fda — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2S0850	Malic acid	E 296,2-Hydroxysuccinic acid,Hydroxybutanedioic acid,FDA 2018,Deoxytetraric acid,Pomalus acid	Others , Endogenous Metabolite
	1. Malic acid (Pomalus acid) did reduce populations of L. monocytogenes on poultry. 2. Malic acid supplementation may be useful for conservative treatment of calcium renal stone disease by virtue of its capacity to induc...		Others , Endogenous Metabolite
T33276	Mefruside	FDA1902,FDA-1902,FDA 1902,FBA-1500,FBA1500,FBA 1500
	Mefruside is a diuretic indicated for the treatment of edema and hypertension.
T30990	CMFDA	5-Chloromethylfluorescein diacetate,Cell Tracker Green,CM-FDA,CM FDA
	CMFDA can be used as a fluorescent whole-cell-tracking reagent.
T0459	Sulindac	Arthrocine,MK-231,Clinoril,Sulindac sulfoxide	COX , Autophagy
	Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cycl...		COX , Autophagy
T18894	5(6)-CFDA	CFDA,5-(6)-Carboxyfluorescein diacetate	Others
	5(6)-CFDA (5-(6)-Carboxyfluorescein diacetate) is a cell-permeant esterase substrate that can serve as a viability probe that measures both enzymatic activities, which is required to activate its fluorescence, and cell-m...		Others
T14057	6-CFDA	6-Carboxyfluorescein diacetate	Others
	6-CFDA (6-Carboxyfluorescein diacetate) is fluorescent polyanionic probe that used to measure changes in intracellular pH (pHi) and processes such as dendrimer aggregation and absorption.		Others
T14048	5-CFDA	5-Carboxyfluorescein diacetate	Others
	5-CFDA (5-Carboxyfluorescein diacetate)(5-Carboxyfluorescein diacetate) is membrane-permeant. It can be loaded into cells via incubation and hydrolyzed by intracellular esterases to 5-carboxyfluorescein that is used for ...		Others
T4433	6-CFDA N-succinimidyl ester	Carboxyfluorescein diacetate succinimidyl	Others
	6-CFDA N-succinimidyl ester (Carboxyfluorescein diacetate succinimidyl) is capable of spontaneously and irreversibly binding to free amines. Utilized in flow cytometry experiments for tracking cell division in both mamma...		Others
T15458	H2DCFDA	2',7'-Dichlorodihydrofluorescein diacetate,DCFH-DA	Reactive Oxygen Species
	H2DCFDA (DCFH-DA) belongs to the class of green fluorescent dyes and is a probe for the detection of intracellular reactive oxygen species (ROS) (Ex/Em=488/525 nm) with cell membrane permeability.		Reactive Oxygen Species
T35649	EFdA-TP tetraammonium
	EFdA-TP tetraammonium is an influential nucleoside reverse transcriptase (RT) inhibitor that effectively prevents RT-mediated DNA synthesis by acting as an immediate or delayed chain terminator (ICT or DCT). Additionally...
T41110	EFdA-TP
	EFdA-TP, a highly potent nucleoside reverse transcriptase (RT) inhibitor, exerts its inhibitory effect on RT-catalyzed DNA synthesis through both immediate and delayed chain termination mechanisms, commonly referred to a...
T72461	EFdA-TP tetrasodium		Reverse Transcriptase
	EFdA-TP tetrasodium, a potent nucleoside reverse transcriptase (RT) inhibitor, effectively halts RT-catalyzed DNA synthesis by acting as an immediate or delayed chain terminator (ICT or DCT). It employs multiple mechanis...		Reverse Transcriptase
T30991	CM-H2DCFDA	CMH2DCFDA,CM H2DCFDA
	CM-H2DCFDA is a fluorescent indicator for reactive oxygen species (ROS) in cells.
T83293	5-CFDA-AM
	5-CFDA-AM is a cell-permeable esterase substrate employed as an active probe to assess enzyme activity and cell membrane integrity. Electroneutral and capable of entering cells at concentrations lower than CFDA, it under...
T5149	MC-Val-Cit-PAB		Others , AChR
	MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.		Others , AChR
T67694	ZY-19489		Parasite
	ZY-19489 is an antimalarial compound that is a potential single-dose cure for Plasmodium falciparum and Plasmodium vivax malaria. It has received orphan drug designation from the FDA.		Parasite
T0845	Cyromazine	CGA-72662,Cyromazin	Others , Endogenous Metabolite
	Cyromazine (CGA-72662) is an ectoparasiticide. Insect growth regulator. Specific activity against dipterous larvae. Cyromazine is a fda approved for use in livestock.		Others , Endogenous Metabolite
T6620	Ospemifene	FC-1271a	Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Ospemifene (FC-1271a) is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. FDA ap...		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T7527	Frentizole		Beta Amyloid
	Frentizole, an immunosuppressive agent, is an inhibitor of the Aβ-ABAD interaction		Beta Amyloid
T0179	Ticagrelor	AR-C 126532XX,AZD6140	P450 , P2Y Receptor
	Ticagrelor (AR-C 126532XX), produced by AstraZeneca, is an inhibitor of platelet aggregation. Unlike clopidogrel, ticagrelor is not a prodrug required metabolic activation. The drug was approved for use in the European U...		P450 , P2Y Receptor