polyp — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T21294	Polmacoxib	CG-100649,CG100649,CG 100649	COX , Carbonic Anhydrase
	Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through...		COX , Carbonic Anhydrase
TP1044L	Pancreatic Polypeptide, rat acetate		Neuropeptide Y Receptor
	Pancreatic Polypeptide, rat acetate is an agonist of NPY receptor, with high affinity at NPYR4.		Neuropeptide Y Receptor
S00015	Tea polyphenol		Apoptosis , Others , Autophagy
	Tea polyphenol, also called green tea extract, are a mixture of chemical compounds, such as flavanoids and tannins, found naturally in tea. Polyphenols are powerful antioxidants, which can reduce the risk of developing c...		Apoptosis , Others , Autophagy
T3895	Polyphyllin I		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
	Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha...		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
T3894	Polyphyllin II	Chonglou Saponin II	Apoptosis , Others
	Polyphyllin II (Chonglou Saponin II) has hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy kill sperm effects.		Apoptosis , Others
T6S2315	Polyphyllin VI		Apoptosis , Antibacterial , Pyroptosis
	1. Polyphyllin VI has hemostasis , expectorant , bacteriostasis, anticytotoxic, anti pregnancy kill sperm effects.		Apoptosis , Antibacterial , Pyroptosis
TN6908	Polyporusterone A	(1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R,5S)-2,3-dihydroxy-5,6-dimethylheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one
	Polyporusterone A is a triterpene carboxylic acid derived from the substrates of P. umbellatus.Polyporusterone A inhibits free radical-induced erythrocyte cleavage (hemolysis), and can be used in studies of hair regenera...
TP1137L	Pancreatic Polypeptide (human) acetate		Neuropeptide Y Receptor
	Pancreatic Polypeptide (human) acetate is a C-terminally amidated 36 amino acid peptide, which acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist.		Neuropeptide Y Receptor
TN1010	Polyphyllin H		Others
	Polyphyllin H can be extracted from loblolly pine and rhizomes, has antitumor activity, and is used in studies of inflammation, fractures, and convulsions.		Others
TN6909	Polyporusterone B	(1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one	Others
	Polyporusterone B ((1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one) is a triterpene carboxylic aci...		Others
TN1153	Polyporenic acid C		Apoptosis , PARP , Caspase , PI3K
	Polyporenic acid C shows inhibitory activity against human collagenase.		Apoptosis , PARP , Caspase , PI3K
TP1137	Pancreatic Polypeptide, human	Human pancreatic polypeptide
	Endogenous high affinity agonist for human NPY Y4 receptor (Ki = 0.056 nM). Believed to play an important role in the function of the gastrointestinal tract.
T76538	Pancreatic polypeptide
	Pancreatic polypeptide, a peptide produced by the pancreas's endocrine PP cells, modulates pancreatic secretory functions and influences hepatic glycogen levels and gastrointestinal secretion [1].
TP1044	Pancreatic Polypeptide, rat	Rat pancreatic polypeptide
	Pancreatic Polypeptide, rat is an agonist of NPY receptor, with high affinity at NPYR4. Pancreatic polypeptide (PP) is a 36-amino acid, C-terminally amidated peptide, and is a member of the PP-fold peptide family. It is ...
TN2094	Polyphyllin E		Others
	Polyphyllin E has synergistic anticancer effects.		Others
TN2093	Polyphyllin C		Others
	Polyphyllin C is a natural product		Others
T81425	Polyporusterone C
	Polyporusterone C (Compound 3), a natural product extracted from Polyporus umbellatus, exhibits cytotoxic activities, displaying IC50 values of 37, 26, and 42 μg/mL against L-1210 cells after 3, 5, and 7 days of treatmen...
T81428	Polypectate sodium	pectate sodium
	Polypectate sodium, a principal constituent of cell wall polysaccharides (pectins), serves as a carbon source and triggers polygalacturonase production. It is also employed to assess alkaline-active and stable pectate ly...
T82332	Gastric Inhibitory Polypeptide (6-30) amide (human)
	Gastric Inhibitory Polypeptide (6-30) amide (human) is an incretin hormone utilized in the research of diabetes [1].
T75913	[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic polypeptide TFA
	[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent, selective neuropeptide Y Y5 receptor agonist, demonstrating binding affinity with an IC50 of 0.24 nM for the hY5 receptor. This compound significan...