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Nicardipine

Name: Nicardipine
Brand: TargetMol
SKU: T21454
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T21454Cas No. 55985-32-5

Alias Flusemide, Dagan, Cardene, Antagonil

Nicardipine (Cardene), a calcium channel blockers belonging to the dihydropyridine class, is a drug used to treat angina and high blood pressure.

Nicardipine

🥰Excellent

Purity: 99.56%

Catalog No. T21454Alias Flusemide, Dagan, Cardene, AntagonilCas No. 55985-32-5

Nicardipine (Cardene), a calcium channel blockers belonging to the dihydropyridine class, is a drug used to treat angina and high blood pressure.

Pack Size	Price	Availability	Quantity
100 mg	$29	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.56%

Resource Download

COA HPLC LCMS HNMR

Product Introduction

Bioactivity

Description	Nicardipine (Cardene), a calcium channel blockers belonging to the dihydropyridine class, is a drug used to treat angina and high blood pressure.
Targets&IC50	Ca2+ channel (Cardiac):1 μM (IC50)
Synonyms	Flusemide, Dagan, Cardene, Antagonil

Chemical Properties

Molecular Weight	479.52
Formula	C₂₆H₂₉N₃O₆
Cas No.	55985-32-5
Smiles	COC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OCCN(C)Cc1ccccc1
Relative Density.	1.230 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: Insoluble

DMSO: 60 mg/mL (125.13 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0854 mL	10.4271 mL	20.8542 mL	104.2709 mL
5 mM	0.4171 mL	2.0854 mL	4.1708 mL	20.8542 mL
10 mM	0.2085 mL	1.0427 mL	2.0854 mL	10.4271 mL
20 mM	0.1043 mL	0.5214 mL	1.0427 mL	5.2135 mL
50 mM	0.0417 mL	0.2085 mL	0.4171 mL	2.0854 mL
100 mM	0.0209 mL	0.1043 mL	0.2085 mL	1.0427 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

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