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GRP (porcine)

Catalog No. TP2026 CAS 74815-57-9

Mammalian bombesin-like peptide neurotransmitter that is an agonist for the gastrin-releasing peptide receptor (GRPR). GRP has been reported to activate GABAergic interneurons in the amygdala leading to increased GABA release and fear suppression in mice in vivo. Also involved in mitogenesis, and GI tract and appetite regulation.

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GRP (porcine), CAS 74815-57-9

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1 mg	Inquiry	$ 252.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	2805.31
Formula	C126H198N38O31S2
CAS No.	74815-57-9

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 1 mg/mL

References and Literature

1. Dudai (2003) Neurobiology: Fear thou not. Nature 421 325 PMID: 2. Schjoldager et al (1991) Gastrin-releasing peptide is a transmitter mediating porcine gallbladder contraction. Am.J.Physiol. 260 G577 PMID: 3. Shumyatsky et al (2002) Identification of a signaling network in lateral nucleus of amygdala important for inhibiting memory specifically related to learned fear. Cell 111 905 PMID: 4. Woodruff et al (1996) Bombesin receptors in the brain. Ann.N.Y.Acad.Sci. 780 223 PMID:

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Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

GRP (porcine) 74815-57-9 GRP porcine inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.