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Search Results for " sensation "

9

Compounds

Cat No. Product Name Synonyms Targets
T6043 PF-3845 FAAH , Autophagy
PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.
T7177 Capsazepine Apoptosis , TRP/TRPV Channel
Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM). Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel. It is ...
T0030 Bupivacaine hydrochloride Vivacaine,Bupivacaine HCl Sodium Channel
Bupivacaine hydrochloride (Vivacaine) is a long-acting, amide-type local anesthetic. Bupivacaine hydrochloride reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the vol...
T0802 Procaine hydrochloride Novocaine HCl,Procaine HCl Histone Demethylase , 5-HT Receptor , DNA/RNA Synthesis , Sodium Channel , NMDAR , AChR
Procaine hydrochloride (Novocaine HCl) is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodiumchannel...
T3S0209 Vincristine ERK , p38 MAPK , NF-κB , Akt , JNK , mTOR
Vincristine binds to tubulin and inhibits the formation of microtubules, thereby inhibiting mitosis of the cancer cell. Vincristine can be used as a microtubule-destabilizing agent for research on the treatment of hemato...
T2163 Dihydrocapsaicin CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide Others , TRP/TRPV Channel
Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an...
T19363 Hydroxyl-​γ-​isosanshool Others
Hydroxyl-γ-isosanshool induces a numbing sensation. It is one of the major alkylamides in Z. bungeanum and Z. schinifolium oils.
T35374L (Ala13)-Apelin-13 acetate Apelin receptor
(Ala13)-Apelin-13 acetate, an APJ antagonist, modulates CRF-induced enhanced colonic motility, visceral sensation, and gut barrier.
TP1647 β-Endorphin, equine
Endorphin Beta is A substance produced in the brain, especially in the pituitary gland, Endorphin Beta blocks the sensation of pain. Endorphin Beta is produced in response to pain, exercise, and other forms of stress. En...
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