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Endocrinology/Hormones Thyroid hormone receptor(THR) L-Thyroxine

L-Thyroxine

Catalog No. T0864   CAS 51-48-9
Synonyms: T4, Levothyroxine, NSC 36397

Levothyroxine is the major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.

L-Thyroxine, CAS 51-48-9
Pack Size Availability Price/USD Quantity
25 mg In stock 20.00
50 mg In stock 30.00
100 mg In stock 40.00
200 mg In stock 50.00
500 mg In stock 59.00
1 g In stock 75.00
1 mL * 10 mM (in DMSO) In stock 64.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Levothyroxine is the major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
Targets&IC50 Thyroid hormone,  
Synonyms T4 , Levothyroxine , NSC 36397
Purity 98.21%
Molecular Weight 776.87
Formula C15H11I4NO4
CAS No. 51-48-9

Storage

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

Solubility Information

DMSO: 93 mg/mL (119.7 mM)

Ethanol: <1 mg/mL

Water: <1 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Marazuela M, et al. Thyroid. 2008 Oct; 18(10):1119-23.

Related compound libraries

This product is contained In the following compound libraries:
Approved Drug Library Bioactive Compound Library Inhibitor Library Natural Compound Library for HTS Endocrinology-Hormones Library Human Endogenous Metabolite Compound Library FDA-approved Drug Library

Related Products

Related compounds with same targets
Taltirelin acetate KAT681 L-Thyroxine sodium salt pentahydrate CO23 Levothyroxine sodium MGL3196 Liothyronine sodium O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine

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