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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60075 | Dopamine D2 receptor agonist-2 | Dopamine D2 Receptor | Dopamine Receptor |
Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) is a ligand targeting the dopamine D2 receptor. | |||
T11077 | Dopamine D2 receptor antagonist-1 | Others | |
Dopamine D2 Receptor Antagonist-1 functions as a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R), demonstrating sub-millimolar affinity. | |||
T7635 | Raclopride | Dopamine Receptor | |
Raclopride is a selective antagonist of dopamine D2/D3 receptor. | |||
T6112 | Doxercalciferol | TSA 840,Hectorol,1.alpha.-Hydroxyvitamin D2,1α-hydroxyvitamin D2 | Others |
Doxercalciferol (TSA 840) is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease. | |||
T1086 | Vitamin D2 | Calciferol,Ergocalciferol,Ercalciol | DNA/RNA Synthesis , Endogenous Metabolite |
Ergocalciferol (Vitamin D2 (Calciferol)) is a derivative of ergosterol formed by ultraviolet rays breaking of the C9-C10 bond with a strong inhibitory effect against bladder tumor promotion by sodium saccharin, and it in... | |||
TQ0084 | Lumateperone Tosylate | ITI-007 | Dopamine Receptor , 5-HT Receptor |
lumateperone Tosylate (ITI-007) is a 5-HT2A receptor antagonist (Ki: 0.54 nM), a SERT blocker (Ki: 61 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki: 32 nM). | |||
T21069 | Lumateperone | ITI 722,ITI722,ITI-007,ITI007 | 5-HT Receptor |
Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM). | |||
T4007 | Eticlopride hydrochloride | Dopamine Receptor | |
Eticlopride, an antipsychotic, is a Selective dopamine D2/D3 receptor antagonist (Ki: 0.5/0.16 nM). | |||
T0280 | Spiperone | Spiroperidol,Spiropitan | Dopamine Receptor |
Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA. | |||
T16392 | ONC206 | Dopamine Receptor | |
ONC206, an analogue of the TRAIL inducer ONC201, acts as a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations and possesses broad-spectrum anti-tumor activity. | |||
T8136 | Perospirone hydrochloride | Perospirone HCl,SM-9018 hydrochloride | Dopamine Receptor , 5-HT Receptor |
Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist. | |||
T2226 | Pergolide mesylate | Pergolide mesylate salt,LY127809,Pergolide methanesulfonate | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Pergolide mesylate salt(LY127809) is a long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEART VALVE DISEASES. | |||
T7943 | Fluphenazine decanoate | Dopamine Receptor | |
Fluphenazine decanoate is dopamine D2 receptor blocke,and is a long-acting phenothiazine neuroleptic that used to treat schizophrenia. | |||
T1045 | Trimipramine maleate | Surmontil maleate | Dopamine Receptor , 5-HT Receptor , Antibacterial , Adrenergic Receptor , Norepinephrine , Histamine Receptor |
Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Mal... | |||
T3431 | Pardoprunox hydrochloride | SLV-308 hydrochloride,DU-126891 hydrochloride | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A recept... | |||
T1069 | Metoclopramide hydrochloride | Maxolon,Metoclopramide HCl | Dopamine Receptor , 5-HT Receptor , AChR |
Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic. | |||
T15686 | L-741626 | 3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole | Dopamine Receptor |
L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3 and D4 receptors respectively). | |||
T12861 | SB-277011 | SB-277011A | Dopamine Receptor |
SB-277011 (SB-277011A) is a specific antagonist of the dopamine D3 receptor with pKi values of 8.0, 6.0, 5.0, and <5.2 for D3 receptor, D2 receptor, 5-HT1D, and 5-HT1B respectively. | |||
T10213 | A-437203 | ABT-925,A37203,Lu201640 | Dopamine Receptor |
A-437203 (Lu201640) is A kind of based on 1 h - pyrimidin - 2 - one sca ff old, selective, new powerful d3 receptor antagonist, on D2, d3, and D4 receptor, Ki value 71, respectively 1.6 and 6220 nM. | |||
T10168 | 5-HT1A modulator 1 | 5-HT1Amodulator1 | Phospholipase , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
5-HT1A modulator 1 displays very high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM). |