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Brimonidine

Catalog No. T20157 CAS 59803-98-4

Synonyms: AGN190342, Bromoxidine, AGN 190342, AGN-190342

Brimonidine (Bromoxidine) is a drug used as eye drops under the brand names Alphagan and Alphagan-P. It is used to treat open-angle glaucoma or ocular hypertension

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Brimonidine, CAS 59803-98-4

Pack Size	Availability	Price/USD
5 mg	In stock	$ 52.00
10 mg	In stock	$ 89.00
25 mg	In stock	$ 183.00
50 mg	In stock	$ 356.00
100 mg	In stock	$ 529.00
500 mg	In stock	$ 1,180.00
1 mL * 10 mM (in DMSO)	In stock	$ 58.00

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Purity: 98.60%

Biological Description

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Storage & Solubility Information

Description	Brimonidine (Bromoxidine) is a drug used as eye drops under the brand names Alphagan and Alphagan-P. It is used to treat open-angle glaucoma or ocular hypertension
In vitro	[3H]Brimonidine is a full agonist at alpha 2-adrenergic receptors labeling at least 2 specific binding sites in the human brain that both have the characteristics of an alpha 2-adrenergic binding site. GTP decreases agonist binding at both of these sites, but with different potencies at each site [1].

Synonyms	AGN190342, Bromoxidine, AGN 190342, AGN-190342
Molecular Weight	292.13
Formula	C11H10BrN5
CAS No.	59803-98-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 26 mg/mL (89.0 mM)

References and Literature

1. Chopin, P., F.C. Colpaert, and M. Marien, Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway. J Pharmacol Exp Ther, 1999. 288(2): p. 798-804. 2. Andorn, A.C., M.A. Carlson, and R.C. Gilkeson, Specific [3H]UK 14,304 binding in human cortex occurs at multiple high affinity states with alpha 2-adrenergic selectivity and differing affinities for GTP. Life Sci, 1988. 43(22): p. 1805-12.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Neurodegenerative Disease Compound Library GPCR Compound Library Drug Repurposing Compound Library Anti-Cancer Clinical Compound Library Anti-Cancer Approved Drug Library EMA Approved Drug Library Anti-Cancer Drug Library Anti-Cancer Compound Library Bioactive Compounds Library Max ReFRAME Related Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Brimonidine 59803-98-4 GPCR/G Protein Neuroscience Adrenergic Receptor Beta Receptor AGN190342 UK14304 inhibit Bromoxidine UK 14304 AGN 190342 Inhibitor AGN-190342 UK-14304 inhibitor

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