sympathetic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0287	Hexamethonium Bromide	Gangliostat,Simpatoblock,Hexamethonium Dibromide	Apoptosis , Dopamine Receptor , AChR
	Hexamethonium Bromide (Hexamethonium Dibromide), a specific antagonist of neuronal-type nicotinic AChR in ganglia, is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier.		Apoptosis , Dopamine Receptor , AChR
T28540	Ripisartan	UP 269-6,UP-2696,UP 2696,UP-269-6,UP269-6	RAAS
	Ripisartan (UP-269-6) is a potent and specific angiotensin II receptor antagonist that inhibits angiotensin II-mediated sympathetic tachycardia responses.		RAAS
T22963	McN-A 343		AChR
	McN-A 343 is a selective M1 muscarinic agonist known for its ability to stimulate muscarinic transmission in sympathetic ganglia. It has been found to effectively reduce inflammation and oxidative stress in experimental ...		AChR
T1287	Synephrine	Oxedrine	Endogenous Metabolite , Adrenergic Receptor
	Synephrine (Oxedrine) is sympathetic alpha-adrenergic agonist used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma.		Endogenous Metabolite , Adrenergic Receptor
T6751	Acetylcholine iodide	Acetylcolina	Others
	Acetylcholine iodide (Acetylcolina) is a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the cent...		Others
T68095	Losulazine		Dopamine Receptor , Norepinephrine
	Losulazine is a peripheral sympathetic antihypertensive compound that can be taken orally. Losulazine causes relatively modest, transient depletion of dopamine and norepinephrine in brain regions protected by the blood-b...		Dopamine Receptor , Norepinephrine
T12160	N6-Cyclohexyladenosine	CHA	Adenosine Receptor
	N6-Cyclohexyladenosine (CHA) is a selective agonist of A1 receptor with EC50 of 8.2 Nm. N6-Cyclohexyladenosine exerts anticonvulsant effects and protects against neuronal death. CHA was also found to inhibit the pressor ...		Adenosine Receptor
T5954	Methyldopa hydrate	Alpha-Methyldopa Sesquihydrate,L-(-)-α-Methyldopa hydrate,MK-351 hydrate,Methyldopa Sesquihydrate	Dopamine Receptor , Adrenergic Receptor
	Methyldopa hydrate (MK-351 hydrate) is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sympathetic nervous system, decreases production of dopamine, ...		Dopamine Receptor , Adrenergic Receptor
T7040	Angiotensin II human	DRVYIHPF,Angiotensin II,Hypertensin II,Ang II	Apoptosis , RAAS
	Angiotensin II human (Ang II) is a biologically active peptide, a vasoconstrictor. Angiotensin II interacts with AT1R and AT2R to regulate blood pressure, stimulate sympathetic nerves, and increase aldosterone biosynthes...		Apoptosis , RAAS
T20344	Acetylcholine bromide		Others
	Acetylcholine bromide is the bromide salt of acetylcholine. It is an neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, a...		Others
TP1618L	PACAP-38 (31-38), human, mouse, rat acetate	PACAP-38 (31-38), human, mouse, rat acetate(138764-85-9 Free base)	PACAP
	PACAP-38 (31-38), human, mouse, rat acetate is an activator of PAC1 receptor. PACAP-38 (31-38), human, mouse, rat acetate demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY an...		PACAP
T3S2259	Methyl eugenol	4-allylveratrole,eugenyl methyl ether,O-methyleugenol,Eugenol Methyl ether	GABA Receptor
	1. Methyl eugenol (4-allylveratrole) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcinogenic potential of ME, the need to check its...		GABA Receptor
T24603	PD-34799-SA	PD 34799-SA,PD34799-SA
	PD-34799-SA is an effective inhibitor of vasoconstrictor responses to sympathetic nerve stimulation.
T29548	Acetabuton	Aceperone
	Acetabuton is an alpha-adrenergic blocker and a hemodynamic and sympathetic drug.
TP1618	PACAP-38 (31-38), human, mouse, rat
	PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production.
T9097L	Guanadrel Sulfate	CL 1388R,U 28288D,CHEBI:5556,Hylorel,Hyloride
	Guanadrel Sulfate is a postganglionic adrenergic blocking agent. The uptake of guanadrel and storage in sympathetic neurons occurs via the norepinephrine pump or transporter.
T24032	Ephedrine levulinate	L-Ephedrine levulinate
	Ephedrine levulinate is an alkaloid. Ephedrine acts as an agonist at alpha- and beta-adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons.
T68634	Wy 26392
	Wy 26392 is an alpha 2 adrenoceptors antagonist that increase central sympathetic tone and blood pressure in low doses.
T68190	Carmoxirole (free base)
	Carmoxirole (free base) is a dopamine D2 receptor agonist with limited central activity that modulates sympathetic activation and subsequently reduces pre-load and afterload in animals. It was shown, that carmoxirole ind...
T68397	Xamoterol fumarate
	Xamoterol fumarate is a selective beta-1-adrenergic partial agonist. Because it is a partial agonist, it acts as an agonist when sympathetic activity is low and as an antagonist when sympathetic activity is high. It redu...