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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T38286 | C26 Sphingomyelin (d18:1/26:0) | C26 Sphingomyelin (d18:1/26:0) | |
C26 Sphingomyelin is a sphingolipid that has been found in serum and cell or brain extracts.1,2,3C26 sphingomyelin levels are increased in the serum of patients with hemophagocytic lymphohistiocytosis, an inflammatory co... | |||
T69333 | LX-5 | ||
LX-5 is a selective activator of the p38 mitogen-activated protein kinase (MAPK) pathway. LX-5 de-represses a subset of endogenous genes repressed by DNA methylation. | |||
T1520 | Aliskiren hemifumarate | CGP 60536,SPP 100,CGP60536B | RAAS , Autophagy |
Aliskiren hemifumarate (CGP60536B) is an orally active nonpeptide renin inhibitor with antihypertensive activity. | |||
T29541 | AC265347 | AC-265347 | CaSR |
AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity that inhibits neuroblastoma tumour growth by inducing differentiation.AC265347 can be used to stud... | |||
T72054 | SLC26A3-IN-1 | transporter | |
SLC26A3-IN-1 is an inhibitor of the anion-exchange protein SLC26A3 with an IC50 value of 340 nM.SLC26A3 is a solute carrier (SLC) protein and a member of the SLC26 family, which has a wide range of anionic specificities ... | |||
T7127 | DC260126 | Apoptosis , GPR | |
DC260126 is a small-molecule antagonist of FFA1 (GPR40) | |||
T11141 | E64FC26 | Others | |
E64FC26 is a potent protein disulfide isomerase (PDI) family pan-inhibitor with antitumor activity, inhibits PDIA1, PDIA3, PDIA4, TXNDC5 and PDIA6, and can be used in the study of multiple myeloma and pancreatic cancer. | |||
T2440 | IC261 | SU-5607 | Apoptosis , Casein Kinase , CDK |
IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM. | |||
T78579 | NSC260594 | ||
NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-regulation of Wnt signaling proteins. Additionally, it can identi... | |||
T74815 | SLC26A3-IN-2 | ||
SLC26A3-IN-2 is an orally active compound that functions as an inhibitor of the anion exchanger protein SLC26A3, displaying an IC50 of 360 nM. This protein is a member of the solute carrier (SLC) family, specifically the... | |||
T35874 | CC260 | ||
CC260, a selective inhibitor for PI5P4Kα and PI5P4Kβ with Kis of 40 nM and 30 nM respectively, exhibits minimal to no inhibition against other protein kinases like Plk1 and RSK2. It is applicable in the research of cell ... | |||
T14092 | AC260584 | Others | |
AC260584 is an M1 muscarinic receptor allosteric agonist (pEC50: 7.6). | |||
T33753 | NSC265473 | NSC-265473,NSC-305458,NSC305458,NSC 265473,NSC 305458 | |
NSC265473 is an ABCG2 substrate. | |||
T39757 | EC2629 | EC2629 | |
EC2629 is a highly potent folate- receptor-targeted DNA crosslinking agent. | |||
T71190 | FLC26 | ||
FLC26 is a CK2 inhibitor with IC50 = 9 nM | |||
T60942 | MC2652 | ||
MC2652 (compound 1a) is a potent LSD1 inhibitor that shows high inhibitory effects in leukaemia cells MV4-11 and NB4. MC2652 has antiproliferative activity against LNCaP cells of prostate cancer [1]. | |||
T78604 | SLC26A3-IN-3 | ||
SLC26A3-IN-3 (compound 4az), a potent SLC26A3 inhibitor with an IC50 of 40 nM, is utilized for constipation and cystic fibrosis research [1]. | |||
T39812 | (E/Z)-E64FC26 | (E/Z)-E64FC26 | |
(E/Z)-E64FC26 is a mixture complex comprising E-E64FC26 and Z-E64FC26. E-E64FC26 is a highly potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC50 values of 1.9, 20.9, 25.9, 16.3, and 25.4 μM ag... | |||
T60627 | ELOVL1-IN-2 | Others | |
ELOVL1-IN-2, a compound known as an inhibitor of the elongation of very long chain fatty acid 1 (ELOVL1) enzyme, exhibits a weak inhibitory effect on ELOVL1 (with an IC50 of 21 μM) and demonstrates moderate potency in a ... | |||
T3844 | Deltonin | ERK , Others , Akt , Endogenous Metabolite | |
Deltonin has an inhibition of ERK1/2 and AKT activation. Deltonin shows cytotoxicity against human HepG2 cells (IC50: 7.66 μM), mouse C26 cells (IC50: 1.22 μM), and human MDA-MB-231 cells (IC50: 1.58 μM). |