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Protirelin Acetate
😃Good
Catalog No. TP1022Cas No. 120876-23-5
Alias TSH-RF Acetate, TRH Acetate, TRF Acetate
Protirelin Acetate (TRH Acetate) is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary.
Protirelin Acetate
😃Good
Purity: 96.17%
Catalog No. TP1022Alias TSH-RF Acetate, TRH Acetate, TRF AcetateCas No. 120876-23-5
Protirelin Acetate (TRH Acetate) is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $40 | In Stock | |
| 10 mg | $67 | In Stock | |
| 25 mg | $81 | In Stock | |
| 50 mg | $97 | In Stock | |
| 100 mg | $157 | In Stock | |
| 500 mg | $392 | Backorder |
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Purity:96.17%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Protirelin Acetate (TRH Acetate) is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary. |
| In vivo | Protirelin (TRH) is an ancient neuropeptide that emerged before the divergence of protostomes and deuterostomes, possibly playing a role in regulating postembryonic growth and reproduction[1]. This study explores Protirelin's impact on body temperature, administering intraperitoneal doses of 1, 5, 10, and 20 mg/kg to male Wistar rats weighing 200-250 g. The findings reveal a dose-dependent, temporary increase in body temperature following Protirelin administration. However, thyroidectomized rats injected with 20 mg/kg of Protirelin did not experience a temperature rise, unlike their sham-operated counterparts. These observations indicate that thyroid hormone release may contribute to Protirelin's hyperthermic effect[2]. |
| Alias | TSH-RF Acetate, TRH Acetate, TRF Acetate |
| Molecular Weight | 452.46 |
| Formula | C16H22N6O4.3/2C2H4O2 |
| Cas No. | 120876-23-5 |
| Smiles | CC(=O)O.CC(=O)O.CC(=O)O.C1CC(N(C1)C(=O)C(CC2=CN=CN2)NC(=O)C3CCC(=O)N3)C(=O)N.C1CC(N(C1)C(=O)C(CC2=CN=CN2)NC(=O)C3CCC(=O)N3)C(=O)N |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 50 mg/mL (110.51 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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