Search Result

Search Results for " dpp4 "

Targets

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T23358	Sitagliptin phosphate	Januvia,MK-0431 phosphate,Sitagliptin (phosphate)	DPP-4 , Autophagy
	Sitagliptin phosphate (MK-0431 phosphate) is a dipeptidyl peptidase-4 (DPP4) inhibitor.		DPP-4 , Autophagy
T0178	Saxagliptin hydrate	Onglyza hydrate,BMS-477118 hydrate	Proteasome , DPP-4
	Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).		Proteasome , DPP-4
T6203	Saxagliptin	BMS-477118,Onglyza	Proteasome , DPP-4
	Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.		Proteasome , DPP-4
T2316	Omarigliptin	MK-3102	Proteasome , DPP-4
	Omarigliptin (MK-3102) has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Chronic Renal Insufficiency.		Proteasome , DPP-4
T4042	Talabostat mesylate	Val-boroPro,PT100	Proteasome , DPP-4
	Talabostat mesylate (PT100) is an orally active, selective inhibitor of dipeptidyl peptidases IV (DPP4, IC50: 0.18 nM), including tumor-associated fibroblast activation protein. This agent may also stimulate the producti...		Proteasome , DPP-4
T15079	DBPR108		Proteasome , DPP-4
	DBPR108 is an orally bioavailable dipeptide-derived DPP4 inhibitor (IC50: 15 nM) and it has no inhibition on DDP8 and DPP9.		Proteasome , DPP-4
T50018	1-(3-chloropyridin-2-yl)piperazine dihydrochloride		Others
	1-(3-chloropyridin-2-yl)piperazine dihydrochloride is a piperazine analog often used as a reagent in organic synthesis, as a ligand in coordination chemistry, and as a drug in pharmaceuticals. It is an inhibitor of DPP4,...		Others
T21979	P32/98 hemifumarate	P32/98 (hemifumarate)(136259-20-6 free base)	DPP-4
	P32/98 hemifumarate is a dipeptidyl peptidase IV (DPP4) inhibitor with hypoglycemic properties that improves insulin sensitivity and β-cell responsiveness in the Zucker diabetic rat model, and may be useful in studies of...		DPP-4
T0242	Sitagliptin	MK0431	Proteasome , DPP-4 , Autophagy
	Sitagliptin (MK0431), a new oral hypoglycemic (anti-diabetic drug), is a new dipeptidyl peptidase-4 (DPP-4) inhibitor. This enzyme-inhibiting drug is used either alone or in combination with metformin or thiazolidinedion...		Proteasome , DPP-4 , Autophagy
T2296	Trelagliptin succinate	SYR-472 succinate,SYR472	Proteasome , DPP-4
	Trelagliptin succinate (SYR-472 succinate) is a long-acting inhibitor of dipeptidyl peptidase-4 (DPP-4), being developed for the treatment of type 2 diabetes (T2D).		Proteasome , DPP-4
T0191	Linagliptin	BI 1356	Ferroptosis , Proteasome , DPP-4 , Autophagy
	Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.		Ferroptosis , Proteasome , DPP-4 , Autophagy
T8550	NDMC101		Others , NF-κB , Proteasome
	NDMC101 is an inhibitor of dipeptidyl peptidase-IV activity in human T cells and exhibits immunomodulatory effects. It also acts as a novel inhibitor of NFATc1 and NF-κB activity.		Others , NF-κB , Proteasome
T67852	Linagliptin Methyldimer		Proteasome
	Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.		Proteasome
T2401	Alogliptin Benzoate	SYR 322,Alogliptin(SYR-322)benzoate	Ferroptosis , Proteasome , DPP-4
	Alogliptin Benzoate (SYR 322)(SYR 322), an effective and specific DPP-4 inhibitor (IC50<10 nM), exhibits greater than 10, 000-fold selectivity over DPP-8/9. Alogliptin may inhibit inflammatory responses by preventing the...		Ferroptosis , Proteasome , DPP-4
T78223	γ-Glu-Tyr	gamma-Glutamyltyrosine,gamma-GLU-TYR
	γ-Glu-Tyr (gamma-Glutamyltyrosine) is a kokumi peptide with competitive inhibition of dipeptidyl peptidase-IV (DPP-IV) and is used in the study of diabetes mellitus.
T0242L	Sitagliptin phosphate monohydrate	MK-0431,MK-0431 phosphate monohydrate	Proteasome , DPP-4 , Autophagy
	Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.		Proteasome , DPP-4 , Autophagy
T6192	Alogliptin	SYR-322	Ferroptosis , Proteasome , DPP-4
	Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9.		Ferroptosis , Proteasome , DPP-4
T1502	Vildagliptin	NVP-LAF 237,LAF237	Apoptosis , Ferroptosis , Proteasome , DPP-4
	Vildagliptin (LAF237) is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin's cyano moiety undergoes hydrolysis and this inactive metabolit...		Apoptosis , Ferroptosis , Proteasome , DPP-4
T6999	Teneligliptin hydrobromide	Teneligliptin hydrobromide anhydrous,MP-513 (hydrobromide)	Others , Proteasome , DPP-4
	Teneligliptin hydrobromide (MP-513 (hydrobromide)) is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50 ...		Others , Proteasome , DPP-4
T7369	Gemigliptin	LC15-0444	Proteasome , DPP-4
	Gemigliptin (LC15-0444) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)		Proteasome , DPP-4
T6237	Trelagliptin	SYR-472	Proteasome , DPP-4
	Trelagliptin (SYR-472) is a highly specific and long-acting DPP-4 inhibitor.		Proteasome , DPP-4
T7369L	Gemigliptin Tartrate(911637-19-9 free base)	LC15-0444 tartrate	Proteasome , DPP-4
	Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibit...		Proteasome , DPP-4
T7133	Anagliptin	SK-0403	Proteasome , DPP-4
	Anagliptin (SK-0403) is a potent Inhibitor of DPP-4(IC50 of 3.8 nM), for the treatment of type 2 diabetes mellitus.		Proteasome , DPP-4
T79256	DPP-4-IN-8
	DPP-4-IN-8 (compound 27) is a potent and selective inhibitor of dipeptidyl peptidase 4 (DPP4), with an inhibition constant (Ki) of 0.96 μM. It inhibits the dipeptidase activity of DPP4 in both Caco-2 and HepG-2 cells and...
T6203L	Saxagliptin hydrochloride	BMS477118,Saxagliptin,BMS 477118,Saxagliptin HCl,BMS-477118
	Saxagliptin is a new oral hypoglycemic of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones and reducing fas...
T11127	Dutogliptin tartrate	PHX-1149	Others
	Dutogliptin tartrate is an effective and selective oral dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.		Others
T11128	Dutogliptin	PHX-1149 free base	Others
	Dutogliptin (PHX-1149 free base) is an oral, effective and selective dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.		Others
T40930	(S)-Sitagliptin phosphate	(S)-Sitagliptin phosphate,(S)-MK-0431 phosphate
	(S)-Sitagliptin phosphate, the less active S-enantiomer of Sitagliptin phosphate, is a high-potency inhibitor of DPP4. It exhibits an IC50 of 19 nM in Caco-2 cell extracts.
T31732	Evogliptin HCl	Evogliptin hydrochloride,DA 1229,DA1229,Evogliptin,DA-1229
	Evogliptin(DA-1229) is a potent and selective DPP4 inhibitor (dipeptidyl peptidase 4 inhibitor) that can improve insulin resistance and delays the onset of diabetes. Evogliptin delays the onset of diabetes in young db/db...
T36652	Anti-MERS-3A1 mAb	Anti-MERS-3A1 mAb
	Anti-MERS-3A1 mAb (MERS-3A1) is a high-affinity human monoclonal IgG1 antibody derived from CHO cells. It effectively inhibits the interaction between the MERS-CoV spike protein and the DPP4 receptor[1].
T36445	Neuropeptide Y (3-36) (human, rat)
	Neuropeptide Y (3-36) (human, rat) is a metabolite of neuropeptide Y (NPY) generated by dipeptidyl peptidase-4 (DPP4). Known as a selective Y2 receptor agonist, Neuropeptide Y (3-36) (human, rat) effectively reduces the ...
T76669	Anti-MERS-D12 mAb
	Anti-MERS-D12 mAb (MERS-D12; MERS Antibody-D12), a human monoclonal IgG1, specifically targets the DPP4 interacting region of the MERS-CoV Spike receptor binding domain (RBD). By directly binding to this region, it effec...
T61949	Evogliptin
	Evogliptin (DA-1229) is a DPP4 inhibitor with oral activity. Evogliptin has significant and lasting hypoglycemic effect in mouse model. Evogliptin inhibits the production of the fibrosis and inflammatory in hepatocytes s...
T39481	NVP-DPP728 dihydrochloride	NVP-DPP728 dihydrochloride
	NVP-DPP728 dihydrochloride is a highly potent, selective, and orally active inhibitor of dipeptidyl peptidase IV (DPP-IV), with a binding affinity (K i ) of 11 nM. This compound proves useful for investigating diabetes m...
T13826	Prodipine hydrochloride		Others
	Prodipine hydrochloride for purified and plasma Dipeptidyl peptidase IV (DPP IV) from the rabbit (IC50 of 4.5 μM and 30 μM, respectively).		Others
T37522	Teneligliptin
	Teneligliptin (MP-513) is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM. Teneli...
T11864	Iptacopan	LNP023	Others
	Iptacopan (LNP023) is an inhibitor with high affinity for factor B.		Others
T37861	Talabostat
	Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM. Talabostat is a nonselective DPP-IV inhibitor, inhibiting DPP8/9, FAP, DPP2 ...

Compounds

Sitagliptin phosphate

T23358

Synonym: Januvia,MK-0431 phosphate,Sitagliptin (phosphate)

Target: DPP-4, Autophagy

Saxagliptin hydrate

T0178

Synonym: Onglyza hydrate,BMS-477118 hydrate

Target: Proteasome, DPP-4

Saxagliptin

T6203

Synonym: BMS-477118,Onglyza

Target: Proteasome, DPP-4

Omarigliptin

T2316

Synonym: MK-3102

Target: Proteasome, DPP-4

Talabostat mesylate

T4042

Synonym: Val-boroPro,PT100

Target: Proteasome, DPP-4

DBPR108

T15079

Synonym:

Target: Proteasome, DPP-4

1-(3-chloropyridin-2-yl)piperazine dihydrochloride

Synonym: P32/98 (hemifumarate)(136259-20-6 free base)

Target: Proteasome, DPP-4, Autophagy

Trelagliptin succinate

T2296

Synonym: SYR-472 succinate,SYR472

Target: Proteasome, DPP-4

Linagliptin

T0191

Synonym: BI 1356

Target: Ferroptosis, Proteasome, DPP-4, Autophagy

NDMC101

T8550

Synonym:

Target: Others, NF-κB, Proteasome

Linagliptin Methyldimer

Synonym: SYR 322,Alogliptin(SYR-322)benzoate

Target: Ferroptosis, Proteasome, DPP-4

γ-Glu-Tyr

T78223

Synonym: gamma-Glutamyltyrosine,gamma-GLU-TYR

Target:

Sitagliptin phosphate monohydrate

T0242L

Synonym: MK-0431,MK-0431 phosphate monohydrate

Target: Proteasome, DPP-4, Autophagy

Alogliptin

T6192

Synonym: SYR-322

Target: Ferroptosis, Proteasome, DPP-4

Vildagliptin

T1502

Synonym: NVP-LAF 237,LAF237

Target: Apoptosis, Ferroptosis, Proteasome, DPP-4

Teneligliptin hydrobromide

T6999

Synonym: Teneligliptin hydrobromide anhydrous,MP-513 (hydrobromide)

Target: Others, Proteasome, DPP-4

Gemigliptin

T7369

Synonym: LC15-0444

Target: Proteasome, DPP-4

Trelagliptin

T6237

Synonym: SYR-472

Target: Proteasome, DPP-4

Gemigliptin Tartrate(911637-19-9 free base)

T7369L

Synonym: LC15-0444 tartrate

Target: Proteasome, DPP-4

Anagliptin

T7133

Synonym: SK-0403

Target: Proteasome, DPP-4

Saxagliptin hydrochloride

T6203L

Synonym: BMS477118,Saxagliptin,BMS 477118,Saxagliptin HCl,BMS-477118

Synonym: PHX-1149 free base

Target: Others

(S)-Sitagliptin phosphate

T40930

Synonym: (S)-Sitagliptin phosphate,(S)-MK-0431 phosphate

Target:

Evogliptin HCl

T31732

Synonym: Evogliptin hydrochloride,DA 1229,DA1229,Evogliptin,DA-1229

Target:

Anti-MERS-3A1 mAb

T36652

Synonym: Anti-MERS-3A1 mAb

Target:

Neuropeptide Y (3-36) (human, rat)

NVP-DPP728 dihydrochloride

T39481

Synonym: NVP-DPP728 dihydrochloride

Target:

Prodipine hydrochloride

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00779	DPP4/CD26 Protein, Human, Recombinant	Human	HEK293 Cells
	DPP4/CD26 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 85.4 kDa and the accession number is P27487.
TMPY-00778	DPP4/CD26 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	DPP4/CD26 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 112 kDa and the accession number is P27487.
TMPY-00221	DPP4/CD26 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	DPP4/CD26 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 112.9 kDa and the accession number is P28843.
TMPY-00122	DPP4/CD26 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	DPP4/CD26 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.3 kDa and the accession number is P27487.
TMPH-03279	DPP4/CD26 Protein, Rat, Recombinant (His & SUMO)	Rat	E. coli
	Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, ...
TMPY-04046	DPP4/CD26 Protein, Cynomolgus, Recombinant	Cynomolgus	HEK293 Cells
	DPP4/CD26 Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 84.6 kDa and the accession number is F6VRB0.
TMPY-04251	DPP4/CD26 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	DPP4/CD26 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession number is XP_005573375.1.
TMPY-00074	DPP4/CD26 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	DPP4/CD26 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.9 kDa and the accession number is P28843.
TMPY-03952	DPP4/CD26 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	DPP4/CD26 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 112.9 kDa and the accession number is F6VRB0.
TMPK-00377	DPPIV/CD26 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)	Cynomolgus,Rhesus	HEK293 Cells
	CD26/dipeptidyl peptidase (DPP)IV is a membrane-bound protein found in many cell types of the body, and a soluble form is present in body fluids. There is longstanding evidence that various primary tumors and also metast...
TMPY-06885	SARS-CoV-2 XBB.1.16 (Omicron) Spike S1+S2 trimer Protein (ECD, His)
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;...