Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Protirelin Acetate is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary.
Description | Protirelin Acetate is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary. |
In vivo | Protirelin (TRH) is an evolutionarily ancient neuropeptide, having its origin before the divergence of protostomes and deuterostomes that may ancestrally have been involved in the control of postembryonic growth and reproduction[1]. The effect of the thyrotropin-releasing hormone (Protirelin, TRH), one of the hypothalamic releasing hormones, on body temperature is investigated in the rat. Protirelin, in doses of 1, 5, 10 and 20 mg/kg, is injected intraperitoneally to male Wistar rats weighing 200-250 g. Protirelin causes a temporary rise in body temperature dose-dependently. The thyroidectomized rats injected 20 mg/kg of Protirelin which induces a significant hyperthermia in the sham-operated animals, fail to show a rise in body temperature. The present results suggest that a release of thyroid hormone might participate in the hyperthermic action of Protirelin[2]. |
Synonyms | 醋酸普罗瑞林, TSH-RF Acetate, TRH Acetate, TRF Acetate |
Molecular Weight | 904.936 |
Formula | C38H56N12O14 |
CAS No. | 120876-23-5 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
H2O: 50 mg/mL (110.51 mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Protirelin Acetate 120876-23-5 代谢 内分泌与激素 Endogenous Metabolite Thyroid hormone receptor(THR) TRH Acetate inhibit THR TRF Acetate Protirelin TRH Thyroid Hormone Receptor TSH-RF Acetate Inhibitor inhibitor