ct1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T62822	CT1-3
	CT1-3 is a potent anti-cancer agent. CT1-3 regulates the JNK/Bcl-2/Bax/XIAP pathway, which induces mitochondria-mediated apoptosis. CT1-3 regulates the E-cadherin/Snail axis to inhibit epithelial mesenchymal transition (...
T27093	CT-1	CT 1	p53
	CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.		p53
T6435	CCT129202		Aurora Kinase
	CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively. It is less potent to FGFR3, GSK3β, PDGFRβ, etc.		Aurora Kinase
T6303	CCT128930		Akt , PKA , S6 Kinase , Autophagy
	CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinase.		Akt , PKA , S6 Kinase , Autophagy
T6303L	CCT128930 hydrochloride	CCT128930 hydrochloride(885499-61-6 Free base)	Apoptosis , Akt , PKA , mTOR , Autophagy
	CCT128930 hydrochloride (CCT128930 hydrochloride) is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. CCT128930 hydrochloride has 28...		Apoptosis , Akt , PKA , mTOR , Autophagy
T14903	CCT129957		Calcium Channel , Phospholipase
	CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells.		Calcium Channel , Phospholipase
T4133	CCT196969		Raf , Src
	CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. It also inhibits SRC, LCK, and the p38 MAPKs.		Raf , Src
T67727	MCT1-IN-3		Monocarboxylate transporter
	MCT1-IN-3 is a monocarboxylate transporter 1 (MCT1) inhibitor. The solute carrier (SLC) monocarboxylate transporter 1 (MCT1; SLC16A1) represents a promising target for the treatment of cancer. MCT1-IN-3 (compound 24) sho...		Monocarboxylate transporter
T79904	PROTAC CDK9/CycT1 Degrader-2		CDK
	PROTAC CDK9/CycT1 Degrader-2 inhibits CDK9 with an IC50 of 45 nM [1].		CDK
T79187	CT1113
	CT1113, a potent inhibitor of both USP28 and USP25, effectively reduces MYC levels in vivo and demonstrates anti-tumor efficacy in a mouse pancreatic cancer CDX model [1].
T26221	MCT1-IN-2	SR13800,SR-13800,SR 13800
	SR13800 is a monocarboxylate transporter 1 (MCT1) inhibitor with cell-permeable.
T70400	CDK9/CycT1-IN-93
	CDK9/CycT1-IN-93 is a highly specific, ATP-competitive inhibitor of CDK9/CycT1 with antiviral activity.

Compounds

CT1-3

T62822

Target: Aurora Kinase

CCT128930

T6303

Synonym:

Target: Akt, PKA, S6 Kinase, Autophagy

CCT128930 hydrochloride

T6303L

Synonym: CCT128930 hydrochloride(885499-61-6 Free base)

Target: Apoptosis, Akt, PKA, mTOR, Autophagy

CCT129957

T14903

Synonym:

Target: Calcium Channel, Phospholipase

Target: Monocarboxylate transporter

PROTAC CDK9/CycT1 Degrader-2

Synonym: SR13800,SR-13800,SR 13800

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-03917	Cardiotrophin 1 Protein, Human, Recombinant	Human	HEK293 Cells
	Cardiotrophin 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 21.2 kDa and the accession number is Q16619-1.
TMPY-00398	Cardiotrophin 1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Cardiotrophin 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q16619-1.
TMPJ-00086	CT-1 Protein, Human, Recombinant (His)	Human	E. coli
	Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate and ovary, and to lower levels in lung, kidney, pancreas, t...
TMPH-02151	OXCT1 Protein, Human, Recombinant (His)	Human	E. coli
	Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of...
TMPY-04316	LECT1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	LECT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.1 kDa and the accession number is O75829-2.