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Teneligliptin hydrobromide

Catalog No. T6999 CAS 906093-29-6

Synonyms: MP-513 (hydrobromide), Teneligliptin hydrobromide anhydrous

Teneligliptin is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50 values of approximately 1 nM.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Teneligliptin hydrobromide, CAS 906093-29-6

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Teneligliptin is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50 values of approximately 1 nM.
Targets&IC50	DPP-4:1 nM

Synonyms	MP-513 (hydrobromide), Teneligliptin hydrobromide anhydrous
Molecular Weight	1257.73
Formula	C44H65Br5N12O2S2
CAS No.	906093-29-6

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 100 mg/mL (159.01 mM)

Ethanol: 17 mg/mL (27.03 mM)

H2O: 100 mg/mL (159.01 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Kishimoto M, et al. Diabetes Metab Syndr Obes. 2013, 6:187-95. 2. Sameshima A, et al. J Endocrinol. 2015, 227(1):25-36. 3. Ideta T, et al. Int J Mol Sci. 16(12):29207-18. 4. Pujadas G, et al. Endocrine. 2016, [Epub ahead of print].

Related compound libraries

This product is contained In the following compound libraries：

HIF-1 Signaling Pathway Compound Library Glycometabolism Compound Library Anti-Cancer Metabolism Compound Library Anti-Obesity Compound Library Inhibitor Library Anti-Metabolism Disease Compound Library Drug Repurposing Compound Library Ubiquitination Compound Library Ferroptosis Compound Library Approved Drug Library

Related Products

Related compounds with same targets

Azaleatin Gemigliptin Tartrate(911637-19-9 free base) Gemigliptin Anagliptin Teneligliptin hydrobromide Talabostat mesylate Sitagliptin phosphate Omarigliptin

Dose Conversion

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Teneligliptin hydrobromide 906093-29-6 蛋白酶体泛素化其他 DPP-4 Others Proteasome Teneligliptin MP513 MP 513 Teneligliptin hydrobromide anhydrous Dipeptidyl Peptidase MP-513 (hydrobromide) DPP Inhibitor inhibit MP-513 inhibitor

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