mutagenic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T13457	(Z)-9-Propenyladenine	(Z)-Mutagenic Impurity of Tenofovir Disoproxil	Others
	(Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate.		Others
T12127	9-Propenyladenine	Mutagenic Impurity of Tenofovir Disoproxil,Tenofovir Impurity 2	Others
	9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate.		Others
T19412	Macrozamin		Others
	Macrozamin has carcinogenic, mutagenic, teratogenic and neurotoxic properties.Macrozamin is a natural product isolated from Cycads.		Others
T5363	Tempo	2,2,6,6-Tetramethylpiperidinooxy	Free radical scavengers , Reactive Oxygen Species , DNA/RNA Synthesis , Mitochondrial Metabolism
	Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a structural probe in electron spin resonance spectroscopy.
T2895	Lupeol	Fagarasterol,Monogynol B,Clerodol,(3β,13ξ)-Lup-20(29)-en-3-ol,Farganasterol	Apoptosis , Androgen Receptor , Akt
	Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity.		Apoptosis , Androgen Receptor , Akt
T20760	Benzidine orange	DCC-1802,Polymo Orange GR,Oralith Orange PG,DCC 1802,DCC1802	Others
	Benzidine orange (DCC-1802) shows mutagenic and carcinogenic activity.		Others
T2863	P-Coumaric acid	para-Coumaric Acid,4-Hydroxycinnamic acid,trans-4-Hydroxycinnamic acid,Trans-p-Coumaric acid,4-Coumaric acid,P-Hydroxycinnamic acid	Endogenous Metabolite , Antibiotic
	p-Coumaric acid (para-Coumaric Acid) is the abundant isomer of cinnamic acid, with antitumor and anti-mutagenic activities.		Endogenous Metabolite , Antibiotic
T15611	JH-RE-06		DNA/RNA Synthesis
	JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), which targets REV1 that interact...		DNA/RNA Synthesis
TN1683	Gentisin		DNA/RNA Synthesis
	Gentisin is a novel inhibitor of vascular smooth muscle cells (VSMC) proliferation with an IC50 value of 7.84 μM. Gentisin has mutagenic activity.		DNA/RNA Synthesis
TJS0405	Lucidin	NSC 30546,Henine	Others
	1. Lucidin (NSC-30546) and its derivatives are genotoxic, it is mutagenic at the hypoxanthine-guanine phosphoribosyl transferase gene locus.		Others
T68110	Moxnidazole
	Moxnidazole, a 5-nitroimidazole, is mutagenic in microbial assays and in Drosophila, inducing genetic alterations in mouse somatic cells.
T9049	Difurazon hydrochloride		Others
	Difurazon hydrochloride is a mutagenic drug . Difurazon hydrochloride may has been used to treat bacillary dysentery. It is an antibacterial growth promoter in animal feeds.		Others
T4169	N-Nitroso-N-methylurea	1-Methyl-1-nitrosourea,N-Methyl-N-nitrosourea,Methylnitrosourea	Others , DNA Alkylator/Crosslinker
	N-Nitroso-N-methylurea (Methylnitrosourea) is a nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.		Others , DNA Alkylator/Crosslinker
T2801	Aristolochic acid A	TR 1736,Aristolochin,Aristolochine,Aristolochic Acid I,Aristolochic Acid	Others , NF-κB
	Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort (Aristolochiaceae) family of plants.		Others , NF-κB
T5746	Dictamine	Dictamnine,Dectamine	Apoptosis , Anti-infection , Antibacterial , Antifungal
	Dictamine (Dectamine) shows anticholinesterase, anti-inflammatory, mutagenic, and has antimicrobial activity against bacteria and fungi. It has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma...		Apoptosis , Anti-infection , Antibacterial , Antifungal
T19859	Nicosulfuron	Milagro,Accent,Motivell	Others
	Nicosulfuron (Milagro) is a pesticide that works by inhibiting the acetolactate synthase enzyme. Nicosulfuron has not been found to induce mutagenic or carcinogenic effects. Nicosulfuron is a herbicide to protect corn cr...		Others
T4832	Cytosine	6-Aminopyrimidin-2(1H)-one,4-Amino-2-hydroxypyrimidine,Cytosinimine	Endogenous Metabolite
	Cytosine (6-Aminopyrimidin-2(1H)-one) is a pyrimidine base that is a fundamental unit of nucleic acids. The deamination of cytosine alone is apparent and the nucleotide of cytosine is the prime mutagenic nucleotide in le...		Endogenous Metabolite
TN1078	Seneciphylline		P450 , GST
	Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, has mutagenic activity in Drosophila and their transfer into rat milk.Seneciphylline can significantly increased the activities of epoxide hydrase and glutat...		P450 , GST
T19165	8-Hydroxyguanine	8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine	Endogenous Metabolite
	8-Hydroxyguanine (8 Hydroxyguanine) is the major premutagenic damage produced by reactive oxygen species. It causes G-T and A-C substitutions.8-Hydroxyguanine is a biomarker for RNA oxidation and oxidative DNA damage.8-H...		Endogenous Metabolite
T19317	Ethyl phenylacetate		Others
	Ethyl phenylacetate is a “greener" solvent with low toxicity. Ethyl phenylacetate is a non-mutagenic and is a Kosher food additive. Ethyl phenylacetate gives the wines a strong honey-like character. Ethyl phenylacetate i...		Others