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Search Results for " c26 "

20

Compounds

Cat No. Product Name Synonyms Targets
T38286 C26 Sphingomyelin (d18:1/26:0) C26 Sphingomyelin (d18:1/26:0)
C26 Sphingomyelin is a sphingolipid that has been found in serum and cell or brain extracts.1,2,3C26 sphingomyelin levels are increased in the serum of patients with hemophagocytic lymphohistiocytosis, an inflammatory co...
T69333 LX-5
LX-5 is a selective activator of the p38 mitogen-activated protein kinase (MAPK) pathway. LX-5 de-represses a subset of endogenous genes repressed by DNA methylation.
T1520 Aliskiren hemifumarate CGP 60536,SPP 100,CGP60536B RAAS , Autophagy
Aliskiren hemifumarate (CGP60536B) is an orally active nonpeptide renin inhibitor with antihypertensive activity.
T29541 AC265347 AC-265347 CaSR
AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity that inhibits neuroblastoma tumour growth by inducing differentiation.AC265347 can be used to stud...
T72054 SLC26A3-IN-1 transporter
SLC26A3-IN-1 is an inhibitor of the anion-exchange protein SLC26A3 with an IC50 value of 340 nM.SLC26A3 is a solute carrier (SLC) protein and a member of the SLC26 family, which has a wide range of anionic specificities ...
T7127 DC260126 Apoptosis , GPR
DC260126 is a small-molecule antagonist of FFA1 (GPR40)
T11141 E64FC26 Others
E64FC26 is a potent protein disulfide isomerase (PDI) family pan-inhibitor with antitumor activity, inhibits PDIA1, PDIA3, PDIA4, TXNDC5 and PDIA6, and can be used in the study of multiple myeloma and pancreatic cancer.
T2440 IC261 SU-5607 Apoptosis , Casein Kinase , CDK
IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.
T78579 NSC260594
NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-regulation of Wnt signaling proteins. Additionally, it can identi...
T74815 SLC26A3-IN-2
SLC26A3-IN-2 is an orally active compound that functions as an inhibitor of the anion exchanger protein SLC26A3, displaying an IC50 of 360 nM. This protein is a member of the solute carrier (SLC) family, specifically the...
T35874 CC260
CC260, a selective inhibitor for PI5P4Kα and PI5P4Kβ with Kis of 40 nM and 30 nM respectively, exhibits minimal to no inhibition against other protein kinases like Plk1 and RSK2. It is applicable in the research of cell ...
T14092 AC260584 Others
AC260584 is an M1 muscarinic receptor allosteric agonist (pEC50: 7.6).
T33753 NSC265473 NSC-265473,NSC-305458,NSC305458,NSC 265473,NSC 305458
NSC265473 is an ABCG2 substrate.
T39757 EC2629 EC2629
EC2629 is a highly potent folate- receptor-targeted DNA crosslinking agent.
T71190 FLC26
FLC26 is a CK2 inhibitor with IC50 = 9 nM
T60942 MC2652
MC2652 (compound 1a) is a potent LSD1 inhibitor that shows high inhibitory effects in leukaemia cells MV4-11 and NB4. MC2652 has antiproliferative activity against LNCaP cells of prostate cancer [1].
T78604 SLC26A3-IN-3
SLC26A3-IN-3 (compound 4az), a potent SLC26A3 inhibitor with an IC50 of 40 nM, is utilized for constipation and cystic fibrosis research [1].
T39812 (E/Z)-E64FC26 (E/Z)-E64FC26
(E/Z)-E64FC26 is a mixture complex comprising E-E64FC26 and Z-E64FC26. E-E64FC26 is a highly potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC50 values of 1.9, 20.9, 25.9, 16.3, and 25.4 μM ag...
T60627 ELOVL1-IN-2 Others
ELOVL1-IN-2, a compound known as an inhibitor of the elongation of very long chain fatty acid 1 (ELOVL1) enzyme, exhibits a weak inhibitory effect on ELOVL1 (with an IC50 of 21 μM) and demonstrates moderate potency in a ...
T3844 Deltonin ERK , Others , Akt , Endogenous Metabolite
Deltonin has an inhibition of ERK1/2 and AKT activation. Deltonin shows cytotoxicity against human HepG2 cells (IC50: 7.66 μM), mouse C26 cells (IC50: 1.22 μM), and human MDA-MB-231 cells (IC50: 1.58 μM).
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