Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nelfinavir Mesylate (Viracept) is an effective HIV protease inhibitor (Ki: 2 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 48.00 | |
10 mg | In stock | $ 74.00 | |
25 mg | In stock | $ 157.00 | |
50 mg | In stock | $ 266.00 | |
100 mg | In stock | $ 397.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 72.00 |
Description | Nelfinavir Mesylate (Viracept) is an effective HIV protease inhibitor (Ki: 2 nM). |
Targets&IC50 | HIV protease:2 nM(Ki) |
Kinase Assay | GTPγ[35S] binding assay: The cells are homogenized and centrifuged at 26900 × g for 30 min at 4°C. Membranes are re-suspended in 20 mM HEPES (pH 7.4), 100 mM NaCl, 10 mM MgCl2, 1 mM EDTA and 0.1% fat-free BSA at 2–3 mg protein/mL. GTPγ[35S] binding assay is performed with the membranes (75 mg protein /mL in 50 mM HEPES, 100 mM NaCl, 10 mM MgCl2, 20 μg/mL saponin and 0.1% fat-free BSA (pH 7.4), 5 mg/mL with wheat-germ agglutinin-coated scintillation proximity assay-bead, and 10 μM GDP for 10–15 min. The GTPγ[35S]-binding reaction is started by the addition of 200 pM GTPγ[35S]. After 120 min at room temperature, the plates are centrifuged for 10 min at 300 × g and counted. |
Synonyms | Viracept, Nelfin, AG1343, AG 1343 Mesylate |
Molecular Weight | 663.89 |
Formula | C33H49N3O7S2 |
CAS No. | 159989-65-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 93 mg/mL (140.1 mM)
Ethanol: 93 mg/mL (140.1 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Nelfinavir Mesylate 159989-65-8 Microbiology/Virology Proteases/Proteasome HIV Protease AG-1343 proliferation Viracept Nelfin HIV protease Nelfinavir AG1343 AG 1343 Mesylate cells infection Human immunodeficiency virus multiple inhibit phosphorylation AG-1343 Mesylate AG 1343 AG1343 Mesylate Inhibitor production myeloma inhibitor