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Cytosine

Name: Cytosine
Brand: TargetMol
SKU: T4832
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T4832Cas No. 71-30-7

Alias Cytosinimine, 6-Aminopyrimidin-2(1H)-one, 4-Amino-2-hydroxypyrimidine

Cytosine (6-Aminopyrimidin-2(1H)-one) is a pyrimidine base that is a fundamental unit of nucleic acids. The deamination of cytosine alone is apparent and the nucleotide of cytosine is the prime mutagenic nucleotide in leukaemia and cancer.

Cytosine

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Purity: 99.67%

Catalog No. T4832Alias Cytosinimine, 6-Aminopyrimidin-2(1H)-one, 4-Amino-2-hydroxypyrimidineCas No. 71-30-7

Pack Size	Price	Availability	Quantity
500 mg	$41	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock

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Batch Information

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Purity:99.67%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Cytosine (6-Aminopyrimidin-2(1H)-one) is a pyrimidine base that is a fundamental unit of nucleic acids. The deamination of cytosine alone is apparent and the nucleotide of cytosine is the prime mutagenic nucleotide in leukaemia and cancer.
Synonyms	Cytosinimine, 6-Aminopyrimidin-2(1H)-one, 4-Amino-2-hydroxypyrimidine

Chemical Properties

Molecular Weight	111.1
Formula	C₄H₅N₃O
Cas No.	71-30-7
Smiles	NC1=NC(=O)NC=C1
Relative Density.	0.48

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (270.03 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (9 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	9.0009 mL	45.0045 mL	90.0090 mL	450.0450 mL
5 mM	1.8002 mL	9.0009 mL	18.0018 mL	90.0090 mL
10 mM	0.9001 mL	4.5005 mL	9.0009 mL	45.0045 mL
20 mM	0.4500 mL	2.2502 mL	4.5005 mL	22.5023 mL
50 mM	0.1800 mL	0.9001 mL	1.8002 mL	9.0009 mL
100 mM	0.0900 mL	0.4500 mL	0.9001 mL	4.5005 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc