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Search Results for " crt "

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T23917	CRT-0105950	CRT 0105950
	CRT-0105950 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.
T31101	CRT0273750	CRT 0273750,CRT-0273750	PDE
	CRT0273750 regulates plasma LPA levels and is suitable for in vivo studies. CRT0273750 is an autotaxin (ATX) inhibitor with IC50 of 0.014 μM.		PDE
T23916	CRT-0105446	CRT0105446
	CRT-0105446 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.
T10888	CRT0066854 hydrochloride		ROCK , PKC
	CRT0066854 hydrochloride is an effective selective atypical PKCs inhibitor. CRT0066854 is against full-length (FL) PKCι, PKCζ, and ROCK-II kinases with IC50 values of 132 nM, 639 nM, and 620 nM, respectively.		ROCK , PKC
TQ0104	CRT0066101 dihydrochloride		Serine/threonin kinase
	CRT0066101 dihydrochloride is an effective and selective PKD inhibitor (IC50s: 1, 2.5 and 2 nM for PKD1, 2, and 3).		Serine/threonin kinase
T23915	CRT0093964	CRT-0093964,CRT 0093964
	CRT0093964 is a selective AKR1C3 inhibitor.
T23914	CRT0083914	CRT-0083914,CRT 0083914
	CRT0083914 is a potent and selective AKR1C3 inhibitor.
T27089	CRT0066854	CRT0066854 HCl,CRT-0066854 HCl,CRT 0066854,CRT-0066854
	CRT-0066854 is a PKCι and PKCζ inhibitor. CRT0066854 was able to restore polarized morphogenesis in the dysplastic H-Ras spheroids.
T6456	CRT0044876	NSC 69877,7-NO2-ICA,NSC 69877,7-Nitroindole-2-Carboxylic Acid	DNA/RNA Synthesis
	CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.		DNA/RNA Synthesis
T21795	CRT5
	CRT5, a pyrazine benzamide, is a potent and selective PKD inhibitor. The VEGF-induced phosphorylation of three PKD substrates (IC50s = 1, 2, and 1.5 nM for PKD1, PKD2, and PKD3, respectively), histone deacetylase 5, CREB...
T8957	CRT0066101		Serine/threonin kinase
	CRT0066101 is an inhibitor of PKD.		Serine/threonin kinase
T8957L	CRT0066101 dihydrochloride(956121-30-5 free base)		Serine/threonin kinase
	CRT0066101 dihydrochloride is an inhibitor of PKD.		Serine/threonin kinase
T4486	ICRT 14		Wnt/beta-catenin
	iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays of Wnt pathway activity).		Wnt/beta-catenin
T10084	CRTh2 antagonist 1		GPR
	CRTh2 antagonist 1 is a CRTh2 antagonist (IC50: 89 nM).		GPR
T27582	ICRT-5	iCRT 5,iCRT5	Apoptosis , Wnt/beta-catenin
	iCRT-5 is a potent inhibitor of the Wnt pathway. iCRT-5 has antiproliferative activity, blocking Wnt/β-catenin expression and inducing apoptosis. iCRT-5 can be used in the study of multiple myeloma.		Apoptosis , Wnt/beta-catenin
T4302	ICRT3		Apoptosis , Wnt/beta-catenin
	iCRT3 is a Wnt and β-catenin-responsive transcription inhibitor.		Apoptosis , Wnt/beta-catenin
T10889	CRTh2 antagonist 2		GPR
	CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.		GPR
T82667	CRT0063465
	CRT0063465 is a ligand for both human Phosphoglycerate Kinase 1 (PGK1) and the stress sensor protein DJ-1, exhibiting a dissociation constant (Kd) of 24 μM for PGK1. Additionally, it influences the composition of the she...
T10890	CRTh2 antagonist 3		Others
	CRTh2 antagonist 3 is a powerful chemokine receptor homologous molecule expressed on Th2 cell (CRTh2) antagonists. CRTh2 antagonist 3 enhanced the activity of PDK1 on short peptide substrates with EC50 of 2 μM and Kd of ...		Others
T10891	CRTH2-IN-1	Ramatroban analog	P450
	CRTH2-IN-1 is a selective prostaglandin D2 receptor DP2 (CRTH2) antagonist, a Ramatroban analog, with an IC50 of 6 nM in the human DP2 binding assay.		P450

Compounds

CRT-0105950

T23917

Synonym: CRT 0105950

Target:

CRT0273750

T31101

Synonym: CRT 0273750,CRT-0273750

Target: PDE

CRT-0105446

T23916

Synonym: CRT0105446

Target:

CRT0066854 hydrochloride

T10888

Synonym:

Target: ROCK, PKC

CRT0066101 dihydrochloride

TQ0104

Synonym:

Target: Serine/threonin kinase

CRT0093964

T23915

Synonym: CRT-0093964,CRT 0093964

Target:

CRT0083914

T23914

Synonym: CRT-0083914,CRT 0083914

Target:

CRT0066854

T27089

Synonym: CRT0066854 HCl,CRT-0066854 HCl,CRT 0066854,CRT-0066854

Target:

CRT0044876

T6456

Synonym: NSC 69877,7-NO2-ICA,NSC 69877,7-Nitroindole-2-Carboxylic Acid

Target: DNA/RNA Synthesis

Target: Serine/threonin kinase

CRT0066101 dihydrochloride(956121-30-5 free base)

T8957L

Synonym:

Target: Serine/threonin kinase

iCRT 14

T4486

Synonym:

Target: Wnt/beta-catenin

Synonym: iCRT 5,iCRT5

Target: Apoptosis, Wnt/beta-catenin

iCRT3

T4302

Synonym:

Target: Apoptosis, Wnt/beta-catenin

Synonym: Ramatroban analog

Target: P450

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-03258	Calreticulin Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Calreticulin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73 kDa and the accession number is P27797.
TMPY-06327	Calreticulin Protein, Human, Recombinant	Human	HEK293 Cells
	Calreticulin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.99 kDa and the accession number is P27797.
TMPY-00317	Calcitonin receptor Protein, Human, Recombinant (aa 25-154, hFc)	Human	HEK293 Cells
	Calcitonin receptor Protein, Human, Recombinant (aa 25-154, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.9 kDa and the accession number is P30988-1.
TMPY-00085	Calcitonin receptor Protein, Human, Recombinant (aa 1-153, hFc)	Human	HEK293 Cells
	Calcitonin receptor Protein, Human, Recombinant (aa 1-153, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.1 kDa and the accession number is P30988-2.
TMPY-03259	Calreticulin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Calreticulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.4 kDa and the accession number is P27797.
TMPH-00436	Calreticulin Protein, Cricetulus griseus, Recombinant (His)	Chinese hamster	P. pastoris (Yeast)
	Calreticulin Protein, Cricetulus griseus, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 48.1 kDa and the accession number is Q8K3H7.
TMPH-03105	Calreticulin Protein, Pig, Recombinant (His)	Sus scrofa (Pig)	P. pastoris (Yeast)
	Calreticulin Protein, Pig, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 48.6 kDa and the accession number is P28491.
TMPH-02559	Calreticulin Protein, Mouse, Recombinant (GST)	Mouse	E. coli
	Calreticulin Protein, Mouse, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 73.3 kDa and the accession number is P14211.
TMPH-02558	Calreticulin Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	Calreticulin Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 48.3 kDa and the accession number is P14211.
TMPJ-01277	CRT2 Protein, Human, Recombinant	Human	E. coli
	Calreticulin-3 belongs to the calreticulin family, members of which are calcium binding chaperones localized mainly in the endoplasmic reticulum. It can be divided into a N-terminal globular domain, a proline-rich P-doma...
TMPK-00623	CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid...
TMPY-01674	CRTAM Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cytotoxic and regulatory T-cell molecule, also known as Class-I MHC-restricted T-cell-associated molecule and CRTAM, is a single-pass type I membrane protein which belongs to thenectin family.CRTAM contains oneIg-like...
TMPJ-00233	CD200R1/CRTR2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain ...
TMPK-01262	CD200R1/CRTR2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid...
TMPH-03083	CrtX Protein, Pantoea ananas, Recombinant (His & Myc)	Pantoea ananas	Baculovirus Insect Cells
	Catalyzes the glycosylation reaction which converts zeaxanthin to zeaxanthin bis(beta-D-glucoside). The reaction proceeds in two steps with the monoglucoside as an intermediate. CrtX Protein, Pantoea ananas, Recombinant ...
TMPK-00971	CRTAM Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of I...
TMPJ-01422	CRTAM Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	CRTAM Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 50-60 KDa and the accession number is XP_005580021.1.
TMPK-01385	CRTAM Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of I...
TMPK-00624	CD200R1/CRTR2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid...
TMPJ-00429	CRTAM Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	CRTAM Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 80-90 KDa and the accession number is A0A2K5TKL4.
TMPH-03084	CrtX Protein, Pantoea ananas, Recombinant (E. coli, His & Myc)	Pantoea ananas	E. coli
	Catalyzes the glycosylation reaction which converts zeaxanthin to zeaxanthin bis(beta-D-glucoside). The reaction proceeds in two steps with the monoglucoside as an intermediate. CrtX Protein, Pantoea ananas, Recombinant ...
TMPY-05059	LACRT Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LACRT Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.7 kDa and the accession number is Q9GZZ8.
TMPK-00622	CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid...