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Search Results for " fluorouracil "

20

Compounds

Cat No. Product Name Synonyms Targets
T0984 5-Fluorouracil 5-FU,Fluorouracil,NSC 19893,5-Fluoracil Apoptosis , Nucleoside Antimetabolite/Analog , HIV Protease , DNA/RNA Synthesis , Endogenous Metabolite
5-Fluorouracil (5-FU) is a uracil analog, an inhibitor of DNA synthesis. 5-Fluorouracil has antitumor activity and affects pyrimidine synthesis through inhibition of thymidylate synthase. 5-Fluorouracil causes apoptosis ...
T36895 5-Fluorouracil-13C,15N2 5-Fluorouracil-13C,15N2
5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking...
T36870 5,6-dihydro-5-Fluorouracil 5-fluorodihydrouracil,5-Fluoro-dihydro-pyrimidine-2,4-dione Others
5,6-dihydro-5-Fluorouracil (5-FUH2) is an inactive metabolite of 5-FU and can be used for the study of organismal metabolism.
T0964 Floxuridine 5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640 Apoptosis , Nucleoside Antimetabolite/Analog , Others , DNA/RNA Synthesis , Antibacterial , HSV
Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.
T10013 1-Acetyl-3-o-toluyl-5-fluorouracil A-​OT-​Fu Others
1-Acetyl-3-o-toluyl-5-fluorouracil is a potent antineoplastic agent.
TNU1053 5-Fluorouracil-1-yl  acetic acid
5-Fluorouracil-1-yl acetic acid is a PNA-related Derivative.
TNU1481 1-(b-D-Xylofuranosyl)-5-fluorouracil
1-(b-D-Xylofuranosyl)-5-fluorouracil is a Nucleoside Derivative - Xylo-nucleoside, Fluoro-modified nucleoside, 5-Modified pyrimidine nucleoside.
TNU1052 5-Fluorouracil-1-yl  acetic acid methyl ester
5-Fluorouracil-1-yl acetic acid methyl ester is a PNA-related Derivative.
T7614 Eniluracil GW776C85,5-Ethynyluracil Others
Eniluracil (GW776C85) is an orally activedihydropyrimidine dehydrogenase (DPD) inhibitor,increases the oral bioavailability of 5-FU to 100%, facilitating uniform absorption and predictable toxicity.
T1307 Carmofur HCFU Nucleoside Antimetabolite/Analog , Virus Protease , SARS-CoV , DNA/RNA Synthesis
Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.
T6431 Levoleucovorin Calcium Calcium Levofolinate,CL307782 Others , Antifolate
Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.
T33762 Fosifloxuridine nafalbenamide NUC-3373,NUC3373,NUC 3373 DNA/RNA Synthesis
Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor. NUC-3373 has anticancer activity. NUC-3373 is a ProTide transformation of 5-FU that generates much higher c...
T1378 Tegafur Fluorafur,FT-207,NSC 148958,FT 207 Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
Tegafur (FT 207) is a congener of the antimetabolite fluorouracil with antineoplastic activity. Tegafur is a prodrug that is gradually converted to fluorouracil in the liver by the cytochrome P-450 enzyme.
T1349 5-Fluorouridine Others , DNA/RNA Synthesis
5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compound...
T27342L Flurocitabine HCl Flurocitabine HCl(37717-21-8 Free base) Others
Flurocitabine HCl is a fluorinated anhydride analog of cytarabine, which is partially hydrolyzed in vivo to two active antitumor substances (arabinosyl-fluorouracil (ara-FC) and arabinosyl-fluorouracil (ara-FU)).Flurocit...
T27259 Emitefur BOFA2,BOF A2,BOF-A2 Others
Emitefur (BOF-A 2) is an orally active and potent 5-fluorouracil derivative with anticancer and antitumor activity.Emitefur is used in advanced gastric cancer, breast cancer and metabolism-related diseases.
T4720 6-Hydroxypyridin-2(1H)-one hydrochloride 2,6-Dihydroxypyridine hydrochloride Others , Endogenous Metabolite
6-Hydroxypyridin-2(1H)-one hydrochloride (2,6-Dihydroxypyridine hydrochloride) is used as a reagent to synthesize uridine phosphorylase inhibitors that increase Uridine (Urd) (U829910) levels. Uridine is a promising bioc...
T9936 ZX-J-19J N-(2,3-Diphenyl-6-quinoxalinyl)octanamide Others
ZX-J-19J (N-(2,3-Diphenyl-6-quinoxalinyl)octanamide), an inhibitor of Cyclophilin J (CyPJ), demonstrates remarkable inhibition of tumor cell growth, comparable to cyclosporine A but much stronger than 5-fluorouracil.
T1408 Capecitabine Xeloda,Capecitibine,Capiibine,RO 09-1978 Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
Capecitabine (Capecitibine) is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moie...
T1600 Doxifluridine Ro 21-9738,AMC 0101,5'-DFUR,5-Fluoro-5'-deoxyuridine Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designed to circumvent the rapid degradation of 5-FU by...

Compounds

5-Fluorouracil
T0984
Synonym: 5-FU,Fluorouracil,NSC 19893,5-Fluoracil
Target: Apoptosis, Nucleoside Antimetabolite/Analog, HIV Protease, DNA/RNA Synthesis, Endogenous Metabolite
5-Fluorouracil-13C,15N2
T36895
Synonym: 5-Fluorouracil-13C,15N2
Target:
5,6-dihydro-5-Fluorouracil
T36870
Synonym: 5-fluorodihydrouracil,5-Fluoro-dihydro-pyrimidine-2,4-dione
Target: Others
Floxuridine
T0964
Synonym: 5-Fluorouracil 2'-deoxyriboside,FUDR,Deoxyfluorouridine,NSC 27640
Target: Apoptosis, Nucleoside Antimetabolite/Analog, Others, DNA/RNA Synthesis, Antibacterial, HSV
1-Acetyl-3-o-toluyl-5-fluorouracil
T10013
Synonym: A-​OT-​Fu
Target: Others
5-Fluorouracil-1-yl  acetic acid
TNU1053
Synonym:
Target:
1-(b-D-Xylofuranosyl)-5-fluorouracil
TNU1481
Synonym:
Target:
5-Fluorouracil-1-yl  acetic acid methyl ester
TNU1052
Synonym:
Target:
Eniluracil
T7614
Synonym: GW776C85,5-Ethynyluracil
Target: Others
Carmofur
T1307
Synonym: HCFU
Target: Nucleoside Antimetabolite/Analog, Virus Protease, SARS-CoV, DNA/RNA Synthesis
Levoleucovorin Calcium
T6431
Synonym: Calcium Levofolinate,CL307782
Target: Others, Antifolate
Fosifloxuridine nafalbenamide
T33762
Synonym: NUC-3373,NUC3373,NUC 3373
Target: DNA/RNA Synthesis
Tegafur
T1378
Synonym: Fluorafur,FT-207,NSC 148958,FT 207
Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis
5-Fluorouridine
T1349
Synonym:
Target: Others, DNA/RNA Synthesis
Flurocitabine HCl
T27342L
Synonym: Flurocitabine HCl(37717-21-8 Free base)
Target: Others
Emitefur
T27259
Synonym: BOFA2,BOF A2,BOF-A2
Target: Others
6-Hydroxypyridin-2(1H)-one hydrochloride
T4720
Synonym: 2,6-Dihydroxypyridine hydrochloride
Target: Others, Endogenous Metabolite
ZX-J-19J
T9936
Synonym: N-(2,3-Diphenyl-6-quinoxalinyl)octanamide
Target: Others
Capecitabine
T1408
Synonym: Xeloda,Capecitibine,Capiibine,RO 09-1978
Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis
Doxifluridine
T1600
Synonym: Ro 21-9738,AMC 0101,5'-DFUR,5-Fluoro-5'-deoxyuridine
Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis
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TargetMol