prokinetic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0082	Domperidone	R33812	Dopamine Receptor
	Domperidone (R33812)(Motilium) is a dopamine blocker and an antidopaminergic reagent. It blocks the action of. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger z...		Dopamine Receptor
T1552	Itopride hydrochloride	HSR803,Ganaton	Dopamine Receptor , AChE
	Itopride hydrochloride (Ganaton) is an AChE and D2DR inhibitor.		Dopamine Receptor , AChE
T1291	Cisapride	Prepulsid,R 51619,Pridesia,Kaudalit,(±)-Cisaprid,Kinestase	Potassium Channel , 5-HT Receptor , HER
	Cisapride (R 51619) is a serotonin type 4 (5-HT4) receptor agonists are potent prokinetic agents that act on serotonin receptors in the intestine and promote intestinal peristalsis, increase gastric emptying and decrease...		Potassium Channel , 5-HT Receptor , HER
T76655	Prokineticin 2 Isoform 2 (human)
	Prokineticin 2 Isoform 2 (human), a hypothalamic neuropeptide, regulates thermoregulation and energy metabolism while decreasing food intake in rodents. This isoform is implicated in the study of metabolic syndrome (MetS...
T13997	AU-224		Others
	AU-224 is an orally available benzamide derivative that is a potent gastrointestinal prokinetic.		Others
T28043L	Minesapride		5-HT Receptor
	Minesapride, a novel 5-hydroxytryptamine 4 (5-HT4) receptor partial agonist, is a potential gastrointestinal prokinetic agent for the treatment of irritable bowel syndrome with constipation.		5-HT Receptor
T1175	Bromopride	Bromoprida,Valopride,Artomey	Dopamine Receptor
	Bromopride (Valopride) is a dopamine antagonist with prokinetic properties closely related to metoclopramide, and is widely used as an antiemetic. It is not available in the United States or the United Kingdom.		Dopamine Receptor
T28934	Felcisetrag	TD 8954,TD8954,TD-8954	5-HT Receptor
	Felcisetrag (TD-8954) is a potent and selective orally active 5-HT4 agonist with gastrointestinal prokinetic properties.Felcisetrag shows high affinity for the human recombinant 5-HT4(c) (h5-HT4(c)) receptor with a pKi o...		5-HT Receptor
TN1922	Meranzin hydrate		ERK , Adrenergic Receptor
	Meranzin hydrate exhibits antidepressive and prokinetic-like effects through the regulation of the common mediator, the alpha 2-adrenoceptor , and α±-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors; it produ...		ERK , Adrenergic Receptor
T5S2360	Corydaline	Corydalin,(+)-Corydaline	P450 , Virus Protease , Opioid Receptor , AChE
	1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastr...		P450 , Virus Protease , Opioid Receptor , AChE
T2319	Acotiamide monohydrochloride trihydrate	Acotiamide hydrochloride,YM-443 HCl,Z-338 HCl	AChE
	Acotiamide monohydrochloride trihydrate (Z-338 HCl) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamid...		AChE
T17202	Ulimorelin	TZP-101	Others
	Ulimorelin is a ghrelin receptor agonist (EC50: 29 nM and a Ki of 16 nM). Ulimorelin is a prokinetic agent and causes vasorelaxation through competitive antagonist action at α1-adrenoceptors.		Others
T63819	Domperidone monomaleate
	Domperidone (R33812) monomaleate is a selective, orally active dopamine-2 receptor antagonist that affects the chemoreceptor trigger zone and motor function in the stomach and small intestine, and has antiemetic and prok...
T63785	Naronapride
	Naronapride (ATI-7505) is a potent agonist of the prokinetic 5-HT4receptor and can be used to study gastrointestinal disorders.
T69152	Bromopride hydrochloride
	Bromopride hydrochloride is the salt form of Bromopride, a dopamine D2 receptor blocker. Bromopride exerts is a gastrointestinal prokinetic exploited clinically for the management of motor disorders of the upper gastroin...
T76426	[Lys5,MeLeu9,Nle10]Neurokinin A(4-10)
	[Lys5,MeLeu9,Nle10]Neurokinin A(4-10) (LMN-NKA), a Neurokinin A analogue, serves as a selective and potent agonist for the NK2 receptor (NK2R). This compound exhibits prokinetic activity, making it a valuable tool for re...