ventricular — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2712	Nifekalant hydrochloride		Potassium Channel
	Nifekalant hydrochloride is an IKr potassium channel blocker with an IC50 of 10 µM. It is a Class III antiarrhythmic compound and can be used in the study of tachyarrhythmias.		Potassium Channel
T15286	Flindokalner	BMS-204352	Potassium Channel
	Flindokalner (BMS-204352) is a potassium channel modulator and a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is a large conductance calcium-activated K channel (BKca) p...		Potassium Channel
T4550	Ajmaline	Cardiorythmine,Raugalline,Tachmalin,(+)-Ajmaline	Sodium Channel
	Ajmaline (Cardiorythmine) is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or ventricular tachycardia. Ajmaline inhibits cardiac Kv1.5 and...		Sodium Channel
T1498	Indapamide	Veroxil,Noranat,Tertensif	Potassium Channel
	Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.		Potassium Channel
T1496	Amiodarone hydrochloride	Amiodar,Amiodarone HCl,Nexterone	Potassium Channel , Adrenergic Receptor , Autophagy
	Amiodarone hydrochloride (Amiodarone HCl) is an antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM C...		Potassium Channel , Adrenergic Receptor , Autophagy
T20843	Aplodan	Nergize,Creatinolfosfate,creatinol-O-phosphate,Creatinolfosfate, Creatinol Phosphate	Others
	Aplodan (creatinol-O-phosphate) exhibits antiischemic and antiarrhythmic capacity and protective action on the cell membrane. Aplodan can be used in research on the ischemic heart or ischemic heart disease with persisten...		Others
T1320	Disopyramide	Triombrin,Hypaque sodium,amidotrizoate sodium	Potassium Channel , Sodium Channel , AChR
	Disopyramide (Triombrin) is a class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the h...		Potassium Channel , Sodium Channel , AChR
T5573	Coenzyme Q9	Ubiquinone Q9,Ubiquinone 9,CoQ9	Apoptosis , Endogenous Metabolite
	Coenzyme Q9 (Ubiquinone 9) (CoQ9) is a normal constituent of human plasma. CoQ9 in human plasma may originate as a product of incomplete CoQ10 biosynthesis or from the diet.		Apoptosis , Endogenous Metabolite
T1101	Minocycline hydrochloride	Minocycline HCl	HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
	Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochlor...		HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
T10634	Bunaftide	Bunaphtide,Meregon,Bunaftine	Others
	Bunaftide (Bunaphtid) has antiarrhythmic effects and inhibits aconitine-induced ventricular tachycardia.		Others
T7827	Glycyrrhizinic acid, potassium salt		Others
	Glycyrrhizinic acid, potassium salt can reduce ventricular arrhythmias caused by veratrol		Others
T68107	Moxaprindine
	Moxaprindine is a promising antiarrhythmic compound for the treatment of ventricular arrhythmias.
T3S0629	Delsoline	Belsoline	Others
	1. Delsoline (Belsoline) has hypotensive effects.2. Delsoline is not only effective in preventing ventricular fibrillation and arrythmia, but can raise the intebsity of the threthold of electrical shocks to cause ventric...		Others
T7386	Bretylium tosylate		Others
	Bretylium tosylate is an inhibitor of the presynaptic release of vasoconstrictor neurotransmitters, a available antiarrhythmic drug for ventricular arrhythmias.		Others
T28895	T-0509	T 0509,T0509	Adrenergic Receptor
	T-0509 is a selective beta 1 receptor agonist that increases inotropy in canine ventricular muscle and selectively down-regulates rat cardiac beta 1-adrenoceptors.		Adrenergic Receptor
T5S1099	Liensinine		Apoptosis , Mitophagy , Others , Autophagy
	1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.		Apoptosis , Mitophagy , Others , Autophagy
T6955	Propafenone hydrochloride	Propafenone HCl,Arythmol,SA-79 (hydrochloride),Rytmonorm,Rythmol	Sodium Channel
	Propafenone hydrochloride (Arythmol8) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias.		Sodium Channel
T8581	Flecainide hydrochloride		Others
	Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.		Others
T68123	Oxodipine		Calcium Channel
	Oxodipine, a dihydropyridine-type calcium antagonist , inhibited KCl-induced aortic contraction in rabbits and reduced cardiac force in less potent rat ventricular test-paper contractions. In rat cultured neonatal ventri...		Calcium Channel
T5968	DL-Homocysteine thiolactone hydrochloride	DL-Homocysteinethiolactone hydrochloride	Endogenous Metabolite
	DL-Homocysteine thiolactone hydrochloride (DL-Homocysteinethiolactone hydrochloride) is a cysteine derivative that binds to and induces conformational changes in various plasma proteins, slowing coagulation and inducing ...		Endogenous Metabolite