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20

Compounds

Cat No. Product Name Synonyms Targets
T76792 Sibrotuzumab BIBH 1,Anti-Human FAP Recombinant Antibody Others
Sibrotuzumab (BIBH 1) is a humanized IgG1 monoclonal antibody targeting Fibroblast Activating Protein (FAP).Sibrotuzumab is used in the study of colorectal cancer and non-small cell lung cancer.
T76830 Teneliximab Chi220,Anti-Human CD40 Recombinant Antibody,BMS 224819 TNF
Teneliximab (Chi220) is a chimeric monoclonal antibody and a tumor necrosis factor receptor superfamily member 5 (CD40) inhibitor that blocks CD40-CD40L interactions.Teneliximab exerts partial agonist activity through CD...
T80744 Zanolimumab Anti-Human CD4 Recombinant Antibody
Zanolimumab (Anti-Human CD4 Recombinant Antibody) is a fully human monoclonal antibody that targets the CD4 molecule and effectively inhibits T-cell receptor (TCR) signal transduction. It is used in the research of rheum...
T78288 Inclacumab Anti-Human selectin P Recombinant Antibody
Inclacumab, a humanized monoclonal IgG4 antibody (Anti-Human Selectin P Recombinant Antibody), specifically binds to P-selectin with a dissociation constant (Kd) of 9.9 nM. It effectively prevents the interaction between...
T78289 Ligelizumab QGE 031,Anti-IGHE Recombinant Antibody
Ligelizumab (QGE 031), a high-affinity humanized monoclonal anti-IgE antibody, is utilized in the research of chronic spontaneous urticaria [1].
T81655 Nonacog alfa BAX326,Coagulation Factor IX [Recombinant]
Nonacog alfa (BAX326), a recombinant human factor IX, is utilized in the study of hemophilia B [1].
T5183 AUT1 Potassium Channel
AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9 uM for Kv3.1b and Kv3.2a).
T82858 Bleselumab ASKP 1240,Anti-Human CD40 Recombinant Antibody
Bleselumab (ASKP 1240), a human anti-CD40 monoclonal antibody (mAb), exhibits high-affinity binding to CD40 (Kd: 0.24 nM) and hinders immune responses by impeding the CD40-CD40L interaction, thereby preventing organ tran...
T81259 Rontalizumab RhuMab IFNalpha,Anti-Human IFN alpha Recombinant Antibody
Rontalizumab, a humanized IgG1 monoclonal antibody, targets IFN-α and is utilized in research on systemic lupus erythematosus[1].
T81050 Talizumab TNX 901,Anti-Human IgE Fc Recombinant Antibody
Talizumab (TNX 901), a humanized IgG1 monoclonal antibody, targets IgE [1].
T76202 Recombinant Proteinase K
Recombinant Proteinase K, a serine protease, targets the carboxy-terminal peptide bonds of both aliphatic and aromatic amino acids. It is utilized to digest proteins and eradicate contamination in nucleic acid preparatio...
T14505 BAY-524 Others
BAY-524 is an inhibitor of Bub1(IC50 = 450 nM.human Bub1 in the presence of 2 mM ATP).
T9276 SBC-115337 Others , Serine/threonin kinase
SBC-115337 is a PCSK9 inhibitor.
T2044 Varespladib LY315920 Phospholipase
Varespladib (LY315920), a specific and effective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor(IC50=7 nM), has been investigated for the treatment and prevention of sickle cell disease, vaso-occlusiv...
T7369L Gemigliptin Tartrate(911637-19-9 free base) LC15-0444 tartrate Proteasome , DPP-4
Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibit...
T18914 AkaLumine hydrochloride AkaLumine hydrochloride (1176235-08-7 free base),AkaLumine hydrochloride
AkaLumine hydrochloride is a fluorescein analog with a Km value of 2.06 μM for recombinant fluorescent protein.
T23518 VUF 5574 Adenosine Receptor
VUF 5574 is a selective antagonist of adenosine A3 receptor with a Ki of 4.03 nM for the recombinant human receptor.
T4231 MD2-IN-1 TLR
MD2-IN-1 is a Myeloid differentiation protein 2 (MD2) inhibitor with a KD of 189  μM for the recombinant human MD2 (rhMD2).
T2000 AM095 LPA Receptor , LPL Receptor
AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.
T14778 BRD6989 IL Receptor , CDK , Interleukin
BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes. BRD6989 selectively binds a complex...
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