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α-MSH

Catalog No. T7813 CAS 581-05-5

Synonyms: 美拉诺坦, MSH, amide, CZEN-002, α-Melanocyte-Stimulating Hormone (MSH), amide

α-MSH is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.

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α-MSH, CAS 581-05-5

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

α-MSH is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.

Synonyms	美拉诺坦, MSH, amide, CZEN-002, α-Melanocyte-Stimulating Hormone (MSH), amide
Molecular Weight	1664.91
Formula	C77H109N21O19S
CAS No.	581-05-5

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 10mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Jo H, et al. Synthesis and biological evaluation of caffeic acid derivatives as potent inhibitors of α-MSH-stimulated melanogenesis. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3374-3377. 1. Lu X Y , Barsh G S , Akil H , et al. Interaction between α-melanocyte-stimulating hormone and corticotropin-releasing hormone in the regulation of feeding and hypothalamo-pituitary-adrenal responses[J]. Journal of Neuroscience the Official Journal of the Society for Neuroscience, 2003, 23(21):7863. 2. Jo H , Choi M , Sim J , et al. Synthesis and Biological Evaluation of Caffeic Acid Derivatives as Potent Inhibitors of α-MSH-stimulated Melanogenesis[J]. Bioorganic & Medicinal Chemistry Letters, 2017:S0960894X17306133.

Related compound libraries

This product is contained In the following compound libraries：

Peptide Compound Library Bioactive Compound Library

Related Products

Related compounds with same targets

α-MSH AC1-IN-1 Forskolin ST034307 NKY80 NB001 LRE1 2',5'-Dideoxyadenosine

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

α-MSH 581-05-5 G蛋白偶联受体神经科学 Adenylyl cyclase Melanocortin Receptor hormone αMSH α-Melanocyte-Stimulating Hormone (MSH), amide inhibit Inhibitor α MSH neuroimmunomodulatory inflammation MSH, amide CZEN-002 endogenous MC Receptor peptide anti-inflammatory inhibitor

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