Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM. GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
2 mg | In stock | $ 293.00 | |
5 mg | In stock | $ 447.00 | |
10 mg | In stock | $ 659.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,380.00 | |
100 mg | In stock | $ 1,890.00 | |
500 mg | In stock | $ 3,790.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 431.00 |
Description | (E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM. GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors. |
In vitro | (E)-GABAB receptor antagonist 1 reduces the maximum effect of IP3 in HEK293 cells overexpressing GABAB receptor and Gqi9 protein induced by agonist GABA, but does not alter EC50[1]. |
Molecular Weight | 304.38 |
Formula | C18H24O4 |
CAS No. | 1611483-29-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (164.27 mM)
You can also refer to dose conversion for different animals. More
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(E)-GABAB receptor antagonist 1 1611483-29-4 Membrane transporter/Ion channel Neuroscience GABA Receptor (E) GABAB receptor antagonist 1 (E)GABAB receptor antagonist 1 GABAB receptor antagonist 1 inhibitor inhibit