a-6 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN1149	6''-O-acetylsaikosaponin A		Others
	6''-O-acetylsaikosaponin A is an acetyl saikosaponin isolated from the roots of Bupleurum chinense. Itshows some osteoclast-inhibiting activities		Others
T26629	Angstrom6	A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide	PAI-1
	Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascade and abrogates the downstream effects.Angstrom6 has antitumor a...		PAI-1
T9553	8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxylic acid		Others
	8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-car is a H+/K+ ATPase inhibitor with IC50 of 0.38μM.		Others
T64393	6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile		Others
	6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile is a biologically active compound, which is utilize...		Others
T9837	N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bromoaniline		ALK
	Compound 12d is a potent ALK5 inhibitor with an IC50 of 7nM.		ALK
TN1304	6-Formyl-isoophiopogonanone A	6-Aldehydoisoophiopogonanone A	Others
	6-Aldehydoisoophiopogonanone A is a natural product from Ophiopogon japonicus.		Others
TN5470	6-Aldehydo-isoophiopogonone A
	6-Aldehydo-isoophiopogonone A is a natural product of Ophiopogon, Liliaceae. The catalog number is TN5470 and the CAS number is 112500-90-0. 6-Aldehydo-isoophiopogonone A can be used as a reference standard.
TN3158	6-Demethoxycleomiscosin A		Others
	6-Demethoxycleomiscosin A is a natural product for research related to life sciences. The catalog number is TN3158 and the CAS number is 121587-20-0.		Others
T6S1315	Oroxylin A	6-Methoxybaicalein,Baicalein 6-methyl ether	Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
	1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v...		Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
T5S2204	Sibiricose A6		Antioxidant
	1. Sibiricose A6 displays antidepressant-like action, it may prevent or relieve depression. 2. Sibiricose A6 shows potent antioxidant activity.		Antioxidant
T3265	Azathramycin	Desmethyl Azithromycin,6-Demethylazithromycin,Azaerythromycin A,Azaerythromycin	Antibacterial , Antibiotic
	Azathramycin (Desmethyl Azithromycin) is an antibiotic derived from erythromycin, binding to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA.		Antibacterial , Antibiotic
T10165L	5-A-RU hydrochloride	5-Amino-6-(D-ribitylamino)uracil hydrochloride	Others
	5-A-RU hydrochloride (5-Amino-6-(D-ribitylamino)uracil hydrochloride) is an intermediate of bacterial riboflavin that activates mucosal-associated invariant T cells (MAIT).5-A-RU is used in the study of breast and prosta...		Others
TN3157	6-Demethoxy-9'-deoxycleomiscosin A		Others
	6-Demethoxy-9'-deoxycleomiscosin A is a natural product for research related to life sciences. The catalog number is TN3157 and the CAS number is 121587-18-6.		Others
T76341L	[DPro10] Dynorphin A (1-11)acetate,porcine	[DPro10] Dynorphin A (1-11)acetate,porcine(94596-26-6 Free base)	Opioid Receptor
	[DPro10] Dynorphin A (1-11)acetate,porcine is a highly potent κ-opioid receptor agonist with a Ki value of 0.13 nM. [DPro10] Dynorphin A (1-11), porcine is an n-alkylated derivative with analgesic activity.		Opioid Receptor
T3S0737	Flavokawain A	Flavokavain A	Apoptosis , p38 MAPK
	NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significant...		Apoptosis , p38 MAPK
TN3068	4\|A,6\|A-Dihydroxyeudesm-11(13)-en-12,8\|A-olide	4alpha,6alpha-Dihydroxyeudesm-11(13)-en-12,8beta-olide	Others
	4\|A,6\|A-Dihydroxyeudesm-11(13)-en-12,8\|A-olide is a natural product for research related to life sciences. The catalog number is TN3068 and the CAS number is 35001-19-5.		Others
T60098	MSC2504877	3-(4-(2-Hydroxypropan-2-yl)phenyl)-6-methylpyrrolo[1,2-a]pyrazin-1(2H)-one	Others
	MSC2504877 is an inhibitor of tankyrase and enhances the effects of clinical CDK4/6 inhibitors. MSC2504877 suppresses the upregulation of Cyclin D2 and Cyclin E2 caused by palbociclib and enhances the suppression of phos...		Others
T3885	ROSIRIDIN	6'-O-Deacetylrosiridoside C,(-)-Rosiridin	Others , Monoamine Oxidase
	Rosiridin (6'-O-Deacetylrosiridoside C) has cardioprotective activity.		Others , Monoamine Oxidase
T5120	Rhamnose	6-Deoxyhexopyranose,6-Deoxy-L-mannose,alpha-L-Rhamnose	Calcium Channel , Endogenous Metabolite
	Addition of the Rhamnose (6-Deoxy-L-mannose)-rich polysaccharide, RROP-1, to normal human dermal fibroblasts (NHDFs) and human endothelial cells produced a dose-dependent stimulation of the calcium-signaling pathway, ind...		Calcium Channel , Endogenous Metabolite
T7662	α-Demethylnaproxen		COX
	α-Demethylnaproxen is a competitive inhibitor of COX(Ki values of 21 and 19 μM for ovine COX-1 and -2, respectively)		COX