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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6043 | PF-3845 | FAAH , Autophagy | |
PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2. | |||
T7177 | Capsazepine | Apoptosis , TRP/TRPV Channel | |
Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM). Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel. It is ... | |||
T0030 | Bupivacaine hydrochloride | Vivacaine,Bupivacaine HCl | Sodium Channel |
Bupivacaine hydrochloride (Vivacaine) is a long-acting, amide-type local anesthetic. Bupivacaine hydrochloride reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the vol... | |||
T0802 | Procaine hydrochloride | Novocaine HCl,Procaine HCl | Histone Demethylase , 5-HT Receptor , DNA/RNA Synthesis , Sodium Channel , NMDAR , AChR |
Procaine hydrochloride (Novocaine HCl) is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodiumchannel... | |||
T3S0209 | Vincristine | ERK , p38 MAPK , NF-κB , Akt , JNK , mTOR | |
Vincristine binds to tubulin and inhibits the formation of microtubules, thereby inhibiting mitosis of the cancer cell. Vincristine can be used as a microtubule-destabilizing agent for research on the treatment of hemato... | |||
T2163 | Dihydrocapsaicin | CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide | Others , TRP/TRPV Channel |
Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an... | |||
T19363 | Hydroxyl-γ-isosanshool | Others | |
Hydroxyl-γ-isosanshool induces a numbing sensation. It is one of the major alkylamides in Z. bungeanum and Z. schinifolium oils. | |||
T35374L | (Ala13)-Apelin-13 acetate | Apelin receptor | |
(Ala13)-Apelin-13 acetate, an APJ antagonist, modulates CRF-induced enhanced colonic motility, visceral sensation, and gut barrier. | |||
TP1647 | β-Endorphin, equine | ||
Endorphin Beta is A substance produced in the brain, especially in the pituitary gland, Endorphin Beta blocks the sensation of pain. Endorphin Beta is produced in response to pain, exercise, and other forms of stress. En... |