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Acotiamide monohydrochloride trihydrate

Catalog No. T2319 CAS 773092-05-0

Synonyms: Acotiamide hydrochloride, YM-443 HCl, Z-338 HCl

Acotiamide monohydrochloride trihydrate (Z-338 HCl) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamide exerts its effect has yet to be fully elucidated, this agent appears to inhibit acetylcholinesterase (AchE), an enzyme responsible for the breakdown of acetylcholine (Ach). Increased Ach concentrations lead to an improvement of gastric emptying and GI motility and eventually to a reduction of dyspepsia symptoms.

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Acotiamide monohydrochloride trihydrate Chemical Structure

Acotiamide monohydrochloride trihydrate, CAS 773092-05-0

Pack Size	Availability	Price/USD
50 mg	In stock	$ 31.00
100 mg	In stock	$ 42.00
500 mg	In stock	$ 92.00
1 g	In stock	$ 133.00
1 mL * 10 mM (in DMSO)	In stock	$ 46.00

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Purity: 99.48%

Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Acotiamide hydrochloride, YM-443 HCl, Z-338 HCl
Molecular Weight	541.06
Formula	C21H37ClN4O8S
CAS No.	773092-05-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 27.5 mg/mL (50.83 mM)

References and Literature

1. Kawachi M,et al. Eur J Pharmacol. 2011 Sep;666(1-3):218-25.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Drug Repurposing Compound Library Anti-Neurodegenerative Disease Compound Library Bioactive Compounds Library Max Approved Drug Library NO PAINS Compound Library Neurotransmitter Receptor Compound Library Anti-Infection Compound Library Neuronal Signaling Compound Library Anti-Alzheimer's Disease Compound Library

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Keywords

Acotiamide monohydrochloride trihydrate 773092-05-0 Neuroscience AChE functional dyspepsia intestinal inflammatory Acotiamide hydrochloride NR8383 Acotiamide monohydrochloride inhibit macrophage gastric emptying Cholinesterase (ChE) YM-443 HCl Inhibitor Acotiamide Acotiamide monohydrochloride Trihydrate Acotiamide Hydrochloride gastric motility Z-338 HCl inhibitor

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