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11

Compounds

Cat No. Product Name Synonyms Targets
T13099 TC ASK 10 ASK , MAPK
TC ASK 10 is a potent, selective and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1)(IC50 of 14 nM).
T22254 Alflutinib AST2818,ASK120067 EGFR , P450
Alflutinib (ASK120067) is an inhibitor of EGFR, and its targets including EGFR activating mutations and T790M, thus leading to tumor growth inhibition.
T9697 ASK1-IN-1 ASK
ASK1-IN-1 is an inhibitor of apoptosis signal-regulating kinase 1 which is a key mediator in the apoptotic and inflammatory cellular stress response with an IC50 of 21 nM in biochemica assays.
T35897 ASK120067
ASK120067 is a potent and orally active inhibitor of EGFRT790M (IC50:0.3 nM) with selectivity over EGFRWT (IC50:6.0 nM). ASK120067 is a third-generation EGFR-TKI for the research of non-small cell lung cancer (NSCLC)[1]...
T9377 ASK1-IN-2 Apoptosis , ASK , MAPK
ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can potentially be used as a therapeutic strategy for ulcerative colitis[1].
T67857 ASK1-IN-4 ASK
ASK1-IN-4 is an ASK1 inhibitor, IC50 = 0.2 μM.
T72064 TASK-1-IN-1 Potassium Channel
TASK-1-IN-1 is a potent and selective inhibitor of TASK-1 (Potassium Channel) (IC50: 148 nM).TASK-1-IN-1 has a reduced inhibitory effect on the TASK-3 channel with an IC50 of 1750 nM.TASK-1-IN-1 has anticancer effects.
T73221 CASK-IN-1
CASK-IN-1 is a highly potent and selective CASK inhibitor with a K d value of 0.022 μM.
T61584 ASK1-IN-3
ASK1-IN-3 is a highly potent and selective inhibitor of ASK1 kinase, demonstrating an IC 50 of 33.8 nM. This compound also exhibits inhibitory effects on various cell cycle regulating kinases. ASK1-IN-3 showcases remarka...
T22418 S-99 Others
S-99 is a high purity chemical that targets ASK and is important for Immunology, Inflammation, Cancer research.
TN4635 Neoechinulin A NADPH-oxidase , Beta Amyloid , ASK , IκB/IKK , p38 MAPK , TNF , NOS , NF-κB , COX , Prostaglandin Receptor
Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, it may block the phosphorylation of mitogen-activated protein kinase (MAPK) ...
TargetMol