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beta-Amyrone

Catalog No. TN3500   CAS 638-97-1
Synonyms: β-Amyron

beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits anti-α-glucosidase inhibitory activity and moderate AChE activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity.

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beta-Amyrone Chemical Structure
beta-Amyrone, CAS 638-97-1
Pack Size Availability Price/USD Quantity
1 mg In stock $ 122.00
5 mg In stock $ 372.00
10 mg In stock $ 597.00
25 mg In stock $ 935.00
50 mg In stock $ 1,260.00
100 mg In stock $ 1,690.00
500 mg In stock $ 3,380.00
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Purity: 99.55%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits anti-α-glucosidase inhibitory activity and moderate AChE activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity.
In vitro beta-Amyrone inhibits α-glucosidase AChE and fungal activity with IC50 values of 25 μM, 23 μM and 8 μg/mL, respectively[1]. In LPS-stimulated J774 cells, beta-Amyrone (2.5, 5, 10 μg/mL) inhibits NO production with an IC50 value of 4.61 μg/mL without obvious effects on cell viability[4]. beta-Amyrone (10 μg/mL) inhibits IL-6, IL-10 levels, and COX-2 expression at the dose of 10 μg/mL[4].
In vivo In ear phenol-induced edema in Balb C mice, beta-Amyrone (0.1, 0.3, 0.6 mg/kg) inhibits ear edema formation in a dose-related manner[4].
Source
Synonyms β-Amyron
Molecular Weight 424.7
Formula C30H48O
CAS No. 638-97-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Insoluble

TargetMolReferences and Literature

1. Bourjot M, et al. Chemical constituents of Anacolosa pervilleana and their antiviral activities. Fitoterapia. 2012 Sep;83(6):1076-80. 2. Athar Ata, et al. Chemical constituents of Drypetes gossweileri and their enzyme inhibitory and anti-fungal activities. Phytochem. Lett., 2011, 4(1):34-7. 3. Hassabelrasoul Elfadil, et al. The In Vitro Antifungal Activity of Sudanese Medicinal Plants against Madurella mycetomatis, the Eumycetoma Major Causative Agent. PLoS Negl Trop Dis. 2015 Mar; 9(3): e0003488. 4. Patrícia D O de Almeida, et al. Anti-Inflammatory Activity of Triterpenes Isolated from Protium paniculatum Oil-Resins. Evid Based Complement Alternat Med. 2015;2015:293768. 5. Ki-Kwang Oh, et al. Elucidating Drug-Like Compounds and Potential Mechanisms of Corn Silk ( Stigma Maydis) against Obesity: A Network Pharmacology Study. Curr Issues Mol Biol. 2021 Nov 6;43(3):1906-1936.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Breast Cancer Compound Library Bioactive Compounds Library Max Neurotransmitter Receptor Compound Library Nuclear Receptor Compound Library Natural Product Library for HTS Anti-Prostate Cancer Compound Library Selected Plant-Sourced Compound Library Bioactive Compound Library Natural Product Library Anti-Colorectal Cancer Compound Library

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Keywords

beta-Amyrone 638-97-1 DNA Damage/DNA Repair Immunology/Inflammation Metabolism Microbiology/Virology Neuroscience COX AChR PPAR Antifection antifungal AChE COX-2 PI3K-Akt Anti-inflammatory Fungal inflammation β-Amyron beta-Amyron β-Amyrone CHIKV Cyclooxygenase b-Amyron inhibit Inhibitor infection obesity Peroxisome proliferator-activated receptors b-Amyrone inhibitor

 

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