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20

Compounds

Cat No. Product Name Synonyms Targets
T9111 8-Azaadenosine Adenosine deaminase
8-Azaadenosine, a powerful ADAR1 (ADAR1) and A-to-I editing inhibitor, effectively blocks RNA editing and suppresses proliferation, 3D growth, invasion, and migration in thyroid cancer cells.
T12073 ML-109 TSH Receptor
ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM)
T5360 Eprotirome KB2115 Thyroid hormone receptor(THR)
Eprotirome (KB2115), a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.
T2282 RPI-1 Others , Phospholipase , c-Met/HGFR , c-RET
RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor.
T8843 APS6-45 MAPK , Ras
APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.
T1604 Tiratricol 3,3',5-Triiodothyroacetic acid Thyroid hormone receptor(THR)
Tiratricol (3,3',5-Triiodothyroacetic acid) is a metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of A...
T40548 NH-3 Thyroid hormone receptor(THR)
NH-3 is a potent orally active thyroid hormone receptor (THR) antagonist which exhibits reversible behavior, demonstrated by an IC 50 of 55 nM. Derived from the selective thyromi-metic GC-1, NH-3 effectively inhibits the...
T12192 NCGC00229600 Others , TSH Receptor
NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies.
T15012 Crolibulin EPC2407 Microtubule Associated
Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization.
T3595 Resmetirom VIA-3196,MGL3196 Thyroid hormone receptor(THR)
Resmetirom (VIA-3196) is a highly selective thyroid hormone receptor β (THR-β) agonist.
T13072 Taltirelin acetate TA-0910 acetate Thyroid hormone receptor(THR)
Taltirelin acetate (TA-0910 acetate) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release)).
T5383 D3-βArr NCGC00379308 TSH Receptor
D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.
T5313 Sobetirome IACS-010759,QRX-431 Thyroid hormone receptor(THR)
Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).
T1669 Liothyronine sodium 3,3',5-Triiodo-L-thyronine sodium,Triostat,T3 Sodium salt,Sodium L-3,3',5-triiodothyronine,Cytomel Thyroid hormone receptor(THR)
Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine s...
T13492 3,5-Diiodothyropropionic acid C082182,Ditpa cpd Thyroid hormone receptor(THR)
3,5-Diiodothyropropionic acid (C082182) is a thyroid hormone analog. It induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (Ka: 2.40/M and 4.06/M for TRα1 and TRβ1).
TP1022 Protirelin Acetate TSH-RF Acetate,TRH Acetate,TRF Acetate Thyroid hormone receptor(THR) , Endogenous Metabolite
Protirelin Acetate (TRH Acetate) is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary.
T7578 REVERSE T3 3,3',5'-triiodo-L-thyronine Thyroid hormone receptor(THR)
Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.
T1653 Liothyronine Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,Triiodothyronine,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine Thyroid hormone receptor(THR) , Endogenous Metabolite
Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.
T5568 H-Tyr(3-I)-OH 3-Iodo-L-tyrosine Endogenous Metabolite
H-Tyr(3-I)-OH (3-Iodo-L-tyrosine) is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones
T0864 L-Thyroxine Levothyroxine,NSC 36397,T4 Thyroid hormone receptor(THR) , Endogenous Metabolite
L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in...

Compounds

8-Azaadenosine
T9111
Synonym:
Target: Adenosine deaminase
ML-109
T12073
Synonym:
Target: TSH Receptor
Eprotirome
T5360
Synonym: KB2115
Target: Thyroid hormone receptor(THR)
RPI-1
T2282
Synonym:
Target: Others, Phospholipase, c-Met/HGFR, c-RET
APS6-45
T8843
Synonym:
Target: MAPK, Ras
Tiratricol
T1604
Synonym: 3,3',5-Triiodothyroacetic acid
Target: Thyroid hormone receptor(THR)
NH-3
T40548
Synonym:
Target: Thyroid hormone receptor(THR)
NCGC00229600
T12192
Synonym:
Target: Others, TSH Receptor
Crolibulin
T15012
Synonym: EPC2407
Target: Microtubule Associated
Resmetirom
T3595
Synonym: VIA-3196,MGL3196
Target: Thyroid hormone receptor(THR)
Taltirelin acetate
T13072
Synonym: TA-0910 acetate
Target: Thyroid hormone receptor(THR)
D3-βArr
T5383
Synonym: NCGC00379308
Target: TSH Receptor
Sobetirome
T5313
Synonym: IACS-010759,QRX-431
Target: Thyroid hormone receptor(THR)
Liothyronine sodium
T1669
Synonym: 3,3',5-Triiodo-L-thyronine sodium,Triostat,T3 Sodium salt,Sodium L-3,3',5-triiodothyronine,Cytomel
Target: Thyroid hormone receptor(THR)
3,5-Diiodothyropropionic acid
T13492
Synonym: C082182,Ditpa cpd
Target: Thyroid hormone receptor(THR)
Protirelin Acetate
TP1022
Synonym: TSH-RF Acetate,TRH Acetate,TRF Acetate
Target: Thyroid hormone receptor(THR), Endogenous Metabolite
REVERSE T3
T7578
Synonym: 3,3',5'-triiodo-L-thyronine
Target: Thyroid hormone receptor(THR)
Liothyronine
T1653
Synonym: Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,Triiodothyronine,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine
Target: Thyroid hormone receptor(THR), Endogenous Metabolite
H-Tyr(3-I)-OH
T5568
Synonym: 3-Iodo-L-tyrosine
Target: Endogenous Metabolite
L-Thyroxine
T0864
Synonym: Levothyroxine,NSC 36397,T4
Target: Thyroid hormone receptor(THR), Endogenous Metabolite
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TargetMol