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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0070 | Pentoxifylline | Oxpentifylline,PTX,BL-191 | HIV Protease , PDE , Adenosine Receptor , Autophagy |
Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet ... | |||
T0543 | 7-Methylxanthine | Heteroxanthine,Heteroxanthin | Nucleoside Antimetabolite/Analog , Endogenous Metabolite |
7-Methylxanthine (Heteroxanthine), a methyl derivative of xanthine, is one of the purine components in urinary calculi. 7-Methylxanthine appears to prevent FDM in pigmented rabbits by remodeling the posterior sclera. | |||
T2P2806 | Hederacolchiside A1 | Raddeanoside R13 | Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR |
Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacol... | |||
T20150 | C.I. 37505 | 3-Hydroxy-2-naphthanilide,2-Naphthanilide, 3-hydroxy- (8CI) | |
C.I. 37505 is an azo dye coupling component.It implicated in occupational pigmented contact dermatitis. | |||
TN4179 | Haginin A | ERK , Tyrosinase , Akt | |
Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB activation, MITF, and also by the subsequent downregulation of t... | |||
T76868 | Lacnotuzumab | ||
Lacnotuzumab (MCS110), a humanized IgG1/κ monoclonal antibody, neutralizes and inhibits the interaction between CSF-1 and its receptor, CSF-1R. It is utilized in researching pigmented villonodular synovitis [1] [2]. | |||
T62730 | TDRL-X80 | ||
TDRL-X80 is a potent inhibitor of the pigmented dry skin protein (XPA). TDRL-X80 inhibits the DNA binding activity of XPA. TDRL-X80 acts on single, double and cisplatin damaged DNA with IC50 values of 18, 20 and 29 μM in... | |||
T38048 | Globotetraosylceramides (porcine RBC) | ||
Globotetraosylceramides are bioactive neutral glycosphingolipids. They are the major glycolipids in human erythrocytes. They act as receptors for the Shiga toxins Stx1, Stx2, and Stx2e, the cytotoxic protein pierisin-1, ... |