keep away from moisture,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Zeylenone, a cyclohexene oxide from Uvaria grandiflora, has antitumour and antiproliferative activity, inhibiting cervical cancer cell proliferation and inducing apoptosis through the PI3K/AKT/mTOR and MAPK/ERK signalling pathways.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 598.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 928.00 |
Description | Zeylenone, a cyclohexene oxide from Uvaria grandiflora, has antitumour and antiproliferative activity, inhibiting cervical cancer cell proliferation and inducing apoptosis through the PI3K/AKT/mTOR and MAPK/ERK signalling pathways. |
In vitro | Zeylenone (zey), a cyclohexene oxide compound, exerted an obvious inhibitory effect on several cancer cell lines and exhibited little cytotoxicity towards normal cells, enabling zey to play a unique role in combination therapy.we found that zey potentiated the anti-osteosarcoma efficacy of cisplatin and exhibited synergistic interactions with cisplatin in vitro, which also were confirmed in vivo by using xenograft model[1]. |
Molecular Weight | 382.36 |
Formula | C21H18O7 |
CAS No. | 193410-84-3 |
keep away from moisture,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Zeylenone 193410-84-3 Apoptosis Cytoskeletal Signaling MAPK PI3K/Akt/mTOR signaling mTOR PI3K Akt ERK inhibitor inhibit