a-002 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T17218	Varespladib methyl	A-002,LY333013	Others , Phospholipase
	Varespladib methyl (LY333013), a bioavailable prodrug of Varespladib, is a selective group II secretory phospholipase A2 inhibitor.		Others , Phospholipase
T6073	OG-L002		Histone Demethylase , Monoamine Oxidase , HSV
	OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.		Histone Demethylase , Monoamine Oxidase , HSV
T7813	α-MSH	MSH, amide,CZEN-002,α-Melanocyte-Stimulating Hormone (MSH), amide	Melanocortin Receptor , Adenylyl cyclase
	α-MSH (MSH, amide) is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.		Melanocortin Receptor , Adenylyl cyclase
T19699	Triciribine phosphate	TCN-P,VD 002,VQD-002	Apoptosis , Akt
	Triciribine phosphate (VD 002) is a highly selective AKT inhibitor that induces cell cycle arrest and cysteinyl asparagin-dependent apoptosis, inhibits neovascularization, and can be used in the study of leukemia.		Apoptosis , Akt
T9321	Zapnometinib	ATR-002,3,4-difluoro-2-(2-chloro-4-iodophenylaMino)-benzoic acid,PD0184264,2-(2-chloro-4-iodoanilino)-3,4-difluorobenzoic acid	Influenza Virus , MEK , Antibacterial
	Zapnometinib (ATR-002) is a MEK inhibitor.		Influenza Virus , MEK , Antibacterial
T10198	8-M-PDOT	8-Methoxy-2-propionamidotetralin,AH-002	MT Receptor
	8-M-PDOT (AH-002) is a selective and potent melatonin MT2 receptor agonist that also inhibits MT1 receptors.8-M-PDOT has anxiolytic activity and may be used to study MT2-induced neuropathic pain.		MT Receptor
T28502	Ralaniten	EPI-002	Androgen Receptor
	Ralaniten (EPI-002) is a potent, specific, and orally active antagonist of the androgen receptor N-terminal structural domain (AR-NTD).Ralaniten inhibits AR transcriptional activity with an IC50 value of 7.4 μM.Ralanites...		Androgen Receptor
T39190	ATX-002
	ATX-002 is a property-tunable lipid for RNA drug delivery.
T62496	IST5-002
	IST5-002 is a potent inhibitor of Stat5a/b and selectively inhibits the transcriptional activity of Stat5a/b with IC50 values of 1.5 μM and 3.5 μM for Stat5a and Stat5b, respectively. IST5-002 can be used to study prosta...
T63860	PRMT5-IN-18
	PRMT5-IN-18 (Compound 002) is a potent inhibitor of PRMT5 and can be used in the study of PRMT5-mediated diseases, such as tumours.
T60305	ZLc-002
	ZLc-002 is a selective small-molecule inhibitor of nNOS-Capon coupling. ZLc-002 suppresses inflammatory nociception and chemotherapy-induced neuropathic pain. ZLc-002 can be used in anxiety disorder and inflammation rese...
T13343	20-HEDE	WIT 002	Others
	20-HEDE (WIT 002) is a 20-hydroxyeicosatetraenoic acid (20-HETE) antagonist.		Others
T10517	BET-BAY 002 (S enantiomer)		Others
	The S-enantiomer of BET-BAY 002, referred to as BET-BAY 002 S enantiomer, is a potent inhibitor of BET (Bromodomain and Extra-Terminal motif proteins).		Others
T10518	BET-BAY 002		Others
	BET-BAY 002 is an effective BET inhibitor and exhibits efficacy in a multiple myeloma model.		Others
T39586	Cantrixil	TRX-E-002-1
	Cantrixil (TRX-E-002-1) is a second-generation super-benzopyran (SBP) compound, derived from TRX-E-002. It elicits an increase in phosphorylated c-Jun levels, leading to caspase-mediated apoptosis in ovarian cancer cells...
T76889	Prasinezumab
	Prasinezumab (PRX 002), a humanized IgG1 monoclonal antibody targeting aggregated α-synuclein, shows promise for Parkinson's disease research [1].
T74367	SC209
	SC209, an ADC cytotoxin is used in synthesis of anti- EGFR antibody-drug conjugate ADC. SC209 is a metabolite of STRO-002 [1] [2] .
T77136	Quisovalimab
	Quisovalimab (AVTX-002; AEVI 002; SAR 252067), a human monoclonal antibody targeting LIGHT, a tumor necrosis factor (TNF)-related cytokine (TNFSF14), is crucial for managing acute respiratory distress syndrome (ARDS) and...
T72866	(Rac)-ZLc-002
	(Rac)-ZLc-002 is a compound that inhibits the interaction between neuronal nitric oxide synthase (nNOS) and the nitric oxide synthase 1 adaptor protein (NOS1AP), effectively reducing inflammatory pain and chemotherapy-in...
T69766	Gusacitinib HCl
	Gusacitinib, also known as ASN-002 and EN-3351, is a potent dual inhibitor of SYK/JAK kinases. ASN002 showed strong antitumor activity in both hematological and solid tumor xenograft models. ASN002 strongly suppressed ...