Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of 5-fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase, or through incorporation into RNA and DNA, ultimately initiating apoptosis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 838.00 |
Description | 5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of 5-fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase, or through incorporation into RNA and DNA, ultimately initiating apoptosis. |
Synonyms | 5-Fluorouracil-13C,15N2 |
Molecular Weight | 133.057 |
Formula | C4H3FN2O2 |
CAS No. | 1189423-58-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Slightly soluble
Methanol: Slightly soluble
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5-Fluorouracil-13C,15N2 1189423-58-2 5-Fluorouracil-13C,15N-2 5Fluorouracil13C,15N2 5 Fluorouracil 13C,15N2 inhibitor inhibit