36 nM, respectively.
Targets&IC50	GPR40:（EC50）3.6 nM, GPR40, in CHO cells:36 nM（EC50）

Molecular Weight	488.48
Formula	C24H19F3N2O4S
CAS No.	1011531-27-3

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Liu JJ, et al. Optimization of GPR40 Agonists for Type 2 Diabetes. ACS Med Chem Lett. 2014 Feb 6;5(5):517-21.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

AM-4668 1011531-27-3 G蛋白偶联受体内分泌与激素 GPR AM 4668 AM4668 Inhibitor inhibitor inhibit

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