ocular — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6424	Bromfenac Sodium	AHR 10282B,Bronuck,AHR 10282R	COX
	Bromfenac Sodium (AHR 10282R) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.		COX
T12670	(Rac)-MGV354	MGV354	Others
	(Rac)-MGV354 (MGV354) is the racemate of MGV354. MGV354 is a soluble activator of guanylate cyclase (sGC)(EC50s of <0.5 nM, and 5 nM in CHO and GTM-3 E cells, respectively).		Others
T2403	Bromfenac sodium hydrate	Bromfenac sodium,Bromfenac monosodium salt sesquihydrate	COX
	Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is the sodium salt form of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory activities. Upon ophthalmic admi...		COX
T26923	Bunazosin Hydrochloride	E 1015,E643,E-1015,E-643,E 643	Adrenergic Receptor
	Bunazosin Hydrochloride (E 1015) is an alpha(1)-adrenoceptor antagonist used as a systemic antihypertensive and an ocular hypotensive drug.		Adrenergic Receptor
T6422	Brimonidine Tartrate	AGN190342 tartrate,304 tartrate,AGN190342 (tartrate),UK 14304 (tartrate),UK14304 tartrate	Adrenergic Receptor
	Brimonidine Tartrate (AGN190342 tartrate) is a quinoxaline derivative and adrenergic α-2 receptor agonist (EC50: 0.45 nM) that is used to manage intraocular pressure associated with open-angle glaucoma or ocular hyperten...		Adrenergic Receptor
T2538	Bimatoprost	AGN 192024	Prostaglandin Receptor
	Bimatoprost (AGN 192024) is a cloprostenol-derived amide that is used as an antihypertensive agent in the treatment of open-angle glaucoma and ocular hypertension.		Prostaglandin Receptor
T6472	Difluprednate	Myser,Epitopic,CM 9155	Others
	Difluprednate (Myser)(Durezol) is a corticosteroid, approved for the treatment of post-operative ocular inflammation and pain.		Others
T68120L	Ot-730 HCl	Ot-730 HCl(870809-51-1 Free base)	Others
	ot-730 HCl is a novel selective beta blocker prodrug for the study of ocular diseases.		Others
T20157	Brimonidine	AGN190342,Bromoxidine,AGN 190342,AGN-190342	Adrenergic Receptor
	Brimonidine (Bromoxidine) is a drug used as eye drops under the brand names Alphagan and Alphagan-P. It is used to treat open-angle glaucoma or ocular hypertension		Adrenergic Receptor
T2528	Latanoprost	Xalatan,PHXA41	GPR , Prostaglandin Receptor , RAR/RXR
	Latanoprost (Xalatan) is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect.		GPR , Prostaglandin Receptor , RAR/RXR
T3174	Taprenepag	CP-544326	Prostaglandin Receptor
	Taprenepag (CP-544326) (CP-544326) is a potent and selective prostaglandin E2 receptor agonist (EC50 = 2.8 nM). Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle.		Prostaglandin Receptor
T5841	Travoprost	Flu-Ipr,Fluprostenol isopropyl ester,AL6221	Prostaglandin Receptor
	Travoprost (Fluprostenol isopropyl ester) is used to treat glaucoma and ocular hypertension,is a potent and selective FP prostaglandin receptor agonist.		Prostaglandin Receptor
T7423	Diquafosol tetrasodium	INS365	P2Y Receptor
	Diquafosol Tetrasodium is a P2Y2 receptor agonist that stimulates the secretion of mucins from ocular tissues Diquafosol tetrasodium (INS365) improves tear film stability and visual function, as a topical treatment of dr...		P2Y Receptor
T0397	Tetrahydrozoline	Tetryzolin,Tetryzoline	Adrenergic Receptor
	Tetrahydrozoline (Tetryzoline), an alpha agonist, have an effect on the constriction of conjunctival blood vessels. This contributes to relieve the redness of the eye resulted from minor ocular irritants.		Adrenergic Receptor
T15719	Latanoprostene bunod	LBN,NCX116	Others
	Latanoprostene bunod (LBN) is nitric oxide (NO)-donating prostaglandin F2a analog and is a topical ophthalmic therapeutic. It is used for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma o...		Others
T73400L	PG-11047 2HCl	PG-11047 2HCl(949933-50-0 Free base),CGC-11047 2HCl	Apoptosis
	PG-11047 2HCl is an apoptosis-stimulating agent used in the treatment of genitourinary disorders, immune system disorders, genetic disorders and malformations, ocular disorders, and disorders of the blood and lymphatic s...		Apoptosis
T77600	Methyl-4-oxoretinoate		Apoptosis
	Methyl-4-oxoretinoate is a synthetic retinoid compound with anticancer compounds that can induce differentiation and apoptosis in cancer cells.Methyl-4-oxoretinoate is used in the treatment of acne, psoriasis, and other ...		Apoptosis
T1281	Tropicamide	Ro 1-7683	AChR
	Tropicamide (Ro 1-7683) is a synthetic muscarinic antagonist with actions similar to atropine and with an anticholinergic property. Upon ocular administration, tropicamide binds to and blocks the muscarinic receptors in ...		AChR
T3979	Emedastine	LY188695,Emadine	Histamine Receptor
	Emedastine (LY188695) is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity. Emedastine reversibly and competitively blocks histamine by binding to H1 receptors, thus blocking its...		Histamine Receptor
T32458	L 653328	L 653,328,L653328,L653,328,L-653,328,L-653328
	L 653328 is an ocular hypotensive agent that has modest beta-receptor blocking activity.