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Cat No. | Product Name | Synonyms | Targets |
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T4276L | Hydroxyfasudil | Hydroxy-Fasudil,HA-1100 | ROCK , PKA |
Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively). | |||
T3480 | Sudoterb free base | Sudoterb | ATPase |
Sudoterb free base (Sudoterb) , also known as LL3858, is an anti-tubercular drug candidate. | |||
T3060 | Fasudil hydrochloride | Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877 | ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy |
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively. | |||
T10358 | Netarsudil Dihydrochloride | AR-13324 Dihydrochloride | ROCK |
Netarsudil Dihydrochloride (AR-13324 Dihydrochloride) is an inhibitor of Rho-associated protein kinase (ROCK) and norepinephrine transporter (NET) with effective in intraocular pressure (IOP) reduction. | |||
T4276 | Hydroxyfasudil Hydrochloride | Hydroxyfasudil (HA-1100) HCl,HA 1100 hydrochloride | ROCK |
Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM). | |||
TQ0319 | Ripasudil | K-115,Ripasudil hydrochloride dihydrate | ROCK |
Ripasudil (Ripasudil hydrochloride dihydrate) (K-115) hydrochloride dihydrate is a specific ROCK inhibitor (IC50s: 51/19 nM for ROCK1/ROCK2). | |||
T1606 | Fasudil | HA-1077,AT877 | ROCK , Serine/threonin kinase , Calcium Channel , PKA , PKC , Autophagy |
Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK. | |||
T69665 | Zelasudil | RXC007 | ROCK |
Zelasudil (RXC007) is a Rho-related (ROCK) kinase inhibitor for the study of idiopathic pulmonary fibrosis and inflammation. | |||
T38654 | Cotosudil | ROCK | |
Cotosudil is a ROCK kinase inhibitor with antihypertensive activity and is used to treat or prevent diseases or conditions caused by cataracts, cardiovascular or neurodegenerative diseases or nerve damage. | |||
T5612 | Sudan III | Solvent Red 23,Tetrazobenzene-β-naphthol,111440 Red,Sudan Red III | Others |
Sudan III (Solvent Red 23) is a solvent dye used to color nonpolar substances. | |||
T16950 | Sudoxicam | 4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide | COX |
Sudoxicam (4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) is a reversible antagonist of COX with anti-inflammatory, anti-edema, and antipyretic properties. | |||
T60924 | Verosudil | AR-12286 | ROCK |
Verosudil (AR-12286) is a highly potent Rho kinase (ROCK) inhibitor with a Ki of 2 and 2 nM against ROCK1 and ROCK2, respectively. AR-12286 reverses steroid-induced intraocular pressure in mice by decreasing intraocular ... | |||
T6867 | Belumosudil | KD025,Rezurock,ROCK inhibitor,SLx-2119 | ROCK |
Belumosudil (Rezurock) is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM). | |||
TN2363 | Sudan II | Solvent Orange 7,Sudan Red II | Others |
Sudan II (Solvent Orange 7) is a dyes. | |||
T10358L2 | Netarsudil mesylate | AR-13324 (mesylate) | Others |
Netarsudil mesylate is an inhibitor of Rho-associated protein kinase (ROCK) and norepinephrine transporter (NET) with effective in intraocular pressure (IOP) reduction. | |||
T76783 | Moxetumomab pasudotox | ||
Moxetumomab Pasudotox (CAT 8015) is an anti-CD22 immunotoxin comprising an anti-CD22 Fv and Pseudomonas exotoxin, targeting the CD22 cell surface receptor present on various malignant B-cells. This compound is applicable... | |||
T71119 | Netarsudil free base | ||
Netarsudil, also known as AR-11324, is a Rho-associated protein kinase inhibitor. Netarsudil is potential useful for treating glaucoma and/or reducing intraocular pressure. Netarsudil Increases Outflow Facility in Hum... | |||
T3480L | Sudoterb HCl | LL3858,LL-3858,Sudoterb dihydrchloride,LL 3858 | |
Sudoterb has anti-tubercular activity. | |||
T70108 | Fasudil hydrochloride hydrate | ||
Fasudil hydrochloride hydrate is an HCl salt of Fasudil -- a Rho-kinase (ROCK) inhibitor that has been shown to be effective in hindering the development of mature Cerebral Cavernous Malformation (CCM) lesions as well as... | |||
T77189 | Sudubrilimab | ||
Sudubrilimab (HS636), an Ig G1-kappa monoclonal antibody targeting PDL1, is engineered with a TGF-β1 receptor II ectodomain (TGFBR2-ECD) fused to its C-terminus. This design enables Sudubrilimab to simultaneously inhibit... | |||
T39555 | Belumosudil mesylate | SLx-2119mesylate,KD025 mesylate | |
Belumosudil mesylate (KD025 mesylate) is a compound that selectively inhibits ROCK2, demonstrating IC50 values of 105 nM for ROCK2 and 24 μM for ROCK1. It possesses anti-fibrotic properties. | |||
T76903 | Alvircept sudotox | ||
Alvircept sudotox, a recombinant CD4 fused with exotoxin A from Pneumonas aeruginosa, is utilized in HIV infection research [1]. | |||
TP2371 | Asudemotide | Glu-tyr-tyr-glu-leu-phe-val-asn-ile | |
Asudemotide is a bioactive chemical. | |||
T77211 | Sudan I-d | ||
Sudan I-d 5, the deuterated variant of Sudan I, is a diazo-conjugate red dye utilized in oils, solvents, or polishes as an additive. Notably, it hampers the growth of bacterial strains Clostridium perfringens and L. rham... | |||
T71106 | Cotosudil 2HCl | ||
Cotosudil 2HCl is the salt form of Cotosudil Free Base, a Rho-associated (ROCK) kinase inhibitor. | |||
T62608 | Sovesudil hydrochloride | ||
Sovesudil (PHP-201) hydrochloride is a potent, ATP-competitive, locally acting Rho kinase (ROCK) inhibitor that acts on ROCK I (IC50: 3.7 nM) and ROCK II (IC50: 2.3 nM). Sovesudil hydrochloride is capable of lowering IOP... | |||
T64582 | Fasudil hydrochloride semihydrate | ||
Fasudil hydrochloride semihydrate is a useful organic compound for research related to life sciences and the catalog number is T64582. | |||
T124974 | Natsudaidain | ||
Natsudaidain is a useful organic compound for research related to life sciences and the catalog number is T124974. | |||
T125643 | 7-Methylsudachitin | ||
7-Methylsudachitin is a useful organic compound for research related to life sciences. The catalog number is T125643 and the CAS number is 16520-78-8. | |||
T70735 | Verosudil hydrochloride | ||
Verosudil, also known as AR-12286, is a potent and selective Rho kinase inhibitor. AR-12286 was well tolerated and provided statistically significant reduction in IOP (intraocular pressure) in patients with XFS (exfolia... | |||
T7492 | Ripasudil free base | K-115 (free base) | ROCK , Antibacterial |
Ripasudil free base (K-115 (free base)) is a selective and potent ROCK inhibitor, is a novel and potent antiglaucoma agent. | |||
T62036 | Sovesudil | ||
Sovesudil (PHP-201) is a potent, ATP-competitive, locally acting Rho kinase (ROCK) inhibitor. Sovesudil shows IC50 s of 3.7 and 2.3 nM for ROCK-I and ROCK-II, respectively. Sovesudil can lower intraocular pressure (IOP) ... | |||
T74418 | Sudocetaxel | ||
Sudocetaxel is a compound that serves as a microtubule depolymerization inhibitor, specifically designed for the pH-sensitive delivery of docetaxel. | |||
T61382 | Fasudil dihydrochloride | ||
Fasudil dihydrochloride, also known as HA-1077 and AT877, is a nonspecific inhibitor of RhoA/ROCK. It exhibits inhibitory effects on protein kinases, including ROCK1 with a Ki value of 0.33 μM, as well as ROCK2, PKA, PKC... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN2364 | Sudan IV | Solvent Red 24,C.I. 26105 | Others |
Sudan IV (Solvent Red 24) is a lysochrome (fat-soluble dye) diazo dye used for the staining of triglycerides,lipids and lipoproteins on frozen paraffin sections. | |||
TN2362 | Sudan I | Solvent Yellow 14 | Others , Antibacterial |
Sudan I (Solvent Yellow 14) is an organic compound, typically classified as an azo dye. | |||
T8284 | Sudan Orange G | Others | |
SUDAN ORANGE G is a natural product. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00524 | ATP-dependent DNA helicase dda Protein, Enterobacteria phage T4, Recombinant (His) | Enterobacteria phage T4 | E. coli |
DNA helicase that stimulates viral DNA replication and recombination. Plays a role in T4 DNA replication initiation by selecting and activating DNA origins. Acts by dissociating and reassociating with the DNA molecule be... | |||
TMPY-00238 | Ebola virus EBOV (subtype Sudan, strain Gulu) GP1/Glycoprotein Protein (His) | EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Sudan, strain Gulu) GP1/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.5 kDa and the accession number is A0A0E3KN50. | |||
TMPY-00281 | Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His & MBP) | EBOV | E. coli |
Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His & MBP) is expressed in E. coli expression system with His and MBP tag. The predicted molecular weight is 79.1 kDa and the accession numb... | |||
TMPY-00235 | Ebola virus EBOV (subtype Sudan, strain Gulu) GP/Glycoprotein Protein (His) | EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Sudan, strain Gulu) GP/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.9 kDa and the accession number is A0A0E3KN50. | |||
TMPY-04159 | Ebola virus EBOV (Subtype Sudan, strain Gulu) Glycoprotein/GP Protein (aa 1-637, His) | EBOV | Baculovirus Insect Cells |
Ebola virus EBOV (Subtype Sudan, strain Gulu) Glycoprotein/GP Protein (aa 1-637, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 67.9 kDa and the accession number is A0A0E3KN... | |||
TMPY-00234 | Ebola virus EBOV (subtype Sudan, strain Gulu) GP-RBD/Glycoprotein Protein (hFc) | EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Sudan, strain Gulu) GP-RBD/Glycoprotein Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 59 kDa and the accession number is A0A0E3KN50. | |||
TMPY-00308 | Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (His) | EBOV | E. coli |
Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 14.8 kDa and the accession number is A0A2U8KL52. | |||
TMPY-00216 | Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His) | EBOV | E. coli |
Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.5 kDa and the accession number is B0LPL6. | |||
TMPY-04526 | Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (aa 361-738, His) | EBOV | E. coli |
Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (aa 361-738, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 44.1 kDa and the accession number is A... | |||
TMPY-00199 | Ebola virus EBOV (Subtype Sudan, strain Gulu) Glycoprotein/GP1 (mucin domain deleted) Protein (aa 1-320, His) | EBOV | Baculovirus Insect Cells |
Ebola virus EBOV (Subtype Sudan, strain Gulu) Glycoprotein/GP1 (mucin domain deleted) Protein (aa 1-320, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 33.8 kDa and the acce... |