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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13572 | Cancer-Targeting Compound 1 | Others | |
Cancer-Targeting Compound 1 can be used in the study of hormone-related cancers, including the treatment or prevention of fibroids, uterine leiomyomas, polycystic ovarian syndrome, or hormone-dependent Cancer, among othe... | |||
T83892 | 33-BCRP Inhibitor | 33-Breast Cancer Resistance Protein Inhibitor | |
33-BCRP inhibitor is a compound that blocks the action of breast cancer resistance protein (BCRP), enhancing the susceptibility of mitoxantrone-resistant H460/MX20 lung cancer cells to the cytotoxic effects of mitoxantro... | |||
T22336 | Galloflavin | Dehydrogenase | |
Galloflavin inhibits both the A and B isoforms of lactate dehydrogenase with Ki of 5.46 µM and 15.06 µM, respectively. Galloflavin is also a potential anticancer agent. | |||
T9929 | Ramucirumab | VEGFR | |
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors. | |||
T9552 | BAZ1A-IN-1 | Epigenetic Reader Domain | |
BAZ1A-IN-1 is a potent BAZ1A inhibitor with the KD value of 0.52 μM for the BAZ1A bromodomain. BAZ1A-IN-1 shows good anti-survival activity against cancer cell lines with high BAZ1A expression, but weak or no activity ag... | |||
T2455 | PFK-015 | PFK15,PFK 015 | Glucokinase , Autophagy |
PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM). | |||
T3755 | Pinostilbene | Others | |
Pinostilbene obviously attenuates the phosphorylation of c-Jun and JNK triggered by 6-OHDA. | |||
TN1046 | Murrayone | Others | |
Murrayone, a coumarin-containing compound derived from M. paniculata, stands out as the most bioactive substance within this species, primarily due to its unique pharmacological attributes that notably suppress cancer me... | |||
T8432 | ASP4132 | AMPK | |
ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity. | |||
T9963 | MPT0B390 | HDAC | |
MPT0B390 is an inhibitor of HDAC and a TIMP3 inducer inhibiting tumor growth, metastasis, and angiogenesis. | |||
TN7020 | Astragenol | Others | |
Astragenol is an intermediate for the synthesis of astragenel derivatives. Astragenol derivatives are promising anti-inflammatory drugs in prostate cancer research. | |||
T60028 | MM41 | DNA/RNA Synthesis | |
MM41 is a human telomeric and gene promoter DNA quadruplex stabilizer with an IC50 of <10 nM against the MIA PaCa-2 pancreatic cancer cell line. | |||
T6816 | DASA-58 | PKM | |
DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator. | |||
T1394 | Ibuprofen | Brufen,(±)-Ibuprofe,Motrin,Advil | COX |
Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resu... | |||
T6540 | Ibuprofen Lysine | Neoprofen | COX |
Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug. | |||
T2325 | Neratinib | HKI-272 | EGFR , HER |
Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively. | |||
T8973 | HS-1793 | Others | |
HS-1793, a resveratrol analogue, downregulates the expression of hypoxia-induced HIF-1 and VEGF and inhibits tumor growth of human breast cancer cells in a nude mouse xenograft model | |||
T41255 | Specific PXR antagonist 70 | Others | |
Specific PXR antagonist 70 is a selective pregnane X receptor (PXR) antagonist with an IC50 of 540 nM and Ki of 390 nM for human PCR and enhances the chemosensitivity of cancer cells. | |||
T8188 | Podophyllotoxone | Others , Microtubule Associated | |
Podophyllotoxinone, a natural compound found in Dysosma versipellis, shows inhibitory activity against L1210 leukemia and KB cells in vitro. | |||
T17258 | WRG-28 | Discoidin Domain Receptor (DDR) | |
WRG-28 is a potent and selective, allosteric discoidin domain receptor 2 (ddr2) inhibitor(IC50 : 230 nM) |