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7-Ethoxyresorufin

Catalog No. T21507   CAS 5725-91-7
Synonyms: Resorufin ethyl ether

7-Ethoxyresorufin (Resorufin ethyl ether) (7-ER) is a fluorometric substrate for and competitive inhibitor of cytochrome P450, especially CYP1A1.

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7-Ethoxyresorufin Chemical Structure
7-Ethoxyresorufin, CAS 5725-91-7
Pack Size Availability Price/USD Quantity
1 mg In stock $ 30.00
2 mg In stock $ 38.00
5 mg In stock $ 61.00
10 mg In stock $ 101.00
25 mg In stock $ 206.00
50 mg In stock $ 369.00
1 mL * 10 mM (in DMSO) In stock $ 65.00
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Purity: 99.35%
Purity: 99.09%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description 7-Ethoxyresorufin (Resorufin ethyl ether) (7-ER) is a fluorometric substrate for and competitive inhibitor of cytochrome P450, especially CYP1A1.
In vivo 7-ER inhibited responses to NO and nitrergic nerve stimulation through generation of superoxide radicals. A 7-ER sensitive P450 system may be involved in the bioactivation of GTN and SNP in rat aortic rings, but not in rabbit aorta or rat anococcygeus muscles.
Synonyms Resorufin ethyl ether
Molecular Weight 241.24
Formula C14H11NO3
CAS No. 5725-91-7

Storage

keep away from direct sunlight

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMF: 1.92 mg/mL (8 mM)

TargetMolReferences and Literature

1. C G Li, et al. Inhibition of NO-medicate responses by 7-ethoxyresorufin, a substrate and competitive inhibitor of cytochrome P450. Br J Pharmacol. 1996 May;118(1):57-62. 2. Thomas K H Chang, et al. Enzymatic analysis of cDNA-expressed human CYP1A1, CYP1A2, and CYP1B1 with 7-ethoxyresorufin as substrate. Methods Mol Biol. 2006;320:85-90.

Related compound libraries

This product is contained In the following compound libraries:
Inhibitor Library Immunology/Inflammation Compound Library NO PAINS Compound Library Human Metabolite Library Anti-Cancer Compound Library Bioactive Compound Library Anti-Metabolism Disease Compound Library Metabolism Compound Library Bioactive Compounds Library Max Anti-Aging Compound Library

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Keywords

7-Ethoxyresorufin 5725-91-7 Immunology/Inflammation Metabolism P450 NO Synthase Nitric oxide synthases Cytochrome P450 CYP1A1 Resorufin ethyl ether 7 Ethoxyresorufin inhibit 7Ethoxyresorufin Inhibitor substrate CYPs Fluorometric NOS inhibitor

 

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