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Search Result

Search Results for " grp "

Targets

CGRP Receptor Others

48

Compounds

3

Natural Products

14

Recombinant Proteins

Cat No. Product Name Synonyms Targets
TP2026L GRP (porcine) acetate GRP (porcine) acetate(74815-57-9 Free base) Others
GRP (porcine) acetate is the gastrin-releasing peptide extracted from porcine pancreata. GRP (porcine) acetate may have a role in the parasympathetic regulation of endocrine and exocrine secretion from the pig pancreas.
T8701 GRP-60367 Others
GRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.
TP2026 GRP (porcine)
Mammalian bombesin-like peptide neurotransmitter that is an agonist for the gastrin-releasing peptide receptor (GRPR). GRP has been reported to activate GABAergic interneurons in the amygdala leading to increased GABA re...
T36864 GRP (human) (trifluoroacetate salt)
Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release. It binds to (Ki = 300 nM) and stimulates amylase secretion in rat pancreatic AR42J cells (EC50 = 0.3 nM). GRP increases proliferation of ...
T61763 GRP-60367 hydrochloride
GRP-60367 hydrochloride is a novel small-molecule entry inhibitor of rabies virus (RABV), exhibiting nanomolar potency against select RABV strains. This first-in-class compound effectively targets the RABV G protein [1].
T82162 Human follicular gonadotropin releasing peptide hF-GRP
Human Follicular Gonadotropin Releasing Peptide (hF-GRP) is a hormonal peptide that, in vitro, can induce the secretion of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) [1] [2].
T80148 GRP (14-27) (human, porcine, canine) Bombesin Receptor
GRP (14-27) (human, porcine, canine) functions as a ligand for bombesin receptors, with its specific binding being inhibited by GTP and GDP, while GMP does not affect it [1].
T7261 Grp94 Inhibitor-1 GPR , HSP
Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).
T13453 CGRP antagonist 1 CGRP Receptor
CGRP antagonist 1 is a potent CGRP receptor antagonist with Ki values of 35 nM and IC50 values of 57 nM, respectively.CGRP antagonist 1 can be used for the study of cardiovascular and neurovascular diseases.
TP2044L α-CGRP (human) acetate α-CGRP (human) acetate (90954-53-3 free base) Others
α-CGRP (human) acetate is a regulatory neuropeptide of 37 amino acids. It is the most potent vasodilator known to date and has inotropic and chronotropic effects.
TP1200 CGRP (83-119), rat TFA Calcitonin Gene Related Peptide(83-119), rat TFA Others
CGRP (83-119), rat TFA (Calcitonin Gene Related Peptide(83-119), rat TFA) is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor.
TP2233L CGRP (rat) acetate Others
CGRP (rat) acetate is a calcitonin gene-related peptide (CGRP). CGRP (rat) acetate is a potent vasodilator.
TP1323 CGRP 8-37 (rat) CGRP Receptor
CGRP 8-37 (rat) is a CGRP receptor antagonist, a CGRP fragment with potential anti-injury effects that induces arterial relaxation.
T67897 GRP78-IN-3 HSP
GRP78-IN-3, a potent small-molecule-competitive inhibitor of Hsp70 substrate binding and is a selective Grp78 (HSPA5) inhibitor with an IC50 of 0.59 μM. GRP78-IN-3 is 7-fold selective for HspA5 compared to HspA9 (IC50 of...
TP1134L HCGRP-(8-37) acetate HCGRP-(8-37) acetate (119911-68-1 free base) CGRP Receptor
HCGRP-(8-37) acetate is a human calcitonin gene-related peptide (hCGRP) fragment acetate and also an antagonist of CGRP receptor.
T75788 α-CGRP(human) TFA
α-CGRP(human) TFA is a 37-amino acid regulatory neuropeptide that is extensively located within the central and peripheral nervous system, functioning as a potent vasodilator [1].
TP1203 CGRP(83-119), rat Calcitonin Gene Related Peptide (CGRP) (83-119), rat
Calcitonin Gene Related Peptide (CGRP) (83-119), rat is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor.
T75978 β-CGRP, human TFA
Human β-CGRP TFA (β-CGRP, human TFA) is a calcitonin peptide that functions through interaction with the calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP) complex, demonstrating IC50...
TP2044 α-CGRP(human) α-CGRP (human)
Endogenous calcitonin gene-related peptide receptor (CGRP) agonist.
TP2215 Agouti-related Protein (AGRP) (25-82), human Others
Agouti-related peptide (AgRP) is a neuropeptide produced in the brain by the AgRP/NPY neuron. It is only synthesized in NPY containing cell bodies located in the ventromedial part of the arcuate nucleus in the hypothalam...
T76301 Agouti-related Protein (AGRP) (83-132) Amide (human)
Agouti-related Protein (AGRP) (83-132) Amide (human) is a segment derived from the agouti-related protein (AGRP), abundantly present in the hypothalamus' arcuate nucleus. It predominantly functions as an inverse agonist ...
T63952 GRPR antagonist-2
GRPR antagonist-2 is a potent antagonist of the gastrin-releasing peptide receptor (GRPR) and exhibits anticancer effects by being cytotoxic to certain cancer cells (able to act on HGC-27 cells (IC50: 0.77 μM) and Pan02 ...
T63243 GRP78-IN-2
GRP78-IN-2 is a glucose regulatory protein 78 (GRP78) inhibitor that preferentially targets GRP78 on the cell surface and has significant anti-angiogenic and anti-cancer effects without affecting other normal cells.
TP2233 α-CGRP, rat CGRP (rat) Others
Endogenous neuropeptide, potent vasodilator
T61106 GRP78-IN-1
GRP78-IN-1 displays interactions with specific residues on the GRP78 protein with a binding energy of -8.07 kcal/mol. This compound possesses potent cytotoxic and anti-proliferative effects on cancer cells, particularly ...
TP1202 Calcitonin Gene Related Peptide (CGRP) II, rat CGRP II, rat
Calcitonin Gene Related Peptide II is a potent, long-lasting vasodilator; activation of CGRP receptors on pancreatic β-cells increases plasma levels of pancreatic enzymes.
TP1134 HCGRP-(8-37) Human α-CGRP (8-37)
Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist
TP1130 β-CGRP, human CGRP-II (Human),Human β-CGRP
β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascular and nervous systems. β-CGRP contains a disulphide bridge at th...
T75732 α-CGRP, rat TFA
α-CGRP, rat TFA, a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP, rat TFA can lead to a fall in blood pressure and an increase in heart ...
T63947 GRPR antagonist-1
GRPR antagonist-1 is a potent antagonist of the gastrin-releasing peptide receptor (GRPR) and is cytotoxic to certain cancer cells (able to act on PC3 cells (IC50: 4.97 μM), Pan02 cells (IC50: 4.36 μM), HGC-27 cells (IC5...
T70088 Grp94-IN-2
Grp94-IN-2 is a inhibitor of Grp94.
T36555 Tyr-α-CGRP (human) (trifluoroacetate salt)
Tyr-α-CGRP is an N-terminal extended tyrosinated analogue of α-calcitonin gene-related peptide . It binds to amylin receptors AMY1 and AMY3 in COS-7 cells expressing the human receptors (IC50s = 141 and 1.86 nM, respecti...
TP1201 CGRP II, rat (TFA) (99889-63-1 free base) Calcitonin Gene Related Peptide (CGRP) II, rat (TFA),CGRP II, rat (TFA)
Calcitonin Gene Related Peptide (CGRP) II, rat (TFA) is a neuropeptide with 37 amino acid.
T76032 Calcitonin Gene Related Peptide (CGRP) II, rat TFA
Calcitonin Gene-Related Peptide (CGRP) II, rat TFA, functions as a potent and enduring vasodilator by activating CGRP receptors. This compound is utilized in cardiovascular disease research [1].
T80149 GRPP (human)
GRPP (human), a 30-amino-acid peptide derived from Gcg, modestly elevates plasma insulin levels while reducing plasma glucagon concentrations. However, GRPP (human) has no impact on insulin secretion within rat islets [1...
TP1131 β-CGRP, human TFA (101462-82-2 free base) CGRP-II (Human) (TFA),Human β-CGRP (TFA),β-CGRP, human TFA
β-CGRP,human tissue is one of the calcitonin peptide, through complex behavior of calcitonin receptor like receptor (CRLR) - and receptor activity - modifying proteins (increased), and 1 and 300 - nM CRLR IC50s/RAMP1 and...
T82079 IGRP(206-214)
IGRP(206-214) is an bioactive peptide corresponding to residues 206–214 of the murine islet-specific glucose-6-phosphatase catalytic subunit–related protein (IGRP). It induces diabetes in non-obese diabetic (NOD) mice by...
T78540 α-CGRP (mouse, rat) TFA CGRP Receptor
α-CGRP (mouse, rat) TFA, a neuropeptide belonging to the calcitonin gene-related peptide (CGRP) family, is predominantly located at neuromuscular junctions and functions as a potent vasodilator. Peripheral administration...
T38190 Tyr-α-CGRP (rat) (trifluoroacetate salt)
Tyr-α-CGRP (rat) is an N-terminally tyrosinated analog of the neuropeptide α-CGRP that induces a fall in resting tension of isolated opossum internal anal sphincter (IAS) with an EC50 value of 178 nM.
TP1325L Gastrin-Releasing Peptide, human(TFA) Others
Gastrin-Releasing Peptide, human(TFA) is a regulatory human peptide that elicits gastrin release and regulates gastric acid secretion and enteric motor function. The post-ganglionic fibers of the vagus nerve that innerva...
T82881 Biotin-Gastrin Releasing Peptide, human
Biotin-Gastrin Releasing Peptide, human, is a biotinylated derivative of gastrin-releasing peptide (GRP), a neuropeptide known for its growth-stimulatory and tumorigenic properties [1].
T75834 Antagonist G TFA
Antagonist G TFA is a potent antagonist of vasopressin, with additional, weaker antagonistic effects on GRP and Bradykinin. This compound also promotes AP-1 transcription and enhances cellular sensitivity to chemotherapy...
T75707 BIM-26226
BIM-26226, a gastrin-releasing peptide, serves as a potent and selective antagonist to the bombesin receptor, effectively inhibiting BN- or GRP-stimulated amylase release with IC50 values in the nanomolar range. It is ut...
T35669 Neuromedin C (trifluoroacetate salt)
Neuromedin C is a bombesin-like neuropeptide that stimulates uterine smooth muscle contraction and the release of gastrin , somatostatin, and amylase in rats. Neuromedin C is a truncated form of gastrin-releasing peptide...
T25522 Ici 216140 m216140,Ici216140,m 216140,Ici-216140,m-216140
ICI 216140 is a GRP/bombesin receptor 2 antagonist (IC50: 2 nM in vitro). At 2 mg/kg, it can decrease bombesin-stimulated pancreatic amylase secretion in rats. At 1 mM, it has been proved to attenuate bombesin-stimulated...
TP1325 Gastrin-Releasing Peptide, human
Gastrin-Releasing Peptide, human is a regulatory human peptide that elicits gastrin release and regulates gastric acid secretion and enteric motor function. The post-ganglionic fibers of the vagus nerve that innervate th...
TP1701 RC-3095 TFA RC-3095 (TFA) Bombesin Receptor
RC-3095 TFA (RC-3095 (TFA)) is a bombesin/gastrin-releasing peptide (BN/GRP) antagonist with potential anticancer activity.
TP1054 PACAP (1-38), human, ovine, rat TFA Pituitary Adenylate Cyclase Activating Polypeptide 38 (TFA)
PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP...

Compounds

GRP (porcine) acetate
TP2026L
Synonym: GRP (porcine) acetate(74815-57-9 Free base)
Target: Others
GRP-60367
T8701
Synonym:
Target: Others
GRP (porcine)
TP2026
Synonym:
Target:
GRP (human) (trifluoroacetate salt)
T36864
Synonym:
Target:
GRP-60367 hydrochloride
T61763
Synonym:
Target:
Human follicular gonadotropin releasing peptide
T82162
Synonym: hF-GRP
Target:
GRP (14-27) (human, porcine, canine)
T80148
Synonym:
Target: Bombesin Receptor
Grp94 Inhibitor-1
T7261
Synonym:
Target: GPR, HSP
CGRP antagonist 1
T13453
Synonym:
Target: CGRP Receptor
α-CGRP (human) acetate
TP2044L
Synonym: α-CGRP (human) acetate (90954-53-3 free base)
Target: Others
CGRP (83-119), rat TFA
TP1200
Synonym: Calcitonin Gene Related Peptide(83-119), rat TFA
Target: Others
CGRP (rat) acetate
TP2233L
Synonym:
Target: Others
CGRP 8-37 (rat)
TP1323
Synonym:
Target: CGRP Receptor
GRP78-IN-3
T67897
Synonym:
Target: HSP
HCGRP-(8-37) acetate
TP1134L
Synonym: HCGRP-(8-37) acetate (119911-68-1 free base)
Target: CGRP Receptor
α-CGRP(human) TFA
T75788
Synonym:
Target:
CGRP(83-119), rat
TP1203
Synonym: Calcitonin Gene Related Peptide (CGRP) (83-119), rat
Target:
β-CGRP, human TFA
T75978
Synonym:
Target:
α-CGRP(human)
TP2044
Synonym: α-CGRP (human)
Target:
Agouti-related Protein (AGRP) (25-82), human
TP2215
Synonym:
Target: Others
Agouti-related Protein (AGRP) (83-132) Amide (human)
T76301
Synonym:
Target:
GRPR antagonist-2
T63952
Synonym:
Target:
GRP78-IN-2
T63243
Synonym:
Target:
α-CGRP, rat
TP2233
Synonym: CGRP (rat)
Target: Others
GRP78-IN-1
T61106
Synonym:
Target:
Calcitonin Gene Related Peptide (CGRP) II, rat
TP1202
Synonym: CGRP II, rat
Target:
HCGRP-(8-37)
TP1134
Synonym: Human α-CGRP (8-37)
Target:
β-CGRP, human
TP1130
Synonym: CGRP-II (Human),Human β-CGRP
Target:
α-CGRP, rat TFA
T75732
Synonym:
Target:
GRPR antagonist-1
T63947
Synonym:
Target:
Grp94-IN-2
T70088
Synonym:
Target:
Tyr-α-CGRP (human) (trifluoroacetate salt)
T36555
Synonym:
Target:
CGRP II, rat (TFA) (99889-63-1 free base)
TP1201
Synonym: Calcitonin Gene Related Peptide (CGRP) II, rat (TFA),CGRP II, rat (TFA)
Target:
Calcitonin Gene Related Peptide (CGRP) II, rat TFA
T76032
Synonym:
Target:
GRPP (human)
T80149
Synonym:
Target:
β-CGRP, human TFA (101462-82-2 free base)
TP1131
Synonym: CGRP-II (Human) (TFA),Human β-CGRP (TFA),β-CGRP, human TFA
Target:
IGRP(206-214)
T82079
Synonym:
Target:
α-CGRP (mouse, rat) TFA
T78540
Synonym:
Target: CGRP Receptor
Tyr-α-CGRP (rat) (trifluoroacetate salt)
T38190
Synonym:
Target:
Gastrin-Releasing Peptide, human(TFA)
TP1325L
Synonym:
Target: Others
Biotin-Gastrin Releasing Peptide, human
T82881
Synonym:
Target:
Antagonist G TFA
T75834
Synonym:
Target:
BIM-26226
T75707
Synonym:
Target:
Neuromedin C (trifluoroacetate salt)
T35669
Synonym:
Target:
Ici 216140
T25522
Synonym: m216140,Ici216140,m 216140,Ici-216140,m-216140
Target:
Gastrin-Releasing Peptide, human
TP1325
Synonym:
Target:
RC-3095 TFA
TP1701
Synonym: RC-3095 (TFA)
Target: Bombesin Receptor
PACAP (1-38), human, ovine, rat TFA
TP1054
Synonym: Pituitary Adenylate Cyclase Activating Polypeptide 38 (TFA)
Target:
Cat No. Product Name Synonyms Targets
TP2167 β-CGRP, human acetate β-CGRP, human acetate (101462-82-2 free),CGRP-II (Human) (acetate),Human β-CGRP acetate CGRP Receptor
β-CGRP, human acetate is one of calcitonin peptides and acts via the complex of receptor-activity-modifying protein (RAMP) and calcitonin-receptor-like receptor (CRLR) (IC50s: 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP...
TN1849 Kuwanon H GPR , Bombesin Receptor
Kuwanon H, and possibly kuwanon G also, are specific antagonists for the gastrin-releasing peptide (GRP) -preferring receptor and can be useful for studying the physiological and pathological role of GRP.
T3S1612 Kuwanon G Moracenin B,Kuwanone G Phosphatase , Antibacterial , Bombesin Receptor , AChR , AChE , Glucosidase
1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. 2. Kuwanon G has a...

Natural Products

β-CGRP, human acetate
TP2167
Synonym: β-CGRP, human acetate (101462-82-2 free),CGRP-II (Human) (acetate),Human β-CGRP acetate
Target: CGRP Receptor
Kuwanon H
TN1849
Synonym:
Target: GPR, Bombesin Receptor
kuwanon G
T3S1612
Synonym: Moracenin B,Kuwanone G
Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase

Recombinant Proteins

Species：
Human (7)
Mouse (3)
Bovine (1)
Canine (1)
Fruit fly (1)
Rhesus (1)
Expression System：
HEK293 Cells (8)
E. coli (6)
Tag：
C-hFc (3)
His (3)
N-10xHis, C-Myc (2)
Tag Free (2)
C-6xHis (1)
N-6xHis (1)
N-hFc (1)
N-mFc (1)
Cat No. Product Name Species Expression System
TMPK-01370 GRP-10 proform Protein, Canine, Recombinant (hFc) Canine HEK293 Cells
Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties, and neuropeptides have previously been suggested to play a role in the complex cascade of chemical activity associated...
TMPY-01577 ORP150 Protein, Human, Recombinant (His) Human HEK293 Cells
Hypoxia up-regulated protein 1, also known as 15 kDa oxygen-regulated protein, 17 kDa glucose-regulated protein, ORP-15, GRP-17, and HYOU1, is a member of the heat shock protein 7 family. Seven members from four differen...
TMPJ-01146 LGALSL Protein, Human, Recombinant (His) Human E. coli
Galectin-Related Protein (LGALSL) is a 172 amino acid protein that contains one Galectin domain. LGALSL does not appear to bind carbohydrates or lactose as the critical residues required for binding are not conserved. LG...
TMPJ-01410 LSM4 Protein, Human, Recombinant (His) Human E. coli
U6 snRNA-associated Sm-like protein LSm4 (LSM4) is a member of the snRNP Sm proteins family. Sm-like proteins contain the Sm sequence motif and are thought to form a stable heteromer present in tri-snRNP particles, which...
TMPY-03655 GADD45G Protein, Human, Recombinant Human E. coli
GADD45G, also known as CR6, is part of the nuclear proteins to interact with various proteins whose transcript levels are raised after stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G re...
TMPY-01369 AGRP Protein, Human, Recombinant (His) Human HEK293 Cells
AGRP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is C6SUN5.
TMPK-00678 CALCA/CGRP Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Specific fragments of methylation changes in the target gene (Calca) were identified by IGV analysis. CGRP was applied to compare the effects on ASCs-T2DM morphology via phalloidin staining, proliferation through CCK-8 a...
TMPY-00434 AGRP Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
AGRP Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.1 kDa and the accession number is P56473.
TMPY-02269 AGRP Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
AGRP Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.7 kDa and the accession number is P56473.
TMPH-00292 PGLYRP1/PGRP-S Protein, Bovine, Recombinant (His & Myc) Bovine E. coli
PGLYRP1/PGRP-S Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 26.3 kDa and the accession number is Q8SPP7.
TMPH-00507 PGRP-SC2 Protein, Drosophila melanogaster, Recombinant (His & Myc) Fruit fly E. coli
N-acetylmuramyl-L-alanine amidase involved in innate immunity by degrading bacterial peptidoglycans (PGN). Probably plays a scavenger role by digesting biologically active PGN into biologically inactive fragments. Has no...
TMPY-00630 AGRP Protein, Rhesus, Recombinant (mFc) Rhesus HEK293 Cells
AGRP Protein, Rhesus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 32.3 kDa and the accession number is A0A8J8XRM3.
TMPJ-01283 UGRP1 Protein, Human, Recombinant Human E. coli
Uteroglobin-Related Protein 1 (UGRP1) belongs to the secretoglobin family which has been suggested to play a role in lung inflammation and allergic diseases. UGRP1 is a 17 kDa secreted homodimeric protein that shows amin...
TMPY-00661 AGRP Protein, Human, Recombinant (hFc) Human HEK293 Cells
AGRP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39 kDa and the accession number is C6SUN5.
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